Search results for "ASIC"

showing 10 items of 11113 documents

Analysis of heteroplasmy in bank voles inhabiting the Chernobyl exclusion zone : A commentary on Baker et al. (2017) "Elevated mitochondrial genome v…

2018

0106 biological sciences0301 basic medicineMitochondrial DNARodentmetsämyyräecological geneticsevoluutio010603 evolutionary biology01 natural sciences03 medical and health sciencesMolecular evolutionbiology.animalGeneticsExclusion zoneEcology Evolution Behavior and Systematicsbiologymolecular evolutionsäteilyPopulation ecologyEcological geneticsgeneettinen muunteluHeteroplasmypopulaatioekologia030104 developmental biologyVariation (linguistics)Evolutionary biologypopulation ecologyCommentaryta1181mutaatiotGeneral Agricultural and Biological SciencesEvolutionary Applications
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Mitochondrial heteroplasmy in an avian hybrid form (Passer italiae: Aves, Passeriformes)

2019

Mitochondrial heteroplasmy is the result from biparental transmission of mitochondrial DNA (mtDNA) to the offspring. In such rare cases, maternal and paternal mtDNA is present in the same individual. Though recent studies suggested that mtDNA heteroplasmy might be more common than previously anticipated, that phenomenon is still poorly documented and was mostly detected in case studies on hybrid populations. The Italian sparrow, Passer italiae is a homoploid hybrid form that occurs all across the Italian Peninsula mostly under strict absence of either of its parent species, the house sparrow (P. domesticus) and the Spanish sparrow (P. hispaniolensis). In this study, we document a new case o…

0106 biological sciences0301 basic medicineMitochondrial DNASettore BIO/05 - ZoologiaMediterranean010603 evolutionary biology01 natural sciences03 medical and health sciencesbiology.animalGeneticsItalian sparrowMolecular BiologyhybridizationSpanish sparrowSparrowbiologysparrowsHaplotypeNADH dehydrogenasebiology.organism_classificationHeteroplasmy030104 developmental biologyEvolutionary biologyPaternal leakagebiology.proteinPasser
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Multilocus and morphological analysis of south‐eastern Iberian Wall lizards (Squamata,Podarcis)

2020

The phylogenetic relationships among the wall lizards of the Podarcis hispanicus complex that inhabit the south-east (SE) of the Iberian Peninsula and other lineages of the complex remain unclear. In this study, four mitochondrial and two nuclear markers were used to study genetic relationships within this complex. The phylogenetic analyses based on mtDNA gene trees constructed with ML and BI, and a species tree using *BEAST support three divergent clades in this region: the Valencia, Galera and Albacete/Murcia lineages. These three lineages were also corroborated in species delimitation analyses based on mtDNA using bPTP, mPTP, GMYC, ABGD and BAPS. Bayesian inference species delimitation m…

0106 biological sciences0301 basic medicineMitochondrial DNASquamataPhylogenetic treebiologyLineage (evolution)Podarcisbiology.organism_classification010603 evolutionary biology01 natural sciences03 medical and health sciences030104 developmental biologyPodarcis vaucheriEvolutionary biologyPhylogeneticsGeneticsAnimal Science and ZoologyCladeMolecular BiologyEcology Evolution Behavior and SystematicsZoologica Scripta
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Stress integrated tests and cytological analyses reveal Brassica villosa subsp. drepanensis seed quality decrease upon long-term storage

2016

Under stress integrated germination test (SIGT), seeds undergo osmo-saline stresses, which enable to detect differences in vigour of long-term stored seeds with high germination percentage (G%). The quality of Brassica villosa subsp. drepanensis seeds stored in a genebank (at -20°C for 16 years) was compared with seeds at harvest by standard germination tests (GT), SIGT and cytogenetic analysis. No differences were detected in G% and mean germination time under GT. Conversely, SIGT performed with NaCl -0.9MPa osmotic potential did not influence G% at harvest but reduced that of stored seeds, SIGT at -1.4MPa reduced G% of both. Cytogenetic analysis showed reduction of mitotic index, appearan…

