Search results for "54"

showing 10 items of 2200 documents

Early and midterm outcomes of bioresorbable vascular scaffolds for ostial coronary lesions: insights from the GHOST-EU registry.

2016

Aims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subset, with higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long term, but their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA), left anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular death, target vessel m…

LCX (29Target lesionMale52%). Patients presenting with ostial lesions did not differ from the remaining cohort except for a higher incidence of prior revascularisation. Predilation was performed in 97% of the lesions (vs. 96% in non-ostialp= 0.035)medicine.medical_treatmentMyocardial Infarction304 patients with a mean age of 62 +/- 11years. There were 90 ostial lesions (5.8%) in 84 patients (6.4%) located at the ostial RCA (14Coronary Artery Disease030204 cardiovascular system & hematologyCoronary artery diseasebut their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA)0302 clinical medicineAbsorbable Implants030212 general & internal medicineMyocardial infarctionCircumflexRegistriesTissue Scaffolds32%)Drug-Eluting StentsMiddle AgedThrombosisCoronary VesselsAims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subset with higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long term but their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA) left anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular death target vessel myocardial infarction or target lesion revascularisation. The database included a total of 1549 lesions in 1304 patients with a mean age of 62 +/- 11years. There were 90 ostial lesions (5.8%) in 84 patients (6.4%) located at the ostial RCA (14; 16%) LCX (29; 32%) or LAD (47; 52%). Patients presenting with ostial lesions did not differ from the remaining cohort except for a higher incidence of prior revascularisation. Predilation was performed in 97% of the lesions (vs. 96% in non-ostial p= 0.618) post-dilation in 43% (versus 58% in the non-ostial group p= 0.008). At quantitative coronary angiography treatment of ostial lesions was associated with higher residual stenosis (30% [23-41] vs. 26% [20-37] p= 0.035) but no difference in minimum lumen diameter existed (p= 0.447). Follow-up data were available at 385 [362-465] days. The 12-month Kaplan-Meier estimated rates of scaffold thrombosis were 4.9% and 2.0% (ostial and non-ostial lesion groups respectively log-rank p= 0.005). The device-oriented composite endpoint occurred respectively in 12.6% and 4.6% at 12 months (log-rank p= 0.001). Treatment of ostial lesions was an independent predictor of this endpoint (p= 0.0025 HR 2.65 [1.41-4.97]).OstiumAims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subsetTreatment Outcomein 12.6% and 4.6% at 12 months (log-rank p= 0.001). Treatment of ostial lesions was an independent predictor of this endpoint (p= 0.0025CardiologyFemale549 lesions in 1medicine.symptomCardiology and Cardiovascular MedicineAdultpost-dilation in 43% (versus 58% in the non-ostial groupmedicine.medical_specialtyor LAD (47HR 2.65 [1.41-4.97])but no difference in minimum lumen diameter existed (p= 0.447). Follow-up data were available at 385 [362-465] days. The 12-month Kaplan-Meier estimated rates of scaffold thrombosis were 4.9% and 2.0% (ostial and non-ostial lesion groupsrespectivelyLesion03 medical and health sciencesPercutaneous Coronary Interventionwith higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long termleft anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular deathInternal medicinemedicineHumanstarget vessel myocardial infarction or target lesion revascularisation. The database included a total of 1Agedp= 0.008). At quantitative coronary angiographybusiness.industryPercutaneous coronary interventionp= 0.618)treatment of ostial lesions was associated with higher residual stenosis (30% [23-41] vs. 26% [20-37]log-rank p= 0.005). The device-oriented composite endpoint occurredmedicine.diseaseSurgery16%)businessEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
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Baktērijas Borrelia burgdorferi virsmas lipoproteīna BBA03 strukturālie pētījumi

2019

Laima slimība ir visizplatītākā ar vektoriem pārnēsātā slimība Ziemeļu puslodē. Neraugoties uz tās izplatību un smagajiem slimības simptomiem, vēl aizvien nav līdz galam izprasts tās izraisītājas (Borrelia burgdorferi) infekcijas mehānisms. Darba mērķis bija producēt B. burgdorferi ar membrānu saistīto lipoproteīnu BBA03 un noteikt tā telpisko struktūru, izmantojot kodolu magnētisko rezonansi. BBA03 sastāv no 38 aminoskābes garas nestrukturētas ķēdes proteīna N-galā, kam seko septiņas α-spirāles. Izmantojot Dali serveri tika konstatēts, ka BBA03 tuvākais strukturālais analogs ir mlp proteīnu saimes pārstāvis - BBP28. Neraugoties uz to homoloģiju, iepriekšējie pētījumi norāda uz abu proteīnu…

Laima slimībaBBA03Borrelia burgdorferilp54Bioloģijakodolu magnētiskā rezonanse
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Designing biochar properties through the blending of biomass feedstock with metals: Impact on oxyanions adsorption behavior

