Search results for "ASIS"

showing 10 items of 4190 documents

Operāciju māsu darba izvērtējums torakotomijas un video asistētas torakoskopijas operāciju laikā

2020

Bakalaura darbs „Operāciju māsu darba izvērtējums torakotomijas un video asistētas torakoskopijas operāciju laikā” izstrādāts ar mērķi izvērtēt operāciju māsu darbu torakotomijas un vidoeasistētas torakoskopijas operāciju laikā. Mērķa sasniegšanai tika izvēlēta kvalitatīvā pētniecības metode. Izvirzīts pētījuma jautājums- kāds ir operāciju māsu darbs videoasistētas torakoskopijas un torakotomijas operāciju laikā? Bakalaura darba tēmas izvēle balstās uz darba autores pieredzi strādājot torakālās operācijas nodaļā. Operāciju māsas darbs norit pie dažādu profilu operācijām. Katra no operācijām ir ar savu darba specifiku, kas māsai labi jāpārzina. Darba process pie torakālajām operācijām ir spe…

operāciju māsas darbstorakotomijatorakālā ķirurģijavideo asistēta torakoskopijaMedicīna
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Documentació mèdica: Comunicació (Grau Medicina)

2014

El document forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València. Una assistència de qualitat requereix necessàriament professionals de la salut amb sòlids coneixements sobre els elements necessaris per al registre i recuperació de la informació clínica i l'obtenció d'informació sanitària. La finalitat de l'Àrea de Documentació com a part de l'assignatura de Comunicació pot resumir-se en aquests tres punts: - Adquirir coneixements sobre els processos de comunicació entre els professionals dins de l'acompliment de la seua activitat assistencial. - Conèixer l'organització sanitària per a comprendre les necessitats d'in…

organización sanitariaterminología médicaUNESCO::CIENCIAS MÉDICASdocumentación médicainformación sanitaria y asistencial
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Characterization of strong chain geometries by their automorphism group

1992

A wide class of chain geometries is characterized by their automorphism group using properties of a distinguished involution.

p-groupDiscrete mathematicsMathematics::Group TheoryPure mathematicsInner automorphismQuasisimple groupQuaternion groupSO(8)Outer automorphism groupAlternating groupGeometry and TopologyAutomorphismMathematicsGeometriae Dedicata
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Increased dosage of Ink4/Arf protects against glucose intolerance and insulin resistance associated with aging

2013

Recent genome-wide association studies have linked type-2 diabetes mellitus to a genomic region in chromosome 9p21 near the Ink4/Arf locus, which encodes tumor suppressors that are up-regulated in a variety of mammalian organs during aging. However, it is unclear whether the susceptibility to type-2 diabetes is associated with altered expression of the Ink4/Arf locus. In the present study, we investigated the role of Ink4/Arf in age-dependent alterations of insulin and glucose homeostasis using Super-Ink4/Arf mice which bear an extra copy of the entire Ink4/Arf locus. We find that, in contrast to age-matched wild-type controls, Super-Ink4/Arf mice do not develop glucose intolerance with agi…

p16ink4amedicine.medical_specialtyAgingGlucose uptakemedicine.medical_treatmentMice TransgenicCarbohydrate metabolismCDKN2BMiceCDKN2AInsulin resistanceInsulin receptor substrateInternal medicineDiabetes mellitusinsulin resistanceGlucose IntolerancemedicineGlucose homeostasisAnimalsInsulininsulin signalingCyclin-Dependent Kinase Inhibitor p16biologydiabetesADP-Ribosylation FactorsInsulin18F-fluorodeoxyglucose-PETARFCell Biologypancreatic isletmedicine.diseaseMice Inbred C57BLInsulin receptorEndocrinologyGlucosebiology.proteinInsulin Resistancep15ink4bGenome-Wide Association Study
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Genetic profile and immunohistochemical study of clear cell renal carcinoma: Pathological-anatomical correlation and prognosis.

2021

Abstract Introduction Renal cell carcinoma (RCC) accounts for 2–3% of all tumors being the most frequent solid lesion in the kidney. Objective To determine what genetic alterations and immunohistochemical (IHC) of clear cell renal carcinoma (ccRCC) are associated with prognosis and tumor aggressiveness. Patients and Methods Experimental analytical study with 57 patients who underwent radical and partial nephrectomy between 2005 and 2011, all with diagnosis of ccRCC and minimum post-operative follow-up of 36 months. The pathological study included IHC determination of biomarkers associated (CAIX, CAM 5.2, CD10, c-erbB-2, EGFR, HIF-1a, Ki67, MDM2, PAX-2 y 8, p53, survivin and VEGFR 1 and 2). …

p530301 basic medicineMaleCancer Researchmedicine.medical_treatmentGastroenterologyNephrectomy0302 clinical medicineFHITRenal cell carcinomaCDKN2ANeoplasm MetastasisClear cell renal carcinomaRC254-282KidneyBRCA1 y 2Neoplasms. Tumors. Oncology. Including cancer and carcinogensCDKN2A: cyclin-dependent kinase Inhibitor 2AMiddle AgedPrognosisImmunohistochemistryNephrectomyKidney NeoplasmsMLPATumor BurdenSurvival Ratemedicine.anatomical_structureOncology030220 oncology & carcinogenesisImmunohistochemistryFemalemedicine.medical_specialty03 medical and health sciencesInternal medicinemedicineHumansMultiplex ligation-dependent probe amplificationCarbonic Anhydrase IXSurvival rateCarcinoma Renal CellAgedNeoplasm Stagingbusiness.industryCAIXmedicine.disease030104 developmental biologyNeoplasm GradingNeoplasm Recurrence LocalbusinessTranscriptomeFollow-Up StudiesCancer treatment and research communications
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Heterogeneity within and between primary colorectal carcinomas and matched metastases as revealed by analysis of Ki-ras and p53 mutations