0106 biological sciences0301 basic medicineMitotic indexPlant ScienceBiologygenebankBrassica villosa subsp. drepanensis genebank genotoxicity germination seed storage stress integrated germination test01 natural sciencesBrassica villosa subsp. drepanensis; genebank; genotoxicity; germination; seed storage; stress integrated germination testSettore BIO/01 - Botanica Generale03 medical and health sciencesBrassica villosa subsp. drepanensisOsmotic pressureEcology Evolution Behavior and SystematicsBrassica villosa subsp. drepanensisstress integrated germination testgenotoxicityfood and beveragesseed storageHorticultureBrassica villosa030104 developmental biologyAgronomygerminationGermination010606 plant biology & botany
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Phosphinotripeptidic Inhibitors of Leucylaminopeptidases

2021

Phosphinate pseudopeptide are analogs of peptides containing phosphinate moiety in a place of the amide bond. Due to this, the organophosphorus fragment resembles the tetrahedral transition state of the amide bond hydrolysis. Additionally, it is also capable of coordinating metal ions, for example, zinc or magnesium ions. These two properties of phosphinate pseudopeptides make them an ideal candidate for metal-related protease inhibitors. This research investigates the influence of additional residue in the P2 position on the inhibitory properties of phosphinopeptides. The synthetic strategy is proposed, based on retrosynthetic analysis. The N-C-P bond formation in the desired compounds is …

0106 biological sciences0301 basic medicineModels MolecularMolecular modelQH301-705.5StereochemistryPhosphinesProtein ConformationSwineLAP inhibitorsligand-enzyme interactionPhosphinate01 natural sciencesAminopeptidaseCatalysisArticleInorganic Chemistry03 medical and health sciencesResidue (chemistry)phosphinate pseudopeptideLeucyl AminopeptidaseMoietyPeptide bondAnimalsBiology (General)Physical and Theoretical ChemistryEnzyme InhibitorsQD1-999Molecular BiologyMagnesium ionmolecular modeling; LAP inhibitors; barley aminopeptidase inhibitor; phosphinate pseudopeptide; ligand-enzyme interaction; organophosphorus compoundSpectroscopyChemistrymolecular modelingOrganic ChemistryGeneral Medicineorganophosphorus compoundPeptide FragmentsComputer Science ApplicationsChemistry030104 developmental biologybarley aminopeptidase inhibitorHordeum vulgare010606 plant biology & botanyInternational Journal of Molecular Sciences; Volume 22; Issue 10; Pages: 5090
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The Odorant-Binding Proteins of the Spider Mite Tetranychus urticae

2021

Spider mites are one of the major agricultural pests, feeding on a large variety of plants. As a contribution to understanding chemical communication in these arthropods, we have characterized a recently discovered class of odorant-binding proteins (OBPs) in Tetranychus urticae. As in other species of Chelicerata, the four OBPs of T. urticae contain six conserved cysteines paired in a pattern (C1–C6, C2–C3, C4–C5) differing from that of insect counterparts (C1–C3, C2–C5, C4–C6). Proteomic analysis uncovered a second family of OBPs, including twelve members that are likely to be unique to T. urticae. A three-dimensional model of TurtOBP1, built on the recent X-ray structure of Varroa destruc…

0106 biological sciences0301 basic medicineModels MolecularProteomicsProteomeOdorant bindingProtein ConformationInsectLigandsReceptors Odorant01 natural scienceschemistry.chemical_compoundTetranychus urticaeBiology (General)SpectroscopyPhylogenymedia_commonmass spectrometryGeneticsbiologyligand-bindingMolecular Structurespider mitesGeneral MedicineTetranychus urticaeComputer Science ApplicationsChemistryConiferyl aldehydedisulfide bridgesTetranychidaeProtein Bindingspider mites.QH301-705.5media_common.quotation_subjectodorant-binding proteinsCatalysisArticleInorganic Chemistry03 medical and health sciencesSpider mite<i>Tetranychus urticae</i>AnimalsAmino Acid SequencePhysical and Theoretical ChemistryQD1-999Molecular BiologySpiderOrganic Chemistrybiology.organism_classification010602 entomology030104 developmental biologychemistryVarroa destructorOdorantsChelicerataInternational Journal of Molecular Sciences
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Root growth compensates for molar wear in adult goats (Capra aegagrus hircus)

