Search results for "AH"
showing 10 items of 6917 documents
The relation between workload and personal well-being among university professors
2019
The aim of the present study was to explore the level of perceived workload of university professors and to evaluate related psychosocial risks, such as addiction to work, psychological distress, and work–life conflicts. A total of 252 professors, balanced for gender (Mean age = 48.1; DS: 5.1) from 10 different universities across Europe participated in the research. Participants completed the University’s Work Environment Survey, the Dutch Workaholism Scale, and The General Health Questionnaire. The results showed that workload, when linked to bureaucratic university practices, is a predisposing factor to a negative perception of work-related well-being among university professors.
Reformācija un bērnu kristības
2018
Bakalaura darba nosaukums ir “Reformācija un bērnu kristības.” Bakalaura darbs pēta vai teologa Frīdriha Šleiermahera izvirzītais arguments par to, ka bērnu kristības līdz ar Reformāciju vajadzētu atcelt sakrīt ar moderno teologu viedokli. Kā darba tēze izvirzīts apgalvojums, ka modernie teologi nepievienojas Šleiermahera ieskatam par bērnu kristību atcelšanu līdz ar Reformāciju. Pētījuma struktūru sastāda trīs nodaļas (ar apakšnodaļām), kuras ir veidotas atbilstoši izvirzītajiem darba uzdevumiem. Pirmajā nodaļā tiek apskatīts kristību jēdziens, tā vēsturiskā nozīme un pašu kristību priekšnosacījumi. Otrajā nodaļā apskatīta Frīdriha Šleiermahera nostāja kristību un bērnu kristību jautājumā.…
Laboratorisko iekaisuma marķieru prognostiskā nozīme nozokomiālās infekcijas diagnostikā smagas termiskas apdeguma traumas pacientam
2017
Darba pamatojums. Zelta standarts intrahospitālās infekcijas un sepses diagnostikā, pacientiem ar apdeguma traumu, vēl joprojām balstās uz mikrobioloģisko izmeklēšanu, kura var aizkavēt antibakteriālas terapijas uzsākšanas laiku. Līdz ar to ir mērķtiecīgi atrast prognostisko faktoru, kurš var agrīni norādīt uz intrahospitālas infekcijas attīstību, pacientiem ar smagu apdeguma traumu. Izvirzītā hipotēze: laboratoriskie radītāji var agrīni norādīt uz draudošo intrahospitālas infekcijas attīstību, pacientiem ar smagu termisku apdeguma traumu. Materiāli un metodes. Pētījums norisinājās RAKUS stacionārā “Biķernieki”, Valsts apdeguma centrā. Pētījumā tika iekļauti pacienti, kuri guvuši smagu term…
Cannabis and the Mesolimbic System
2016
Abstract Cannabis sativa (hemp) is a flowering annual plant whose phytochemical by-products, hashish and marihuana, are the most widely produced and most frequently used illicit drugs in Europe. Δ 9 -Tetrahydrocannabinol is the primary psychoactive constituent, responsible, in a dose-related manner, for euphoria, cognitive effects, and psychotic symptoms, as well as the addictive potential of smoked cannabis due to its interference with the mesolimbic dopaminergic system. Cannabis as well as endocannabinoids acts mainly at the presynaptic levels in several brain regions, including the nucleus accumbens and ventral tegmental area, where it modulates synaptic activity. Through the modulation …
Decreasing dietary linoleic acid promotes long chain omega-3 fatty acid incorporation into rat retina and modifies gene expression
2011
International audience; Age-related macular degeneration (AMD) may be partially prevented by dietary habits privileging the consumption of ω3 long chain polyunsaturated fatty acids (ω3s) while lowering linoleic acid (LA) intake. The present study aimed to document whether following these epidemiological guidelines would enrich the neurosensory retina and RPE with ω3s and modulate gene expression in the neurosensory retina. Rat progenitors and pups were fed with diets containing low or high LA, and low or high ω3s. After scotopic single flash and 8-Hz-Flicker electroretinography, rat pups were euthanized at adulthood. The fatty acid profile of the neurosensory retina, RPE, liver, adipose tis…
SOCS3 transactivation by PPARγ prevents IL-17-driven cancer growth.
