Search results for "616"
showing 10 items of 335 documents
Omalizumab rapidly improves angioedema-related quality of life in adult patients with chronic spontaneous urticaria: X-ACT study data
2018
Background The X-ACT study aims to examine the effect of omalizumab treatment on quality of life (QoL) in chronic spontaneous urticaria (CSU) patients with angioedema refractory to high doses of H1-antihistamines. Methods In X-ACT, a phase III, double-blind, placebo-controlled study, CSU patients (18–75 years) with ≥4 angioedema episodes during the 6 months before inclusion were randomized (1:1) to receive omalizumab 300 mg or placebo every 4 weeks for 28 weeks. Angioedema-related QoL, skin-related QoL impairment, and psychological well-being were assessed. Results Ninety-one patients were randomized and 68 (omalizumab, n=35; placebo, n=33) completed the 28-week treatment period. At baselin…
Development and Validation of a Scale to Measure Caregiver Skills in Eating Disorders
2015
Objective: The aim of this study was to develop and validate a new ques- tionnaire designed to measure caregiver skills that, in line with the interperso- nal component of the cognitive inter- personal maintenance model (Schmidt and Treasure, J Br J Clin Psychol, 45, 343–366, 2006), may be helpful in the support of people with anorexia nerv- osa (AN). A further aim is to assess whether this scale is sensitive to change following skills-based caregiver interventions. Method: The Caregiver Skills (CASK) scale was developed by a group of clinicians and caregivers. Preliminary versions of the scale devised for both caregivers and parents were given at baseline and at follow-up after two studies…
The global impact of the COVID-19 pandemic on the management and course of chronic urticaria
2021
Introduction: the COVID-19 pandemic dramatically disrupts health care around the globe. The impact of the pandemic on chronic urticaria (CU) and its management are largely unknown. Aim: to understand how CU patients are affected by the COVID-19 pandemic; how specialists alter CU patient management; and the course of CU in patients with COVID-19. Materials and methods: our cross-sectional, international, questionnaire-based, multicenter UCARE COVID-CU study assessed the impact of the pandemic on patient consultations, remote treatment, changes in medications, and clinical consequences. Results: the COVID-19 pandemic severely impairs CU patient care, with less than 50% of the weekly numbers o…
Estudio "in vitro" del efecto sobre la permeabilidad de la dentina de 4 sistemas adhesivos propuestos para el tratamiento de la sensibilidad dentinar…
2007
La sensibilidad dentinaria (SD) es un problema frecuente en la consulta dental. Se define como el dolor que surge de la dentina expuesta, de manera característica como reacción a estímulos químicos, térmicos, táctiles u osmóticos, que no es posible explicar como surgidos de algún otro defecto o trastorno dental.Varias teorías han sido propuestas para explicar la aparición del dolor. La más aceptada actualmente es la Teoría Hidrodinámica, según esta, el movimiento del fluido contenido en los túbulos dentinarios es el responsable de estimular las fibras nerviosas pulpares, produciendo así el dolor característico de la SD. Los adhesivos dentinarios se encuentran dentro de las opciones más mode…
Narrativity and intertextuality in the making of a shared European memory
2016
The latest wave of European integration process, cultural Europeanization, includes complex processes, such as the attempts to create a shared European memory that would transcend national interpretations of the past. The cultural Europeanization can be perceived as a narrative operation: in it the EU, Europe, and Europeanness are given meanings and made sense of through narrativization. The article investigates the EU’s attempts to create a shared European memory by analyzing the exhibition narrative of the Parlamentarium, the visitors’ center of the European Parliament. The analysis indicates how the construction of an official shared European memory is operationalized through textual and…
Evaluation of the iridocorneal angle with accommodation using optical coherence tomography
2017
The changes in the iridocorneal angle structure during accommodation are assessed by means of anterior segment optical coherence tomography. Thirteen right eyes were included in the study. The device used for the measurement was the Visante® omni system. The stimuli were set up at different vergences (0.0 D, -1.5 D, and -3.0 D). The angle opening distance 500 and 750, the trabecular iris space area 500 and 750, and the scleral spur angle parameters were assessed at the nasal and temporal regions. The results in the iridotrabecular angle comparing the three accommodative states of the eye did not yield any statistically significant difference at nasal or temporal angle sections. In light of …
Prevalencia de signos y síntomas de DCM en un grupo de niños de 6 a 12 años.
2008
Este estudio tiene como objetivo estimar la prevalencia de signos y síntomas de disfuncióncraneomandibular (DCM) en un grupo de niños de 6 a 12 años de edad de Valencia.El método utilizado fue: anamnesis, cuestionario a los padres y examen clínico.Los resultados revelaron que:Un 54,6% de los niños y el 66% de las niñas presentaron al menos un síntoma de DCM:dolor de cabeza, dolor en los oídos, boca desencajada, ruidos al masticar, dificultad al masticar.Un 82,8% de los niños y el 87,5% de las niñas tenían al menos un hábito o parafunción:rechinar, morderse las uñas, chuparse los dedos, morder lápiz o bolígrafo, roncar, masticaciónunilateral, dormir con la boca abierta, empuje lingual, deglu…
Thinking about movement hurts: The effect of motor imagery on pain and swelling in people with chronic arm pain
2008
Objective: Chronic painful disease is associated with pain on movement, which is presumed to be caused by noxious stimulation. We investigated whether motor imagery, in the absence of movement, increases symptoms in patients with chronic arm pain. Methods: Thirty‐seven subjects performed a motor imagery task. Pain and swelling were measured before, after, and 60 minutes after the task. Electromyography findings verified no muscle activity. Patients with complex regional pain syndrome (CRPS) were compared with those with non‐CRPS pain. Secondary variables from clinical, psychophysical, and cognitive domains were related to change in symptoms using linear regression. Results: Motor imagery in…
Harmonized benchmark labels of the hippocampus on magnetic resonance: The EADC-ADNI project
2015
Abstract Background A globally harmonized protocol (HarP) for manual hippocampal segmentation based on magnetic resonance has been recently developed by a task force from European Alzheimer's Disease Consortium (EADC) and Alzheimer's Disease Neuroimaging Initiative (ADNI). Our aim was to produce benchmark labels based on the HarP for manual segmentation. Methods Five experts of manual hippocampal segmentation underwent specific training on the HarP and segmented 40 right and left hippocampi from 10 ADNI subjects on both 1.5 T and 3 T scans. An independent expert visually checked segmentations for compliance with the HarP. Descriptive measures of agreement between tracers were intraclass cor…