Search results for "AA"
showing 10 items of 16992 documents
Baltu filoloģija, 23. sēj., Nr.2
2015
On the Difference Between Necessary and Unnecessary Glances Away From the Forward Roadway : An Occlusion Study on the Motorway
2019
Objective The present study strove to distinguish traffic-related glances away from the forward roadway from non-traffic-related glances while assessing the minimum amount of visual information intake necessary for safe driving in particular scenarios. Background Published gaze-based distraction detection algorithms and guidelines for distraction prevention essentially measure the time spent looking away from the forward roadway, without incorporating situation-based attentional requirements. Incorporating situation-based attentional requirements would entail an approach that not only considers the time spent looking elsewhere but also checks whether all necessary information has been sampl…
Multitasking in Driving as Optimal Adaptation Under Uncertainty
2021
Objective The objective was to better understand how people adapt multitasking behavior when circumstances in driving change and how safe versus unsafe behaviors emerge. Background Multitasking strategies in driving adapt to changes in the task environment, but the cognitive mechanisms of this adaptation are not well known. Missing is a unifying account to explain the joint contribution of task constraints, goals, cognitive capabilities, and beliefs about the driving environment. Method We model the driver’s decision to deploy visual attention as a stochastic sequential decision-making problem and propose hierarchical reinforcement learning as a computationally tractable solution to it. The…
Safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of the novel enzyme replacement therapy avalglucosidase alfa (neoG…
2019
This multicenter/multinational, open-label, ascending-dose study (NCT01898364) evaluated safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of repeat-dose avalglucosidase alfa (neoGAA), a second-generation, recombinant acid α-glucosidase replacement therapy, in late-onset Pompe disease (LOPD). Patients ≥18 years, alglucosidase alfa naïve (Naïve) or previously receiving alglucosidase alfa for ≥9 months (Switch), with baseline FVC ≥50% predicted and independently ambulatory, received every-other-week avalglucosidase alfa 5, 10, or 20 mg/kg over 24 weeks. 9/10 Naïve and 12/14 Switch patients completed the study. Avalglucosidase alfa was well-tolerated; no deaths…
Diffusion of Drone Journalism: the Case of Finland, 2011-2020
2020
This article details Finnish news organizations’ adoption of drones for journalistic purposes from 2011 to 2020. The theoretical starting point of the article is Rogers’ (1962) diffusion of innovations theory, which explains how new ideas and technologies spread in societies. The main empirical data for the study were derived from a phone survey conducted among the 80 most popular newspapers in Finland. The findings reveal that drone journalism in Finland has already diffused from a few pioneering organizations to a large number of newsrooms, including regional, mid-sized newspapers. Most of the newspapers are either using in-house drones, buying commissioned images, or using both strategie…
Fermionic superfluidity in optical lattices
2008
Association Between Implementation of the Athlete Biological Passport and Female Elite Runners’ Performance
2020
The purpose of this research was to evaluate the performances of female middle- and long-distance runners before and after the implementation of a new antidoping strategy (the Athlete Biological Passport [ABP]) in a country accused of systematic doping. A retrospective analysis of the results of Russian National Championships from 2008 to 2017 was performed. The 8 best female performances for the 800-m, 1500-m, 3000-m steeplechase, 5000-m, and 10,000-m events from the semifinals and finals were analyzed. The yearly number of athletes fulfilling standard qualifications for international competitions was also evaluated. Overall, numbers of athletes banned for doping in 2008–2017 were calculat…
Separazione della beta-N-metilammino-L-alanina (BMAA) in campioni di liquor cefalorachidiano mediante HPLC con rilevazione fluorimetrica
2011
Obesity and Outcomes in COVID-19: When an Epidemic and Pandemic Collide.
2020
Obesity has reached epidemic proportions in the United States and in much of the westernized world, contributing to considerable morbidity. Several of these obesity-related morbidities are associated with greater risk for death with coronavirus disease 2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 penetrates human cells through direct binding with angiotensin-converting enzyme 2 receptors on the cell surface. Angiotensin-converting enzyme 2 expression in adipose tissue is higher than that in lung tissue, which means that adipose tissue may be vulnerable to COVID-19 infection. Obese patients also have worse outcomes with COVID-19 infection, including respiratory failure, n…