Search results for "AIDS"
showing 10 items of 232 documents
Advantages of binaural hearing provided through bimodal stimulation via a cochlear implant and a conventional hearing aid: a 6-month comparative stud…
2005
Our study data demonstrate the additional benefit derived from continued use of a contralateral hearing aid (HA) post-cochlear implantation for speech recognition ability in quiet and in noise. Postoperative bimodal stimulation is recommended for all subjects who show some speech recognition ability in the contralateral ear as it may offer binaural listening advantages in various listening situations encountered in everyday life.To assess the benefits derived from bimodal stimulation for experienced HA users implanted with a cochlear implant (CI) (score=20% in disyllabic test). The correlation between pre- and postoperative performance on speech perception measures was examined to determine…
Effect of Rotating Auditory Scene on Postural Control in Normal Subjects, Patients With Bilateral Vestibulopathy, Unilateral, or Bilateral Cochlear I…
2018
International audience; Objective: The aim of this study was to investigate the impact of a rotating sound stimulation on the postural performances in normal subjects, patients with bilateral vestibulopathy (BVP), unilateral (UCI), and bilateral (BCD cochlear implantees.Materials and Methods: Sixty-nine adults were included (32 women and 37 men) in a multicenter prospective study. The group included 37 healthy subjects, 10 BVP, 15 UCI, and 7 BCI patients. The average of age was 47 +/- 2.0 (range: 23-82). In addition to a complete audiovestibular work up, a dynamic posturography (Multitest Framiral, Grasse) was conducted in silence and with a rotating cocktail party sound delivered by headph…
Host immune response to Cryptosporidium parvum infection
2010
Species of the genus Cryptosporidium are protozoan parasites (Apicomplexa) that cause gastroenteritis in animals and humans. Of these Cryptosporidium parvum and Cryptosporidium hominis are the major causative agents of human cryptosporidiosis. Whereas infection is self-limiting in the immunocompetent hosts, immunocompromised individuals develop a chronic, life-threatening disease. As specific therapeutic or preventive interventions are not yet available, better understanding of the immune response to the parasite is required. This minireview briefly summarizes the factors involved in the innate and acquired immune response in this pathogen-host interaction with an emphasis on more recent da…
An Efficient Synthesis of Tenofovir (PMPA): A Key Intermediate Leading to Tenofovir-Based HIV Medicines
2020
Abstract: Herein, we report further improvements to the synthesis of tenofovir 1, the precursor to tenofovir disoproxil fumarate and tenofovir alafenamide fumarate. Starting from acyclic precursor diaminomalononitrile 12, a four-step protocol to tenofovir 1 will allow for vertical integration for more manufacturers. The key transformation is a more convergent one step procedure from 6 as compared to the current commercial process, with an improved yield from 59% (two steps) to 70%. Further improvements include eliminating the need for problematic magnesium tert-butoxide (MTB) and significant solvent reduction by eliminating the need for an intermediate workup. With the costs of HIV/AIDS tre…
La stereotomia nella cattedra di Architettura statica di Carlo Giachery
2014
La scuola di architettura di Palermo, sin dalla sua fondazione nel 1779, con la creazione della cattedra di Architettura civile affidata a Giuseppe Venanzio Marvuglia, era divenuta inevitabilmente il luogo di verifica e talvolta di esplorazione dei temi legati alla pratica professionale e, quindi, all’arte del costruire. Giachery, Professore di Architettura statica e civile dal 1837 al 1865, è il primo ad avvertire, da docente, la crisi profonda del sistema didattico della scuola di architettura di Palermo isterilita dalla ricerca di astratte idealità neoclassiche e straniatasi dal processo evolutivo della cultura architettonica europea dopo la morte dei “maestri” Marviglia e Gentile. Secon…
Barriers to insulin initiation and intensification and how to overcome them
2009
Summary Aims: To review published evidence and clinical experience of the perceived barriers to insulin initiation and intensification and to develop solutions for patient management. Method: Literature review and workshop discussions. Results: Many patients with diabetes fail to achieve targets for glycaemic control because of inappropriate use of insulin. Patients and health care professionals face many potential barriers to insulin initiation and intensification in primary care. These can be categorised as low motivation, lack of familiarity or experience and time constraints. Conclusion: Solutions should be tailored to different health care settings. Strategies include improving edu…
Re-emergence of HIV Infection and Syphilis Among Men Who Have Sex with Men
2012
Sexual activity has been shown to be the primary mode of transmission for several important viral and bacterial infections among men who have sex with men (MSM) throughout the world and therefore sexually transmitted infections (STIs) are still one of major public health problem worldwide. Since the earliest days of the human immunodeficiency virus (HIV) epidemic MSM have been profoundly affected by the disease; by the time the first AIDS cases were reported in the early 1980s, HIV had already spread widely among homosexual and drug-user communities. In western Europe, has been estimated that HIV incidence peaked around 1983 among MSM and in 1987-88 among injecting drug users, with 120.000 …
Self-efficacy in AIDS sexual prevention: influence of gender
2013
La literatura científica apunta a que la escasa autoeficacia para el uso del preservativo explicaría muchas conductas de riesgo de transmisión del VIH en jóvenes. Se analiza la autoeficacia de los jóvenes en el uso del preservativo, la existencia de diferencias de género y la relación con variables relevantes en la prevención. Se aplicó la "Subescala de Autoeficacia en el Uso del Preservativo", incluida en el Cuestionario de Prevención del Sida (Ballester, Gil y Giménez, 2007), a 3540 universitarios (50.9% mujeres, 49.1% hombres). Los resultados indican que los jóvenes obtienen puntuaciones medias-altas en autoeficacia, mostrándose la menor puntuación en el autocontrol en el momento de exci…
Autoeficacia en la prevención sexual del Sida: la influencia del género
2013
Title: Self-efficacy in AIDS sexual prevention: influence of gender. Abstract: The scientific literature suggests that a low self-efficacy for con- dom use may be related to many risky behaviors for HIV transmission in young people. We analyze the self-efficacy of condom use among youth, the existence of gender differences and the relationship with other relevant variables in HIV prevention. The "Self-Efficacy Condom Use Subscale", included in the AIDS Prevention Questionnaire (Ballester, Gil and Gimenez, 2007), was administrated to 3540 university students (50.9% women, 49.1% men). The results showed that the sample obtained medi- um-high scores on self-efficacy, showing the lowest scores …
Funcionamiento neuropsicológico en drogodependientes VIH/SIDA inmunodeprimidos: Importancia de la fase de la infección y del consumo de drogas
2000
Todavía no disponemos de factores de riesgo definitivos que permitan predecir la naturaleza y magnitud de las complicaciones neuropsicológicas asociadas a la infección por VIH. Con este trabajo nos planteamos estudiar la naturaleza del deterioro neuropsicológico asociado al VIH en drogodependientes con historia de consumo de drogas por vía intravenosa inmunodeprimidos, así como determinar la influencia que tienen sobre el mismo la fase clínica de la infección (asintomáticolSIDA) y el consumo de drogas. Para ello hemos utilizado una muestra de 20 drogodependientes voluntarios en distintas fases de la infección (A3 y C3). En cada uno de estos grupos la mitad de los sujetos se encuentra en abs…