Search results for "48"
showing 10 items of 1388 documents
Integral functions of marine vertebrates in the ocean carbon cycle and climate change mitigation
2021
Summary In the last decade, the ocean has absorbed a quarter of the Earth’s greenhouse gas emissions through the carbon (C) cycle, a naturally occurring process. Aspects of the ocean C cycle are now being incorporated into climate change mitigation and adaptation plans. Currently, too little is known about marine vertebrate C functions for their inclusion in policies. Fortunately, marine vertebrate biology, behavior, and ecology through the lens of C and nutrient cycling and flux is an emerging area of research that is rich in existing data. This review uses literature and trusted data sources to describe marine vertebrate C interactions, provides quantification where possible, and highligh…
Ethical Leaders Promote Quality of Life Through Fair and Trust-based Relationships
2020
Ethical leadership has become an important field of research. This article examines the impact of ethical leadership within the context of healthcare organizations. Based on social learning theory, we examine the relationship between ethical leadership and quality of life, mediated by peer justice and moderated by trust in the leader. Participants in this study consisted of 388 professionals from 59 centers affiliated with “Plena Inclusión”, an NGO whose mission is to improve the quality of life of individuals with intellectual disabilities in Spain. Results showed a significant relationship between ethical leadership and quality of life, through a partial mediation of overall peer justice.…
Cancer Stem Cells and Neuroblastoma: Characteristics and Therapeutic Targeting Options
2019
The majority of embryonal tumors or childhood blastomas derive from pluripotent progenitors or fetal stem cells that acquire cancer stem cell (CSC) properties: multipotency, self-renewal ability, metastatic potential, chemoresistance, more pronounced levels of drug transporters, enhanced DNA-damage repair mechanisms, and a quiescent state. Neuroblastoma (NB) is considered a neuroendocrine tumor and is the most common extracranial neoplasm in children. NB pathogenesis has frequently been associated with epigenetic dysregulation and a failure to implement a differentiation program. The origin, characteristics, and isolation of the CSC subpopulation in NB are still incompletely understood, des…
Estrogens and Stem Cells in Thyroid Cancer
2014
Recent discoveries highlight the emerging role of estrogens in the initiation and progression of different malignancies through their interaction with stem cell compartment. Estrogens play a relevant role especially for those tumors bearing a gender disparity in incidence and aggressiveness, as occurs for most thyroid diseases. Although several experimental lines suggest that estrogens promote thyroid cell proliferation and invasion, their precise contribution in stem cell compartment still remains unclear. This review underlines the interplay between hormones and thyroid function, which could help to complete the puzzle of gender discrepancy in thyroid malignancies. Defining the associatio…
Current and/ or life time use of cannabis as a factor of vulnerability in psychotic disorders
2014
Metabolic disorders during pregnancy and postpartum cardiometabolic risk
2018
Hormonal changes during pregnancy can trigger gestational diabetes (GDM), which is constantly increasing. Its main characteristic is pronounced insulin resistance, but it appears to be a multifactorial process involving several metabolic factors; taken together, the latter leads to silent or clinically evident cardiovascular (CV) events. Insulin resistance and central adiposity are of crucial importance in the development of metabolic syndrome, and they appear to correlate with CV risk factors, including hypertension and atherogenic dyslipidaemia. Hypertensive disease of pregnancy (HDP) is more likely to be an accompanying co-morbidity in pregnancies complicated with GDM. There is still inc…
REAL HUMANS? : Affective imaginaries of the human and its Others in the Swedish TV series Äkta människor
2019
According to the Swedish science fiction TV series Äkta människor (Real Humans, SVT and Matador film 2012-2014), humanoid robots called “hubots” are replacing the human workforce in care work and assembly line industries. Against the backdrop of current debates about immigration and citizenship in the Nordic countries, this article does a close, contextual reading of the series, exploring how the hubots influence work and family life. We are particularly interested in how hubots tie in with the cultural circulation of affect in relation to Otherness and how responses towards the “not-quite” human or dehumanized Other are negotiated in the present-day Nordic cultural imaginaries. What kinds …
Les études hédoniques soutiennent-elles une valeur verte élevée dans le bâtiment ? Une réponse par la méta-analyse
2018
International audience; La place majeure occupée par le secteur du bâtiment dans la consommation d'énergie (40%) et les émissions de gaz à effet de serre (1/3 des émissions) explique le développement du débat scientifique axé sur la réduction de l'impact environnemental du bâtit et sur ses leviers. Ces dernières années ont notamment vu croitre une littérature considérable relative à la disposition à payer du public pour les bâtiments « verts » labélisés par des écolabels, cette « valeur verte » étant estimée dans la grande majorité des études via des modèles hédoniques. Dans cet article, nous proposons d'offrir une synthèse de ces résultats dans le cadre d'une méta-analyse portant sur plus …
Persistent photovoltage in methylammonium lead iodide perovskite solar cells
2014
Open circuit voltage decay measurements are performed on methylammonium lead iodide (CH3NH3PbI3) perovskite solar cells to investigate the charge carrier recombination dynamics. The measurements are compared to the two reference polymer-fullerene bulk heterojunction solar cells based on P3HT:PC60BM and PTB7:PC70BM blends. In the perovskite devices, two very different time domains of the voltage decay are found, with a first drop on a short time scale that is similar to the organic solar cells. However, two major differences are also observed. 65-70% of the maximum photovoltage persists on much longer timescales, and the recombination dynamics are dependent on the illumination intensity.
Organic derivatives of mercury and tin as promoters of membrane lipid peroxidation.
2008
The toxicity mechanisms of mercury and tin organic derivatives are still under debate. Generally the presence of organic moieties in their molecules makes these compounds lipophilic and membrane active species. The recent results suggest that Hg and Sn compounds deplete HS-groups in proteins, glutathione and glutathione-dependent enzymatic systems; this process also results in the production of reactive oxygen species (ROS), the enhancement of membrane lipids peroxidation and damage of the antioxidative defence system. The goal of this review is to present recent results in the studies oriented towards the role of organomercury and organotin compounds in the xenobiotic-mediated enhancement …