Search results for "ACR"

showing 10 items of 6355 documents

Il complesso parrocchiale di San Gregorio a Cannatello (Agrigento)

2012

Nell'ambito dell'inchiesta che il "Giornale dell'Architettura" conduce sulla realizzazione de "Le chiese della Chiesa" a 50 anni dal Concilio Vaticano II, la rivista segnala quattro recenti progetti, sia italiani che di altre nazioni europee. Tra questi la Chiesa di San Gregorio ad Agrigento, della cui architettura contemporanea viene sinteticamente illustrato il progetto e documentata la sua realizzazione.

Settore ICAR/14 - Composizione Architettonica E UrbanaProgetto chiesa architettura sacra
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Effect of two distinct implant macro-designs on the osseointegration of bicortically installed implants in two topographic sites. A histomorphometric…

2019

Antecedentes científicos y objetivos de estudio: El uso de implantes dentales como alternativa para la rehabilitación oral ha demostrado su eficacia y mostrando altas tasas de supervivencia. Un aspecto clave de la osteointegración del implante dental está relacionado con la obtención de una estabilidad primaria adecuada, asegurada por el enclavamiento mecánico entre el tejido óseo y la interfaz del implante, la cual depende en parte de la geometría del implante, la rugosidad de la superficie y la técnica quirúrgica para la preparación del lecho implantario. Varios factores están involucrados en la interacción entre la superficie del implante y el hueso nativo circundante durante la osteoint…

submerged healingdental implantimplant macro-designbicortical stabilizationUNESCO::CIENCIAS MÉDICASosseointegration:CIENCIAS MÉDICAS [UNESCO]animal study
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Covid-19 : quel bilan critique ? (Partie II)

2021

International audience

SantéDonnéesGouvernementScienceCrise sanitaireAnalyseEmmanuel Macron[SHS.SCIPO]Humanities and Social Sciences/Political scienceGestionEconomieMinistère de la santéFranceCovid-19Politique[SHS.SCIPO] Humanities and Social Sciences/Political scienceComputingMilieux_MISCELLANEOUSConfinement
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Screening for Solute Transporters in Plant Photosynthetic Membranes

2008

As compared to chloroplast envelope transporters, the field of thylakoid transporters is largely unexplored. There is evidence for several transport activities in the plant thylakoid membrane, but only a copper P-type ATPase and an ATP/ADP carrier have been so far identified at the gene level in Arabidopsis thaliana. Using in silico analyses, we have predicted the existence of approximately 15 thylakoid transporters, including phosphate transporters and cation channels. For experimental validation, we have used peptide- specific antibodies and functional analyses in heterologous system. These novel data are highly relevant to understand the transport network of the thylakoid membrane and it…

biologyChemistryIn silicoATPasefood and beveragesTransportermacromolecular substancesbiology.organism_classificationChloroplast membraneChloroplastMembraneThylakoidBiophysicsbiology.proteinArabidopsis thaliana
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Über die Synthese von o-Acylamino-β-dimethylamino-propiophenonen 2. Mitt.: Aminomethylierung von o-Carbäthoxyamino- und o-Nitro-acetophenon1)

1970

Die bei der Mannich-Reaktion mit o-Carbathoxyamino- und o-Nitro-acetophenon zu Acrylophenonderivaten fuhrende Sekundarreaktion zwischen den Aminomethylierungsprodukten und Formaldehyd konnte auf folgende Weise nahezu vollstandig vermieden werden: durch Verhindern des Zerfalls von intermediar entstehendem Dimethylaminomethylol in seine Komponenten wird die Bildung des Carbonium-Imonium-Kations derart beschleunigt, das fur die Nebenreaktion erforderlicher freier Formaldehyd rasch aus dem Reaktionsmedium verschwindet. — Die Synthese von o-Carbathoxyamino-, o-Nitro- und o-Amino-β-dimethylamino-propiophenon sowie seines Formyl- und Acetylderivates wird beschrieben. Synthesis of o-Acylamino-β-dim…

chemistry.chemical_compoundAcrylophenoneChemistryDrug DiscoveryFormaldehydePharmaceutical ScienceMedicinal chemistryArchiv der Pharmazie
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Synthesis of hyperbranched poly(tert-butyl acrylate) by self-condensing atom transfer radical polymerization of a macroinimer

2000

Using 2-hydroxyethyl α-bromoisobuty-rate as initiator, atom transfer radical polymerization (ATRP) of tert-butyl acrylate leads to poly(tert-butyl acrylate) (PtBA) with a hydroxyl group at one and a bromine atom at the other end. Esterification of the hydroxyl group of these heterotelechelic polymers with acryloyl chloride yields PtBA (M n = 3060) with a polymerizable double bond at one end and a bromine atom at the other end which can act as an initiator in ATRP (macroinimer). Self-condensing ATRP of such a macroinimer leads to hyperbranched or highly branched PtBA. The polymer was characterized by GPC viscosity measurements. Even at M w = 78800, a rather low polydispersity index of M w M …

chemistry.chemical_classificationAcrylateTelechelic polymerPolymers and PlasticsDouble bondBulk polymerizationAtom-transfer radical-polymerizationOrganic ChemistryRadical polymerizationAcryloyl chloridechemistry.chemical_compoundEnd-groupchemistryPolymer chemistryMaterials ChemistryMacromolecular Rapid Communications
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Mechanism of anionic polymerization of methyl methacrylate in the presence of aluminium alkyls

