Search results for "AHA"

Suomessa asuvien yläkouluikäisten maahanmuuttajanuorten seksuaaliterveystiedot

2011

Opinnäytetyön tarkoituksena on selvittää millainen seksuaaliterveystietämys yläkouluikäisillä maahanmuuttajanuorilla on. Tutkimuksessa tarkastellaan iän, sukupuolen, luokka-asteen, maassaoloajan ja kouluvuosien yhteyttä seksuaaliterveystietoihin. Tutkimuksessa selvitetään myös millaista seksuaaliterveystietoa maahanmuuttajanuoret kokevat tarvitsevansa ja miten tämä on suhteessa heidän menestykseensä tietokysymyksissä. Lisäksi selvitetään maahanmuuttajanuorten kokemuksia koulun seksuaaliopetuksesta. Tutkimuksen aineisto kerättiin kyselylomakkeella, joka perustui suomalaisnuorille aiemmin tehdyn seksuaaliterveystietokyselyn kysymyksiin. Tutkimukseen osallistui viisi yläkoulua eri puolilta Suo…

Multi-professional work practices in the field of immigrant integration – examples of collaboration between the police and social work

2017

Development of the professional competences and work practices are required when promoting successful immigrant integration in a constantly diversifying society. One work method applied in this field is multi-professional collaboration. Cooperation between the authorities at the local level reduces the overlap between services and brings together expertise and resources, resulting in not only added value but also more proactive and less costly service.  Thus, collaboration can involve actors from various sectors, like NGOs or ethnic minority communities. In this article examples of collaboration in two different multi-ethnic contexts are introduced: first, in school and second, in a suburb.…

EFFETTI CITOTOSSICI SINERGICI INDOTTI DALLA COMBINAZIONE SAHA/PARTENOLIDE IN CELLULE DI CARCINOMA MAMMARIO UMANO MDA-MB231

Il Partenolide (PN) è un sesquiterpene lattone, estratto dalla pianta medicinale Tanacetum Parthenium, noto per le sue proprietà antiinfiammatorie, antimicrobiche e antitumorali. A tal proposito, recentemente è stato dimostrato che il PN è in grado di esercitare un potente effetto citotossico in cellule di “carcinoma mammario umano triplo negativo” (TNBC) MDA-MB231. Tuttavia quando il composto è impiegato a basse dosi determina effetti citotossici molto limitati, anche dopo lunghi periodi di trattamento. Questi risultati suggeriscono che il PN nelle cellule MDA-MB231 è in grado di indurre effetti citoprotettivi che si evidenziano quando impiegato a basse dosi. Poiché tale caratteristica pot…

IL TRATTAMENTO COMBINATO SAHA/TRAIL INDUCE IN CELLULE DI CARCINOMA MAMMARIO MDA-MB231 IL DISTACCO E LA MORTE PER ANOIKIS

2011

Jay Amin Hydroxamic Acid (JAHA), a histone deacetylase inhibitor with cytotoxic activity and the property to increase DNA repair of triple-negative M…

2017

Jay Amin Hydroxamic Acid (JAHA; N8-ferrocenylN1-hydroxy-octanediamide) is a ferrocene-containing analogue of the histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA). JAHA’s cytotoxic activity on MDA-MB231 triple negative breast cancer (TNBC) cells at 72 h has been previously demonstrated with an IC50 of 8.45 M. JAHA’s lethal effect was found linked to perturbations of cell cycle, mitochondrial activity, signal transduction and autophagy mechanisms. In order to glean novel insights on how MDA-MB231 breast cancer cells respond to the cytotoxic effect induced by JAHA, and to compare the biological effect with the related compound SAHA, we have employed a combination o…

NEOTECTONIC ACTIVITY AND EMISSION OF FLUIDS IN THE NORTHWEST SICILY CHANNEL

The southern Sicilian coast represents an important contribution to Italian tourism, the Sicily Channel is an important communication path because at the top of its seafloor there are many pipelines, and submarine communication cables which are laid to carry signals, and which are very important to the minor islands. In this work, we are presenting results of the detailed geomorphological and seismostratigraphic analysis based on new very high-resolution dataset (multibeam and CHIRP) acquired during the ACUSCAL 2015 Cruise. We also used low resolution bathymetric and seismic data provided from online database (ViDEPI, GEBCO, EMODnet). This study allows us to reconstruct the tectonic volcani…

Electron structure, ultra-dense hydrogen and low energy nuclear reactions

2019

In this paper, a simple Zitterbewegung electron model, proposed in a previous work, is presented from a different perspective based on the principle of mass- frequency equivalence. A geometric- electromagnetic interpretation of mass, relativistic mass, De Broglie wavelength, Proca, Klein- Gordon, Dirac and Aharonov- Bohm equations in agreement with the model is proposed. A non-relativistic, Zitterbewegung interpretation of the 3.7 keV deep hydrogen level found by J. Naudts is presented. According to this perspective, ultra-dense hydrogen can be conceived as a coherent chain of bosonic electrons with protons or deuterons located in the center of their Zitterbewegung orbits. This approach sug…

Migrazioni letterarie della parola della notte (Shaharazad, Djebar, Bufalino)

2008

Frutto di contaminazioni culturali Les Mille e una notte appaiono come un significativo esempio di prodotto interculturale che, a partire dall’adattamento in lingua francese realizzata nei primi decenni del Settecento da Antoine Galland hanno continuato ad alimentare nella cultura occidentale, successive ondate di interesse e di curiosità. Obiettivo del saggio è quello di indagare sul passaggio della struttura narrativa imbastita sulla funzione della ‘parola della notte’ che, da Les Mille e una notte trasmigra fino ad approdare a due esempi di scrittura contemporanea, identificati ne Le menzogne della notte dello scrittore siciliano Gesualdo Bufalino (1988) e Les nuits de Strasbourg (1987) …

Identidad transterritorial en la literatura saharaui: La luz de cuatro velas en el Sáhara de Ali Salem Iselmu

2022

The study focuses on the analysis of Ali Salem Iselmu's collection of short stories, La luz de cuatro velas en el Sáhara, as an expression, within Saharawi Literature, of a peculiar identity paradigm, which is based on the transterritorial experience of the author and its characters. The book is made up of four parts, four 'chronotopes', according to a journey from the past to the vision of the future. It is about the four candles that are lit to the beat of the stories that the grandfather/teacher Sidati, one night inside the tent in the camp, decides to start narrating to his granddaughter Marta, to clarify his constant doubts about his name and the two languages she speaks. The constitut…

Identidad transterritorial en la literatura saharawi: La luz de cuatro velas en el Sáhara de Ali Salem Inselmu

2022

The study focuses on the analysis of Ali Salem Iselmu’s collection of short stories, La luz de cuatro velas en el Sáhara, as an expression, within Saharawi Literature, of a peculiar identity paradigm, which is based on the transterritorial experience of the author and its characters. The book is made up of four parts, four ‘chronotopes’, according to a journey from the past to the vision of the future. The constitution in Madrid, on July 9, 2005, of the Generación de la Amistad, by a whole generation of journalists, poets, writers with roots in Western Sahara, a former Spanish colony, with a biography of a migrant and with the determination of writing a literature in Spanish with traces of …