Search results for "58"
showing 10 items of 2229 documents
Työkulttuurien jännitteitä koulutusyhteisöissä
2019
Tarkastelemme artikkelissa jännitteitä koulutusyhteisöjen työkulttuureissa. Lähestymme aihetta opettajankoulutuksen kehittämiseen orientoituneesta koulutusmallista valmistuneiden opettajien kokemusten avulla. Tutkimuksen empiirisenä aineistona on 13 puolistrukturoitua yksilöhaastattelua, jotka kerättiin koulutusmalliin osallistuneilta opettajilta. Teoriasidonnaisessa sisällönanalyysissa keskityttiin yhteisön työkulttuuriin etsien myös sen vaikeammin havaittavia elementtejä, Scheinin (2017) sanoin perusolettamuksia.
 Tarkastelemme, miten yhteisöllisen ja kriittistä ammatillisuutta tukevan koulutusmallin anti on koettu ja miten sen vaikutukset ovat näyttäytyneet työelämässä. Tutkimuksemm…
Constant sign and nodal solutions for parametric anisotropic $(p, 2)$-equations
2021
We consider an anisotropic ▫$(p, 2)$▫-equation, with a parametric and superlinear reaction term.Weshow that for all small values of the parameter the problem has at least five nontrivial smooth solutions, four with constant sign and the fifth nodal (sign-changing). The proofs use tools from critical point theory, truncation and comparison techniques, and critical groups. Spletna objava: 9. 9. 2021. Abstract. Bibliografija: str. 1076.
Social Media as Platform for Stimulating Urban Changes
2016
Images have always been an important part of city planning – current images of place, images with planned improvements, maps and sketches. Some time ago all that was a private property of stakeholders like planner and client. But nowadays this confidentiality rather much has vanished – no copyrights or competition is noteworthy. Plans do not have their privacy anymore. They are exposed even before they got implemented. This article will display why city planners share the images of their ideas, of their dreams in public (mostly in blogs and social networks) – why it is important for them and what kind of feedback they are waiting for. This article is based on case study where 12 respondents…
Postveritat, escepticisme de recepció i escepticisme d'emissió
2019
Les creences porten a l'acció i en l'acció es manifesten. Actuem segons allò que creiem, i no sempre les nostres creences constitueixen coneixement. Són les creences les que ens menen (atesos uns desitjos determinats) a actuar, i com que aquestes poden ser falses, els nostres intents de vegades es veuen -per aquesta raó- frustrats: les nostres accions no assoleixen l'èxit. En la mesura que les nostres accions afecten altres persones, creences errònies poden dur a cometre injustícies, perjudicis o danys. Per tot això és important formar i transmetre creences vertaderes. Per totes aquestes raons, com a agents epistèmics i també morals, hem de procurar ser fiables a l'hora de formar les nostre…
La segunda operación del intelecto según santo Tomás de Aquino
2013
De acuerdo con la teoría del conocimiento de santo Tomás de Aquino, el juicio se parece a un fin en el proceso intelectivo iniciado por la simple aprehensión. La segunda operación del intelecto es necesaria para conocer la verdad como adecuación “intelletus et rei” y como carácter extramental del objeto conocido con la primera operación, de manera tal que se pueda decir que el juicio es “generador” de las fronteras entre Aristóteles y el “ens ut verum” de Aquino.
CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreati…
2021
Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of the family Picornaviridae and can cause acute acinar pancreatitis in adults. However, the molecular mechanisms of pathogenesis underlying CVB3-induced acute pancreatitis have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation and exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, and confocal microscopy, we show that Menage a trois 1 (MAT1), a subunit of the Cdk-Activating Kinase (CAK) complex involved in cell proliferation and transcription, is a novel interaction protein with CVB3 VP1. Moreover, CVB3 VP1 inhibited MAT…
Infection-induced chromatin modifications facilitate translocation of herpes simplex virus capsids to the inner nuclear membrane
2021
Herpes simplex virus capsids are assembled and packaged in the nucleus and move by diffusion through the nucleoplasm to the nuclear envelope for egress. Analyzing their motion provides conclusions not only on capsid transport but also on the properties of the nuclear environment during infection. We utilized live-cell imaging and single-particle tracking to characterize capsid motion relative to the host chromatin. The data indicate that as the chromatin was marginalized toward the nuclear envelope it presented a restrictive barrier to the capsids. However, later in infection this barrier became more permissive and the probability of capsids to enter the chromatin increased. Thus, although …
Immune responses during COVID-19 infection
2020
International audience; Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV (SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and 2015, and SARS-CoV-2 in 2020, have been causing severe and fatal human epidemics. The unpredictability of coronavirus disease-19 (COVID-19) poses a major burden on health care and economic systems across the world. This is caused by the paucity of in-depth knowledge of the risk factors for severe COVID-19, insufficient diagnostic tools for the detection of SARS-CoV-2, as well as the absence of specific and effective drug treatments. While protective humoral and cellular immune responses are usually m…
Building a political image on Instagram: A study of the personal profile of Santiago Abascal (Vox) in 2018
2020
Due to Instagram’s growing popularity in Spain, politicians have also begun to turn to this social network increasingly more. Accordingly, this paper analyses the visual and textual discourse of 259 posts published throughout 2018 on the personal Instagram profile of Santiago Abascal, the leader of the party Vox. Insofar as he is the Spanish politician with the highest number of followers on Instagram, the aim here is to analyse how he uses this social network in order to identify possible strategies that justify his growing number of followers. In the analysis, special attention was paid to aspects that might have contributed to the (self)presentation of Abascal and the promotion of his pa…
Motion perception in early glaucoma
2013
Purpose: The aim of our study was to underline the changes in the movement perception for early glaucoma. Our working hypothesis consisted in inquiring if the impairment of the magnocellular pathway may modify the movement perception capabilities in the visual field, more particularly in its peripheral area.Methods: We included 14 healthy subjects and 14 patients with early primary open angle glaucoma. A moving target was presented on a semicircular screen (1.8 m diameter); participants were asked to localize the Ending Point (EP) of each movement. Each stimulus consisted in a white dot (0,72° of diameter) moving horizontally with the imposed velocity profile. Two different laws of motion w…