2018

Metal-blending of biomass prior to pyrolysis is investigated in this work as a tool to modify biochar physico-chemical properties and its behavior as adsorbent. Six different compounds were used for metal-blending: AlCl3, Cu(OH)2, FeSO4, KCl, MgCl2 and Mg(OH)2. Pyrolysis experiments were performed at 400 and 700 °C and the characterization of biochar properties included: elemental composition, thermal stability, surface area and pore size distribution, Zeta potential, redox potential, chemical structure (with nuclear magnetic resonance) and adsorption behavior of arsenate, phosphate and nitrate. Metalblending strongly affected biochars' surface charge and redox potential. Moreover, it incre…

LangmuirEnvironmental EngineeringP06 - Sources d'énergie renouvelableHealth Toxicology and Mutagenesishttp://aims.fao.org/aos/agrovoc/c_290360208 environmental biotechnology02 engineering and technology010501 environmental sciences01 natural sciencesRedoxchemistry.chemical_compoundAdsorptionBiocharPhysico-chemicalBiomasseZeta potentialEnvironmental ChemistrySurface chargeBiomassOxydation0105 earth and related environmental scienceshttp://aims.fao.org/aos/agrovoc/c_26874Designer biocharMetalPublic Health Environmental and Occupational HealthArsenateGeneral MedicineGeneral ChemistryOxyanionPore size distributionMétalPollutionMetal-blendingU50 - Sciences physiques et chimie020801 environmental engineeringhttp://aims.fao.org/aos/agrovoc/c_926chemistryChemical engineeringMetalsCharcoalCharbonPyrolyseAdsorptionhttp://aims.fao.org/aos/agrovoc/c_5472Pyrolysishttp://aims.fao.org/aos/agrovoc/c_1693
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Dominique Hölzle. Le roman libertin au XVIIIe siècle: une esthétique de la séduction, Oxford, Voltaire Foundation, 2012, 285 pagine.

2018

Language. Linguistic theory. Comparative grammarP101-410PC1-5498Romanic languagese-Scripta Romanica
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Mobility of the Singly-Charged Lanthanide and Actinide Cations: Trends and Perspectives

2020

The current status of gaseous transport studies of the singly-charged lanthanide and actinide ions is reviewed in light of potential applications to superheavy ions. The measurements and calculations for the mobility of lanthanide ions in He and Ar agree well, and they are remarkably sensitive to the electronic configuration of the ion, namely, whether the outer electronic shells are 6s, 5d6s or 6s$^2$. The previous theoretical work is extended here to ions of the actinide family with zero electron orbital momentum: Ac$^+$ (7s$^2$, $^1$S), Am$^+$ (5f$^7$7s $^9$S$^\circ$), Cm$^+$ (5f$^7$7s$^2$ $^8$S$^\circ$), No$^+$ (5f$^{14}$7s $^2$S) and Lr$^+$ (5f$^{14}$7s$^2$ $^1$S). The calculations rev…

LanthanideAtomic Physics (physics.atom-ph)Ab initioFOS: Physical sciences02 engineering and technologyElectroninteraction potential010402 general chemistry7. Clean energy01 natural sciencesPhysics - Atomic PhysicsIonlcsh:Chemistryion mobilityAtomlanthanideselectronic configurationOriginal ResearchPhysicsIonic radiussuperheavy ionsactinidesGeneral ChemistryActinide021001 nanoscience & nanotechnology3. Good health0104 chemical sciencesChemistrylcsh:QD1-999ddc:540Electron configurationAtomic physics0210 nano-technology
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The Role of Palliative Radiotherapy in the Treatment of Spinal Bone Metastases from Head and Neck Tumors-A Multicenter Analysis of a Rare Event.

2020

This retrospective multi-center analysis aimed to assess the clinical response and stabilizing effects of palliative radiotherapy (RT) for spinal bone metastases (SBM) in head and neck cancer (HNC), and to establish potential predictive factors for stability and overall survival (OS). Patients included in this analysis were treated at the University Hospitals of Mainz, Freiburg, and Heidelberg between 2001 and 2019. Clinical information was taken from the medical records. The stability of affected vertebral bodies was assessed according to the validated spine instability neoplastic score (SINS) based on CT-imaging before RT, as well as 3 and 6 months after RT. OS was quantified as the time …

LarynxCancer Researchmedicine.medical_specialtymedicine.medical_treatmentlcsh:RC254-282GastroenterologyArticleMetastasis03 medical and health sciences0302 clinical medicineInternal medicineMedicineSINSradiotherapyPerformance statusbusiness.industryProportional hazards modelPharynxHead and neck cancerBone metastasisspinal bone metastaseslcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaseRadiation therapyinstabilitymedicine.anatomical_structureOncology030220 oncology & carcinogenesishead and neck cancerbusiness030217 neurology & neurosurgeryCancers
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Acute tissue damage induced by monopolar microelectrodes and radiofrequency in vocal cords after transoral cordectomy