1995

Methyl methacrylate was polymerized with tert-butyl lithium in the presence of triethylaluminium or triisobutylaluminium at 78°C in toluene. As indicated by GPC and MALDI-TOF mass spectrometry, the polymerization is accompanied by side reactions. The lower oligomers were fractionated by distillation and characterised by NMR, FT-IR, UV and electron impact (EI) mass spectrometry. All these data show that part of the polymer chains are carrying exactly one tert-butyl isoprenyl ketone unit. In order to avoid the formation of tert-butyl isoprenyl ketone a molar ratio of Al/Li>2 is necessary.

chemistry.chemical_classificationKetonePolymers and PlasticsChemistryOrganic ChemistryCondensed Matter PhysicsMethacrylateToluenechemistry.chemical_compoundAnionic addition polymerizationTriethylaluminiumPolymerizationPolymer chemistryMaterials ChemistryMethyl methacrylateTriisobutylaluminiumMacromolecular Symposia
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Phenotypic analysis of individuals with Costello syndrome due to HRAS p.G13C.

2011

Costello syndrome is characterized by severe failure-to-thrive, short stature, cardiac abnormalities (heart defects, tachyarrhythmia, and hypertrophic cardiomyopathy (HCM)), distinctive facial features, a predisposition to papillomata and malignant tumors, postnatal cerebellar overgrowth resulting in Chiari 1 malformation, and cognitive disabilities. De novo germline mutations in the proto-oncogene HRAS cause Costello syndrome. Most mutations affect the glycine residues in position 12 or 13, and more than 80% of patients share p.G12S. To test the hypothesis that subtle genotype-phenotype differences exist, we report the first cohort comparison between 12 Costello syndrome individuals with p…

AdultHeart Defects CongenitalMalemedicine.medical_specialtyAdolescentrasopathy.RASopathyShort statureProto-Oncogene MasArticleProto-Oncogene Proteins p21(ras)Young AdultGermline mutationSettore MED/38 - Pediatria Generale E SpecialisticaCostello syndromePregnancyInternal medicineNeoplasmsGeneticsMedicineHumansHRASChildGenetics (clinical)business.industryloose anagen hairCostello SyndromeMacrocephalyHypertrophic cardiomyopathyBrainInfantgenotype–phenotype correlationmedicine.diseaseDermatologyMagnetic Resonance ImagingMusculoskeletal AbnormalitiesEndocrinologyPhenotypeChild PreschoolFaceMutationFemalemedicine.symptombusinessMultifocal atrial tachycardiaAmerican journal of medical genetics. Part A
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In vitro fusion of phagosomes with different endocytic organelles from J774 macrophages.

1998

We describe novel biochemical and electron microscopy assays to investigate in vitro fusion of latex bead phagosomes with three different endocytic organelle fractions from J774 macrophages. After formation, early phagosomes fuse avidly with early and late endosomes and for a longer period of time with lysosomes, but they subsequently become fusion-incompetent. The fusion of early, but not late, phagosomes with all three endocytic fractions could be significantly stimulated by Rab5. In contrast to other cell types investigated, this Rab is uniquely enriched on both early and late endosomes in J774 macrophages. Moreover, exogenous Rab5 stimulates homotypic fusion between both sets of organel…

Cell typeEndosomeMacrophagesEndocytic cycleCell BiologyBiologyBiochemistryIn vitroEndocytosisCell biologyCell LineCell FusionMiceCricetinaePhagosomesOrganelleAnimalsHumansRabMolecular BiologyFusion mechanismPhagosomeThe Journal of biological chemistry
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The interleukin (IL)-31/IL-31R axis contributes to tumor growth in human follicular lymphoma

2014

Interleukin (IL)-31A binds to an heterodimer composed of IL-31 receptor A (IL-31RA) and Oncostatin M Receptor (OSMR). The IL-31/IL-31R complex is involved in the pathogenesis of various skin diseases, including cutaneous T-cell lymphoma. No information is available on the relations between the IL-31/IL-31R complex and B-cell lymphoma. Here we have addressed this issue in follicular lymphoma (FL), a prototypic germinal center(GC)-derived B-cell malignancy. IL-31 enhanced primary FL cell proliferation through IL-31R-driven signal transducer and activator of transcription factor 1/3 (STAT1/3), extracellular signal-regulated kinase 1/2 (ERK1/2) and Akt phosphorylation. In contrast, GC B cells d…

MaleSTAT3 Transcription Factormedicine.medical_specialtyCancer ResearchPrimary Cell CultureFollicular lymphomaBiologyParacrine signallingCytosolCell-Derived MicroparticlesInternal medicinemedicineHumansProtein IsoformsPhosphorylationAutocrine signallingLymphoma FollicularCell ProliferationMitogen-Activated Protein Kinase 1B-LymphocytesMitogen-Activated Protein Kinase 3Gene Expression Regulation LeukemicInterleukinsMicrovesicleMedicine (all)Cell MembraneB-LymphocyteGerminal centerOncostatin M receptorInterleukinProtein IsoformReceptors InterleukinHematologyInterleukinMiddle Agedmedicine.diseaseGerminal CenterMolecular biologyCell-Derived MicroparticleEndocrinologySTAT1 Transcription FactorAnesthesiology and Pain MedicineOncologyFemaleSignal transductionNeoplasm GradingProto-Oncogene Proteins c-aktHumanSignal Transduction
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