2004

Analysis of the genetic status of Ki-ras and p53 in primary colorectal carcinomas and matched colorectal liver metastasis from 30 patients reveals an overall heterogeneity both within and between the two tumoral tissues. Both genes were found mutated with a similar frequency in both tissues; however, identical mutations in primary tumor and matched metastasis were found less frequently in the case of the Ki-ras than the p53 gene. Only in three cases the same p53 and Ki-ras mutations found in the primary tumor were found also in the metastasis. In several metastatic specimens the DNA bearing a mutation detected also in the primary tumor appears significantly less abundant than the wild-type …

p53Colorectal cancerDNA Mutational AnalysisStatistics as TopicBiophysicsKi-raBiologyOncogene Protein p21(ras)medicine.disease_causeBiochemistryMetastasisMetastasischemistry.chemical_compoundSequence Homology Nucleic AcidmedicineHumansMolecular BiologyGeneRegulation of gene expressionMutationGene Expression ProfilingCarcinomaLiver NeoplasmsCell BiologySequence Analysis DNAmedicine.diseasePrimary tumorGene expression profilingGene Expression Regulation NeoplasticColorectal carcinomaGenes raschemistryMutationCancer researchTumor Suppressor Protein p53Colorectal NeoplasmsDNA
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Zāļu pieejamība

2019

Maģistra darba tēma ir „Zāļu pieejamība”. Neskatoties uz plašu medikamentu piedāvājumu Latvijā, joprojām ir aktuālszāļu piejamības jautājums. Maģistra darba mērķis ir noskaidrotfarmācijas speciālistu un pacientu viedokļus par zāļu pieejamību aptiekās. Informācija ir iegūta no datu bāzēm, publikācijām, normatīvajiem aktiem, statistikas datiem, aptaujām. Darbs veikts LU Medicīnas fakultātē Farmācijas maģistra programmā.

pacientifarmaceitiFarmācijazāļu pieejamībafarmaceita asistenti
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The Palliative Care in the Metastatic Spinal Tumors. A Systematic Review on the Radiotherapy and Surgical Perspective

2022

Spine represents the most common site for metastatic disease involvement. Due to the close relationship between the spinal cord and critical structures, therapeutic management of spinal metastases remains challenging. Spinal localization can lead to neurological sequelae, which can significantly affect the quality of life in patients with a limited life expectancy. The authors conducted a systematic literature review according to PRISMA guidelines in order to determine the impact of the most updated palliative care on spinal metastases. The initial literature search retrieved 2526 articles, manually screened based on detailed exclusion criteria. Finally, 65 studies met the inclusion criteri…

palliative carequality of lifespinal metastasisSpace and Planetary Sciencespinal cord stimulationSettore MED/27 - NeurochirurgiaPaleontologyradiofrequency ablationGeneral Biochemistry Genetics and Molecular BiologyEcology Evolution Behavior and Systematicsradiotherapyvertebral augmentation
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Experimental evolution of an RNA virus in cells with innate immunity defects

2015

Experimental evolution studies have shown that RNA viruses respond rapidly to directional selection and thus can adapt efficiently to changes in host cell tropism, antiviral drugs, or other imposed selective pressures. However, the evolution of RNA viruses under relaxed selection has been less extensively explored. Here, we evolved vesicular stomatitis virus in mouse embryonic fibroblasts knocked-out for PKR, a protein with a central role in antiviral innate immunity. Vesicular stomatitis virus adapted to PKR-negative mouse embryonic fibroblasts in a gene-specific manner, since the evolved viruses exhibited little or no fitness improvement in PKR-positive cells. Full-length sequencing revea…

parallel evolutionepistasisvirusesMutagenesis (molecular biology technique)Microbiology03 medical and health sciencesVirologyexperimental evolutionTropismattenuation030304 developmental biologyGenetics0303 health sciencesExperimental evolutionInnate immune systembiology030306 microbiology030302 biochemistry & molecular biologyRNARNA virusPKRbiology.organism_classificationVesicular stomatitis virusViral evolutionvesicular stomatitis virusCorrigendumResearch ArticleVirus Evolution
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A parasitoloxia e a doutrina do contáxio animado: a helmintiase e a sarna na España do século XIX

1990

Les explicacions parasitològiques del contagi eren tant teòriques com observacionals. La triquinosi, la sarna i la helmintiasi van ser exemples primerencs que van demostrar un contagi viu. A principis del segle XIX, en la medicina espanyola, igual que en la medicina europea, es rebutjava el contagi animat excepte en el cas d'alguns paràsits animals com la sarna. En uns altres, com en la helmintiasi intestinal, s'acceptava el seu origen viu, però no la seua contagiositat, i es defensava la seua generació espontània fins a ben entrat el segle XIX. En el “Diccionari de Ciències Mèdiques”, l'estudi dels cucs és quasi exclusivament morfològic i es defensa com a causa de la seua presència en l'ho…

parasitology19th centuryparasitologiahistory of microbiologyhistòria de la microbiologiahelminthiasisiglo XIXmange:CIENCIAS MÉDICAS ::Patología::Parasitología [UNESCO]UNESCO::HISTORIA::Historia por especialidades::Historia de la medicinaparasitologíasegle XIXhelmintiasi:HISTORIA::Historia por especialidades::Historia de la medicina [UNESCO]helmintiasisUNESCO::CIENCIAS MÉDICAS ::Patología::ParasitologíaUNESCO::CIENCIAS MÉDICAS ::Medicina interna::Enfermedades infecciosas:CIENCIAS MÉDICAS ::Medicina interna::Enfermedades infecciosas [UNESCO]sarnahistoria de la microbiología
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