2021

Abstract Introduction: In 2006 and 2009, we reported the levels of acute and chronic tissue damage after cordectomy associated with use of the microlectrodes using high frequency energy. In 2010, we shifted to radiofrequency rather than high frequency electrogenerators. Objective: The aim of this study is to evaluate acute tissue damage in the larynx after cordectomy using microelectrodes coupled to a radiofrequencygenerator. Methods: We studied 22 patients with a stage T1 glottic squamous cell carcinoma. The patients were randomly assigned to the two operating mode: cutting or coagulation (11 patients each mode). The strength of the study is that there are no previous studies on the effect…

LarynxGlottismedicine.medical_specialtyCordVocal Cords03 medical and health sciences0302 clinical medicineMicroeletrodosTissue damagemedicineHumansLaryngeal surgery030223 otorhinolaryngologyLaryngeal Neoplasmsbusiness.industryDano tecidualTissue damageRadiofrequênciaCorda vocalGlottic Squamous Cell CarcinomaMicroelectrodemedicine.anatomical_structureOtorhinolaryngologyRF1-547Vocal cord030220 oncology & carcinogenesisHemostasisRadiofrequencyCordectomyLaser TherapyRadiologybusinessMicroelectrodes
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Leptin/HER2 crosstalk in breast cancer: in vitro study and preliminary in vivo analysis.

2008

Abstract Background Obesity in postmenopausal women is associated with increased breast cancer risk, development of more aggressive tumors and resistance to certain anti-breast cancer treatments. Some of these effects might be mediated by obesity hormone leptin, acting independently or modulating other signaling pathways. Here we focused on the link between leptin and HER2. We tested if HER2 and the leptin receptor (ObR) can be coexpressed in breast cancer cell models, whether these two receptors can physically interact, and whether leptin can transactivate HER2. Next, we studied if leptin/ObR can coexist with HER2 in breast cancer tissues, and if presence of these two systems correlates wi…

LeptinTranscriptional Activationmedicine.medical_specialtyCancer ResearchReceptor ErbB-2Breast Neoplasmslcsh:RC254-282Breast cancerSurgical oncologyRisk FactorsInternal medicineCell Line TumormedicineGeneticsHumansObesityReceptorskin and connective tissue diseasesneoplasmsLeptin receptorbusiness.industryLeptinCarcinoma Ductal BreastReceptor Cross-Talklcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaseImmunohistochemistryGene Expression Regulation NeoplasticPostmenopauseEndocrinologyOncologyImmunohistochemistryReceptors LeptinFemaleSignal transductionbusinessImmunostainingProtein BindingResearch ArticleBMC cancer
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Lexicographical treatment of some forestry terms in "De la siembra y plantíos de árboles" (1773) by Casimiro Gómez Ortega.

2020

La ausencia de tratados completos sobre silvicultura en la España del siglo xviii se suplió en parte con traducciones. El botánico Casimiro Gómez Ortega publicó en 1773 la traducción de la obra del agrónomo Duhamel du Monceau Des semis et plantations des bois (1760). En este artículo, estudiaremos 19 términos propios de esta disciplina desde un punto de vista lexicográfico comparando las definiciones en distintos diccionarios y en el glosario incluido en la obra origen y en la traducción. Constataremos que, a pesar de la falta de estudios publicados, gran parte de los términos ya estaban normalizados en los diccionarios de la época The absence of comprehensive treatises on forestry in 18th …

Lexicographylcsh:P101-41018th centuryLingüísticaSiglo XVIIIHistory of translationPhilosophyForestryLexicografíasiglo xviiisilviculturalcsh:Language. Linguistic theory. Comparative grammarlcsh:Philology. LinguisticsAnesthesiology and Pain Medicinelcsh:P1-1091lcsh:PC1-5498lcsh:Romanic languagesHistoria de la traducciónSilviculturahistoria de la traducciónHumanitieslexicografía:8- Lingüística y literatura [CDU]
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Understanding and exploiting long-lived near-infrared emission of a molecular ruby

2018

Coordination chemistry reviews 359, 102 - 111 (2018). doi:10.1016/j.ccr.2018.01.004

Ligand field theory010405 organic chemistryChemistryMetal ions in aqueous solutionNear-infrared spectroscopyRelaxation (NMR)chemistry.chemical_element010402 general chemistryPhotochemistry54001 natural sciences0104 chemical sciencesInorganic ChemistryChromiumExcited stateddc:540Materials ChemistryMoleculePhotosensitizerPhysical and Theoretical Chemistry
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