Search results for "65"
showing 10 items of 1111 documents
A Coupled Fixed Point Theorem in Fuzzy Metric Space Satisfying ϕ-Contractive Condition
2013
The intent of this paper is to prove a coupled fixed point theorem for two pairs of compatible and subsequentially continuous (alternately subcompatible and reciprocally continuous) mappings, satisfyingϕ-contractive conditions in a fuzzy metric space. We also furnish some illustrative examples to support our results.
Sharpness of Rickman’s Picard theorem in all dimensions
2015
We show that given \({n \geqslant 3}\), \({q \geqslant 1}\), and a finite set \({\{y_1, \ldots, y_q \}}\) in \({\mathbb{R}^n}\) there exists a quasiregular mapping \({\mathbb{R}^n\to \mathbb{R}^n}\) omitting exactly points \({y_1, \ldots, y_q}\).
Activation of TRPC6 calcium channels by diacylglycerol (DAG)-containing arachidonic acid: A comparative study with DAG-containing docosahexaenoic acid
2006
We synthesized a diacylglycerol (DAG)-containing arachidonic acid, i.e., 1-stearoyl-2-arachidonyl-sn-glycerol (SAG), and studied its implication in the modulation of canonical transient receptor potential sub-type 6 (TRPC6) channels in stably-transfected HEK-293 cells. SAG induced the influx of Ca(2+), and also of other bivalent cations like Ba(2+) and Sr(2+), in these cells. SAG-evoked Ca(2+) influx was not due to its metabolites as inhibitors of DAG-lipase (RHC80267) and DAG-kinase (R50922) failed to inhibit the response of the same. To emphasise that SAG exerts its action via its DAG configuration, but not due to the presence of stearic acid at sn-1 position, we synthesized 1-palmitoyl-2…
Documentário ficcional e responsabilidade social: a recriação da violência de gênero na televisão
2020
espanolO tratamento da violencia de genero tem experimentado uma notavel mudanca nos meios de comunicacao espanhois nas ultimas duas decadas. Propiciada pela conscientizacao e pela publicacao de codigos eticos, essa evolucao e caracterizada por abandonar o discurso que delimitava a violencia contra as mulheres na cronica de acontecimentos para aborda-la em sua dimensao de problema social com causas estruturais. Contudo, os avancos na cobertura informativa contrastam com o surgimento de modelos de docuficcao, que combinam o depoimento das vitimas e seu contexto com reconstrucoes ficcionais. Esta pesquisa tem como objetivo indagar o tratamento que esses modelos oferecem, a partir da analise d…
Historia de la Provincia del Santisimo Rosario de Filipinas, China, y Tunquin Orden de Predicadores : Quarta parte desde el año de 1700 hasta el de …
1783
Caplletres grav. i vinyetes Sign.: [ ]1, 23 [ ]2, a-dddddddd2 Port. amb orla xil. Reclams
Historia de la Provincia del Santisimo Rosario de Filipinas, China, y Tunquin Orden de Predicadores : Quarta parte desde el año de 1700 hasta el de 1…
Caplletres grav. i vinyetes Sign.: [ ]1, 23 [ ]2, a-dddddddd2 Port. amb orla xil Reclams
Core-crosslinked polymeric micelles: Principles, preparation, biomedical applications and clinical translation
2015
Polymeric micelles (PM) are extensively used to improve the delivery of hydrophobic drugs. Many different PM have been designed and evaluated over the years, and some of them have steadily progressed through clinical trials. Increasing evidence suggests, however, that for prolonged circulation times and for efficient EPR-mediated drug targeting to tumors and to sites of inflammation, PM need to be stabilized, to prevent premature disintegration. Core-crosslinking is among the most popular methods to improve the in vivo stability of PM, and a number of core-crosslinked polymeric micelles (CCPM) have demonstrated promising efficacy in animal models. The latter is particularly true for CCPM in…
Functionalized Poly(N-isopropylacrylamide)-Based Microgels in Tumor Targeting and Drug Delivery
2021
Over the past several decades, the development of engineered small particles as targeted and drug delivery systems (TDDS) has received great attention thanks to the possibility to overcome the limitations of classical cancer chemotherapy, including targeting incapability, nonspecific action and, consequently, systemic toxicity. Thus, this research aims at using a novel design of Poly(N-isopropylacrylamide) p(NIPAM)-based microgels to specifically target cancer cells and avoid the healthy ones, which is expected to decrease or eliminate the side effects of chemotherapeutic drugs. Smart NIPAM-based microgels were functionalized with acrylic acid and coupled to folic acid (FA), targeting the f…
"Table 6" of "Cross-sections and leptonic forward-backward asymmetries from the Z0 running of LEP."
2000
Cross section and forward-backward asymmetry in the E+ E- channel for the 1995 data. The polar angle is 44 to 136 degrees. Additional systematic error for cross section of 0.52 PCT (efficiencies and backgrounds) and 0.14 PCT (absolute luminosity). Additional systematic error for the asymmetry of 0.0020.
"Table 1" of "Study of $e^+e^- \rightarrow p\bar{p}$ in the vicinity of $\psi(3770)$"
2014
Summary of results at center-of-mass energies from 3.65 to 3.90 GeV. N(SIG) is the number of E+ E- --> P P events; EPSILON is the detection efficiency; L is the integrated luminosity; (1 + DELTA)(DRESSED) is the initial state radiation correction factor without the vacuum polarization correction; and SIG(OBS), SIG(DRESSED) and SIG(BORN) are the observed cross section, the dressed cross section and the Born cross section, respectively.