2018

One reason for the mammalian clade’s success is the evolutionary diversity of their teeth. In herbivores, this is represented by high‐crowned teeth evolved to compensate for wear caused by dietary abrasives like phytoliths and grit. Exactly how dietary abrasives wear teeth is still not understood completely. We fed four different pelleted diets of increasing abrasiveness (L: Lucerne; G: grass; GR: grass and rice husks; GRS: grass, rice husks, and sand) to four groups of a total of 28 adult goats, all with completely erupted third molars, over a six‐month period. Tooth morphology was captured by medical computed tomography scans at the beginning and end of the controlled feeding experiment, …

0106 biological sciences0301 basic medicineMolarRoot growthPhysiologyCapra aegagrusBiology010603 evolutionary biology01 natural sciencesMandibular second molar03 medical and health sciencesAnimal sciencestomatognathic systemGeneticsmedicineCementumRoot volumeMolecular BiologyEcology Evolution Behavior and Systematics2. Zero hungerHerbivorestomatognathic diseases030104 developmental biologymedicine.anatomical_structureVolume (thermodynamics)Animal Science and ZoologyJournal of Experimental Zoology Part A: Ecological and Integrative Physiology
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Genetic Component of Morphological Differentiation in Coal Tits Under Competitive Release

1987

0106 biological sciences0301 basic medicineMorphological differentiationbusiness.industryPopulation geneticsBiology010603 evolutionary biology01 natural sciences03 medical and health sciences030104 developmental biologyEvolutionary biologyComponent (UML)GeneticsCoalGene–environment interactionbusinessGeneral Agricultural and Biological SciencesEcology Evolution Behavior and SystematicsEvolution
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2016

Cold acclimation is a critical physiological adaptation for coping with seasonal cold. By increasing their cold tolerance individuals can remain active for longer at the onset of winter and can recover more quickly from a cold shock. In insects, despite many physiological studies, little is known about the genetic basis of cold acclimation. Recently, transcriptomic analyses in Drosophila virilis and D. montana revealed candidate genes for cold acclimation by identifying genes upregulated during exposure to cold. Here, we test the role of myo-inositol-1-phosphate synthase (Inos), in cold tolerance in D. montana using an RNAi approach. D. montana has a circumpolar distribution and overwinters…

0106 biological sciences0301 basic medicineMultidisciplinaryfungiInsect physiologyBiologybiology.organism_classification010603 evolutionary biology01 natural sciencesAcclimatizationCell biologyDrosophila virilis03 medical and health sciences030104 developmental biologyBotanyCold acclimationmedicineCold sensitivityDrosophila melanogastermedicine.symptomExtreme ColdOverwinteringPLOS ONE
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Genomic processes underlying rapid adaptation of a natural Chironomus riparius population to unintendedly applied experimental selection pressures

2020

Evolve and Resquence (E&R) studies are a useful tool to study genomic processes during rapid adaptation, e.g., in the framework of adaptive responses to global climate change. We applied different thermal regimes to a natural Chironomus riparius (Diptera) population in an E&R framework to infer its evolutionary potential for rapid thermal adaptation. We exposed two replicates to three temperatures each (14°C, 20°C and 26°C) for more than two years, the experiment thus lasting 22, 44 or 65 generations, respectively. The two higher temperatures presented a priori moderate, respectively strong selection pressures. Life-cycle fitness tests revealed no appreciable adaptation to thermal regimes b…

0106 biological sciences0301 basic medicineMultifactorial InheritanceClimate ChangePopulationved/biology.organism_classification_rank.speciesSingle-nucleotide polymorphismBiologyPolymorphism Single Nucleotide010603 evolutionary biology01 natural sciencesChironomidae03 medical and health sciencesGene FrequencyGenetic variationGeneticsAnimalsSelection GeneticeducationGeneAllele frequencyEcology Evolution Behavior and SystematicsChironomus ripariusLife Cycle Stageseducation.field_of_studyved/biologySelection coefficientTemperatureGenomicsAdaptation PhysiologicalBiological EvolutionGenetics Population030104 developmental biologyEvolutionary biologyMolecular Ecology
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