2013
Abstract Activation of the transcription factor PPARγ by the n-3 fatty acid docosahexaenoic acid (DHA) is implicated in controlling proinflammatory cytokine secretion, but the intracellular signaling pathways engaged by PPARγ are incompletely characterized. Here, we identify the adapter-encoding gene SOCS3 as a critical transcriptional target of PPARγ. SOCS3 promoter binding and gene transactivation by PPARγ was associated with a repression in differentiation of proinflammatory T-helper (TH)17 cells. Accordingly, TH17 cells induced in vitro displayed increased SOCS3 expression and diminished capacity to produce interleukin (IL)-17 following activation of PPARγ by DHA. Furthermore, naïve CD4…
Docosahexaenoic acid modulates the expression of T-bet and GATA-3 transcription factors, independently of PPARα, through suppression of MAP kinase ac…
2009
The present study was conducted on CD4(+) T cells, isolated from wild type (WT) and PPARalpha(null) mice, in order to assess the mechanism of action of docosahexaenoic acid (DHA), an n-3 fatty acid, in the modulation of two transcription factors, i.e., T-bet and GATA-3, implicated in T-cell differentiation towards, respectively, T(H)1 and T(H)2 phenotype. The T-cells from PPARalpha(null) mice secreted higher IFN-gamma and lower IL-4 concentrations than WT T-cells. Furthermore, the deletion of PPARalpha gene in T-cells resulted in the upregulation of T-bet and downregulation of GATA-3 both at mRNA and protein levels. DHA exerted not only an inhibitory effect on T-cell proliferation, but also…
BRIMA : Low-Overhead Browser-Only Image Annotation Tool
2021
Image annotation and large annotated datasets are crucial parts within the Computer Vision and Artificial Intelligence fields. At the same time, it is well-known and acknowledged by the research community that the image annotation process is challenging, time-consuming and hard to scale. Therefore, the researchers and practitioners are always seeking ways to perform the annotations easier, faster, and at higher quality. Even though several widely used tools exist and the tools’ landscape evolved considerably, most of the tools still require intricate technical setups and high levels of technical savviness from its operators and crowdsource contributors.In order to address such challenges, w…
Risk perception and gratitude mediate the negative relationship between COVID-19 management satisfaction and public anxiety
2023
AbstractIn this study, we explored whether satisfaction with government management, perception of risk, and gratitude influenced public anxiety during the COVID-19 pandemic in China. Using a cross-sectional, anonymous and confidential online survey, a nationwide sample of Chinese adults (N = 876) was targeted between March 25–March 30, 2020, a period in which newly confirmed cases significantly declined in China. The anxiety level was decreased as compared to that assessed during the peak period. Multiple parallel mediation modeling demonstrated that risk perception and gratitude partially mediated the relationship between satisfaction with government management and public anxiety. Increasi…
CVG-ICP-OES -menetelmän käyttö elohopean analysointiin eläinkudoksesta
2015
Tässä Pro gradu –tutkielmassa käsitellään elohopean määritystä eläinkudoksesta kemiallinen höyryn muodostus induktiivisesti kytketty plasma optinen emissio spektrometria –menetelmällä (CVG-ICP-OES) ja siihen liittyvää näytteenkäsittelyä. Tutkimuksen kirjallisessa osassa käydään läpi muun muassa eri näytteenliuotusmenetelmiä, analyysimenetelmiä, tutkittavien metallien pelkistämistä CVG-ICP-OES –analyysiä varten ja CVG-ICP-OES –analyysissä esiintyviä häiriöitä. Näytteenliuotusosassa keskitytään pääasiassa tutkimuksessa käytetyn ultraäänihajotuksen esittelyyn, tämän lisäksi myös muita yleisiä näytteenliuotusmenetelmiä esitetään. Analyysimenetelmä osiossa suurin huomio keskittyy ICP-OES –laitte…