Search results for "ALTER"

T-wave alternans analysis improvement by means of curve alignment prior to distance calculation.

2007

Tracking of repolarization instabilities in the ECG, such as T-wave alternans (TWA), has become a popular non-invasive method to assess the vulnerability to malignant arrhythmic events. These instabilities are usually characterized by small amplitude changes and their measurement is difficult due to the presence of noise and artifacts. Several methods have been recently proposed to address this problem. Most of them are based on amplitude analysis of beat-to-beat alternation of the T wave. This paper describes a preprocessing stage intended to be used prior to amplitude analysis and aimed at improving the alignment between consecutive T waves. This increases the accuracy of the difference c…

"And then they found her body" : T. S. Eliot's corporeal Cocktail party

2003

A Pedagogy of ht Subalterns: Gramsci and the Groups 'on the margins of history'

2017

In the 1980s, a group of South Asian scholars pioneered Subaltern Studies drawing on one of Gramsci’s most famous and used categories: the subaltern. This chapter attempts a philological analysis of Gramsci’s work to show how the use of this term has been at times incorrect, in part because of the lack, until recently, of complete translations of Gramsci’s writings. Subaltern Studies’ interpretation has arguably oriented Gramsci’s notion of the subaltern to the ethical and political needs of an emancipatory project. This does not completely undermine the fruitfulness of a scholarship capable of using a concept which had been previously neglected in defining marginal individuals without bind…

New Alkenylresorcinols with Cytotoxic and Antimicrobial Activities from the Leaves of Embelia schimperi.

2020

AbstractA phytochemical study of the methanol extract of the leaves of Embelia schimperi resulted in the isolation of three new alkenylresorcinols, 1 – 3, together with the known analogs 4 – 7. Their structures were established by a combination of spectroscopic techniques. Compounds 1 – 7 exhibited moderate cytotoxic activity against human cervical cancer cells HeLa-S3 and more pronounced antimicrobial properties towards bacteria and filamentous fungi. The present study falls into an ongoing research project on the characterization of bioactive phenolic lipids from plants of the family Primulaceae.

The RNA-binding protein ELAV regulates Hox RNA processing, expression and function within the Drosophila nervous system

2014

The regulated head-to-tail expression of Hox genes provides a coordinate system for the activation of specific programmes of cell differentiation according to axial level. Recent work indicates that Hox expression can be regulated via RNA processing but the underlying mechanisms and biological significance of this form of regulation remain poorly understood. Here we explore these issues within the developing Drosophila central nervous system (CNS). We show that the pan-neural RNA-binding protein (RBP) ELAV (Hu antigen) regulates the RNA processing patterns of the Hox gene Ultrabithorax (Ubx) within the embryonic CNS. Using a combination of biochemical, genetic and imaging approaches we demo…

High resolution computed tomography quantitation of emphysema is correlated with selected lung function values in stable COPD.

2011

BACKGROUND: The literature shows conflicting results when high-resolution computed tomography (HRCT) scores of emphysema were correlated with different indices of airflow obstruction. OBJECTIVES: We correlated HRCT scores of emphysema with different indices of airflow obstruction. METHODS: We performed HRCT of the chest in 59 patients, all smokers or ex-smokers, with stable chronic obstructive pulmonary disease of different severity [GOLD stages I-IV; mean age ± SD 67.8 ± 7.3 years; pack/years 51.0 ± 34.6; percent predicted forced expiratory volume in 1 s (FEV(1)% predicted) 52.3 ± 17.6; post-bronchodilator FEV(1)% predicted 56.5 ± 19.1; FEV(1)/forced vital capacity (FVC) ratio 50.8 ± 10.2;…

Striving to maintain a dignified life for the patient in transition: Next of kin’s experiences during the transition process of an older person in tr…

2015

Next of kin represent significant resources in the care for older patients. The aim of this study was to describe and illuminate the meaning of the next of kin’s experiences during the transition of an older person with continuing care needs from hospital to home. The study has a phenomenological hermeneutic design. Individual, narrative interviews were conducted, and the data analysis was conducted in accordance with Lindseth and Norberg’s phenomenological hermeneutic method. Two themes and four subthemes were identified and formulated. The first theme: “Balancing vulnerability and strength,” encompassed the subthemes “enduring emotional stress” and “striving to maintain security and conti…

Alteraciones del sueño producidas por el ruido ambiental*

1989

ResumenEste articulo presenta los resultados de una encuesta realizada con el objetivo de valorar distintos aspectos relacionados con el ruido ambiental y sus efectos sobre determinadas comunidades urbanas. Un total de 263 residentes en 5 emplazamientos diferentes de la ciudad de Valencia fueron entrevistados. En estos 5 emplazamientos se realizaron de manera independiente una serie de medidas de los niveles de ruido durante las 24 horas del dia y en distintos días de la semana.:El 400%0 de los encuestados manifestó tener alguna dificultad para dormirse y el 59% de ellos lo atribuyó al ruido causado por el tráfico. Asimismo, un 49% de los encuestados declaró despertarse durante la noche (el…

Modulation of Diabetes by Natural Products and Medicinal Plants via Incretins

2019

Incretins are metabolic hormones released after a meal that increase insulin secretion from pancreatic β-cells. The two main incretins are the intestinal peptides glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide. Both induce a decrease in glycemia, slow down the absorption of nutrients, and are inactivated by the enzyme dipeptidyl peptidase-4. Recently, incretin-based therapies have become a useful tool to treat diabetic patients, and different studies have focused on the identification of glucagon-like peptide-1 receptor agonists, including those of natural origin. This review focuses on the new findings of medicinal plants and natural products as possible active ag…

Hydrogen Production from Sea Wave for Alternative Energy Vehicles for Public Transport in Trapani (Italy)

2016

The coupling of renewable energy and hydrogen technologies represents in the mid-term a very interesting way to match the tasks of increasing the reliable exploitation of wind and sea wave energy and introducing clean technologies in the transportation sector. This paper presents two different feasibility studies: the first proposes two plants based on wind and sea wave resource for the production, storage and distribution of hydrogen for public transportation facilities in the West Sicily; the second applies the same approach to Pantelleria (a smaller island), including also some indications about solar resource. In both cases, all buses will be equipped with fuel-cells. A first economic a…