Search results for "ARFI"
showing 10 items of 103 documents
Could growth hormone play a role in Peutz Jeghers syndrome?
2013
Convincing experimental data suggest that the growth hormone (GH)/insulin-like growth factor-1(IGF-1) axis plays an important role in cancer development and behaviour. Epidemiological studies have supported an association with cancer, but not with tumour induction per se, although this is a distinction that is important mechanistically but not clinically [1]. We report the case of a 17-year-old man with delayed growth of pituitary origin, treated with growth hormone, in whom a diagnosis of Peutz-Jeghers syndrome (PJS) was subsequently made, and in whom, during the endoscopic follow-up, the number of polyps reduced dramatically, thus suggesting a role for GH in eliciting this disease.
Les enfants difficiles à table : conceptualisation et évolution
2022
L'objectif du présent article est de proposer un état des lieux des études récentes permettant d'offrir un cadre conceptuel et opérationnel au concept de comportement difficile à table, tout en mettant en lumière les conséquences psychologiques pour l'enfant, ainsi que les pratiques éducatives parentales associées. L'article ambitionne aussi de déterminer dans quelle mesure un enfant difficile est un mangeur à risque de développer ultérieurement des troubles du comportement alimentaire (anorexie mentale, ARFID), et quelles seraient les pistes à privilégier, en termes de guidance parentale, pour accompagner l'enfant.
LOW VIGOR PEACH × ALMOND ROOTSTOCKS FOR INTENSIVE PEACH PLANTINGS IN MEDITERRANEAN ENVIRONMENTS
2014
A three-year trial was carried out to evaluate the vegetative and productive performance of five peach rootstocks of varied vigor. The study was conducted in south-western Sicily using 45 V-trained trees of 'Tropic Snow' peach planted in 2005 and grafted on GF677 and four low-vigor rootstocks selected at the Department of Agricultural, Food and Environmental Sciences, University of Pisa, namely IS5/8 (Polluce), IS5/19 (Castore), IS5/23, IS5/29. Trunk circumference, winter and summer pruning weight, number and mass of fruit were recorded from 2010 to 2012. All IS selections reduced trunk cross-sectional area (TCSA) and pruning weight compared to GF677 with IS5/23 inducing the highest reducti…
The operational sex ratio of the sea urchin Paracentrotus lividus populations: the case of the Mediterranean marine protected area of Ustica Island (…
2009
We investigated, with a series of field and laboratory observations, the possible effect of the starfish Marthasteria glacialis predation on the operational sex ratio (OSR), i.e. the number of sexually mature males divided by the total number of sexually mature adults of both sexes at any one time, of the edible sea urchin Paracentrotus lividus. The OSR was estimated three times during the sea urchin summer spawning period (July 2004, June 2005 and July 2006) on barren substrates of Ustica Island Marine Protected Area (Southern Tyrrhenian Sea, Italy). Four sites were selected: two characterized by high M. glacialis density (take zone C) and two controls with low starfish density (no-take zo…
Defining the Island Dwarfing Rate of an Extinct Sicilian Elephant Using Ancient DNA
2020
Evolution on islands, and the often extreme phenotypic changes associated with it, has attracted much interest from evolutionary biologists. However, measuring the rate of change of a particular phenotypic trait of extinct animals can be challenging, due to the incompleteness of the fossil record. Here, we use combined molecular and fossil evidence to define the minimum and maximum rate of dwarfing in an extinct Mediterranean dwarf elephant from Puntali Cave (Sicily). Despite the challenges associated with recovering ancient DNA from warm climates, we successfully retrieved a mitogenome from a sample with an estimated age between 147,000 and 50,000 years. Our results suggest that this speci…
Pusaudžu izvairīgas/ierobežojošas pārtikas uzņemšanas traucējuma iezīmju, sensorā jutīguma un internalizētu uzvedības problēmu sakarības
2022
Darba mērķis ir izpētīt ARFID iezīmju, sensorā jutīguma un internalizēto uzvedības problēmu sakarības pusaudžiem. Pētījumā piedalījās 271 pusaudzis 14 – 18 gadu vecumā. Pētījumā tika izmantotas trīs aptaujas – Deviņu jautājumu ARFID aptauja, Īpaši jutīga bērna aptauja, Ahenbaha jaunieša uzvedības pašnovērtēšanas aptaujas internalizēto uzvedības problēmu skalas. Rezultāti parādīja, ka pastāv statistiski nozīmīgas pozitīvas saistības starp pusaudžu ARFID iezīmēm, sensoro jutīgumu un internalizētām uzvedības problēmām. Meitenēm tika novērotas izteiktākas ARFID iezīmes, sensorais jutīgums un internalizētas uzvedības problēmas nekā zēniem. Internalizētas uzvedības problēmu kopējie rādītāji progn…
Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of Atrip-Seckel syndrome
2020
ABSTRACT Seckel syndrome is a type of microcephalic primordial dwarfism (MPD) that is characterized by growth retardation and neurodevelopmental defects, including reports of retinopathy. Mutations in key mediators of the replication stress response, the mutually dependent partners ATR and ATRIP, are among the known causes of Seckel syndrome. However, it remains unclear how their deficiency disrupts the development and function of the central nervous system (CNS). Here, we investigated the cellular and molecular consequences of ATRIP deficiency in different cell populations of the developing murine neural retina. We discovered that conditional inactivation of Atrip in photoreceptor neurons …
Peines de marfil y madera de la II Edad del Hierro en la Peninsula Ibérica. Talleres, estilos y otros enredos
2017
Desde la Prehistoria, diversos objetos han sido elaborados en materias duras de origen animal (hueso, asta, marfil, cuerno, concha), destacando entre aquellas el marfil por ser un material exótico. En este trabajo se analiza un conjunto de peines de marfil y madera procedentes de yacimientos de la II Edad del Hierro de la Península Ibérica. Su estudio ha permitido ofrecer una visión renovada sobre estos objetos, cuyos patrones formales y ornamentales evidencian su fabricación autóctona en unos pocos lugares desde donde se difunden a áreas distantes. Además, las evidencias que aportan los contextos y las cronologías trazan nuevos códigos de lectura para hacer una aproximación sobre los artes…
Bright spots in the darkness of cancer: A review of starfishes-derived compounds and their anti-tumor action
2019
The fight against cancer represents a great challenge for researchers and, for this reason, the search for new promising drugs to improve cancer treatments has become inevitable. Oceans, due to their wide diversity of marine species and environmental conditions have proven to be precious sources of potential natural drugs with active properties. As an example, in this context several studies performed on sponges, tunicates, mollusks, and soft corals have brought evidence of the interesting biological activities of the molecules derived from these species. Also, echinoderms constitute an important phylum, whose members produce a huge number of compounds with diverse biological activities. In…
Autosomal recessive severe dwarfism in a Sicilian girl: a new form of osteodysplastic primordial dwarfism?
1996
A new type of osteodysplastic primordial dwarfism is delineated in a 5- year-old female child with severe growth retardation of prenatal onset, gross skeletal changes, a non-Seckel facial phenotype, and presumed autosomal recessive inheritance.