Search results for "ATAL"

The proceedings of Spanish Audiovisual Councils on discriminatory discourse

2021

Mass media, and especially television, are powerful discursive instruments, responsible for the construction of social imagery through ideologically determined content. For this reason, the creation of a regulatory body with authority over the audiovisual sector in countries without one was urged by the Committee of Ministers of the Council of Europe in 2000. Spain is the only EU country without an audiovisual council with authority at the state level. Currently, only the Audiovisual Council of Catalonia (CAC), created in 2000, and the Audiovisual Council of Andalusia (CAA), which dates from 2004, operate in Spain. Within an environment increasingly marked by hate speech, this research anal…

La multisecular invocació de sant Vicent Ferrer com a defensor de la 'llengua valenciana'

2019

catalaAl llarg de la historia de la llengua catalana, el nom de sant Vicent Ferrer (ca. 1350- 1419) ha estat associat a l’estima per la seua llengua materna, ja que sempre va predicar «in sua vulgari idiomate Catalonie seu Valentino». Els valencians han utilitzat aquesta creenca per a invocar la proteccio de sant Vicent sobre la «llengua valenciana» y sobre el poble valencia. Es una de les raons que expliquen la gran popularitat del sant entre els valencians. Les modalitats amb que s’han expressat des del segle xvi les apologies de la llengua invocant l’exemple de sant Vicent posen de manifest una situacio de conflicte linguistic. EnglishThroughout the history of the Catalan language, the n…

Do key audit matters (KAMs) matter? : Auditors’ perceptions of KAMs and audit quality in Finland

2021

Purpose Key audit matters (KAMs) in International Standard for Auditing, 701 seek to enhance the value of the auditor’s report by increasing the transparency of how the audit was performed. The purpose of this study is to investigate how professional auditors themselves perceive the impact of KAMs on audit quality and audit effectiveness. Design/methodology/approach Statistical analyses of an electronic survey of certified public auditors (CPAs) in Finland. Findings Regarding the perceptions of KAMs, the authors found two dominant views on auditing: quality and efficiency. In general, the respondents did not consider that KAMs improve audit quality. However, auditors focusing on efficiency…

Postnatal neurogenesis and regeneration in the lizard cerebral cortex

1993

Determination of platinum and iridium in reforming catalysts by second derivative and absorptiometric spectrophotometry

1991

Investigations on the spectrophotometric determination of platinum as a complex formed by tin(II)chloride in hydrochloric acid are reported. The determination of platinum was found to be interfered with by iridium, because it also forms a complex with tin(II) chloride. The features of the derivative absorption spectrophotometry for the quantitative determination of platinum and iridium was also studied. The analytical application of the method for the determination of platinum and iridium in catalysts was investigated.

2019

(1) Background: The high-grade neuroepithelial tumor of the central nervous system with BCOR alteration (HGNET-BCOR) is a highly malignant tumor. Preclinical models and molecular targets are urgently required for this cancer. Previous data suggest a potential role of insulin-like growth factor (IGF) signaling in HGNET-BCOR. (2) Methods: The primary HGNET-BCOR cells PhKh1 were characterized by western blot, copy number variation, and methylation analysis and by electron microscopy. The expression of IGF2 and IGF1R was assessed by qRT-PCR. The effect of chemotherapeutics and IGF1R inhibitors on PhKh1 proliferation was tested. The phosphorylation of IGF1R and downstream molecules was assessed …

Self-adjuvanting synthetic antitumor vaccines from MUC1 glycopeptides conjugated to T-cell epitopes from tetanus toxoid.

2013

The T-helper epitope peptide P30 (green in the scheme) from tetanus toxoid was used as the immunostimulant in MUC1 glycopeptide antitumor vaccines and apparently also acts as a built-in adjuvant. P30-conjugated glycopeptide vaccines containing three glycans in the immunodominant motifs PDTRP and GSTAP induced much stronger immune responses and complement dependent cytotoxicity mediated killing of tumor cells when applied in plain PBS solution without complete Freund's adjuvant.

A Synthetic Glycopeptide Vaccine for the Induction of a Monoclonal Antibody that Differentiates between Normal and Tumor Mammary Cells and Enables th…

2015

In studies within the realm of cancer immunotherapy, the synthesis of exactly specified tumor-associated glycopeptide antigens is shown to be a key strategy for obtaining a highly selective biological reagent, that is, a monoclonal antibody that completely differentiates between tumor and normal epithelial cells and specifically marks the tumor cells in pancreas tumors. Mucin MUC1, which is overexpressed in many prevalent cancers, was identified as a promising target for this strategy. Tumor-associated MUC1 differs significantly from that expressed by normal cells, in particular by altered glycosylation. Structurally defined tumor-associated MUC1 cannot be isolated from tumor cells. We synt…

In utero exposure to mixtures of xenoestrogens and child neuropsychological development.

2014

BACKGROUND: To date, no epidemiological studies have explored the impact and persistence of in utero exposure to mixtures of xenoestrogens on the developing brain. We aimed to assess whether the cumulative effect of xenoestrogens in the placenta is associated with altered infant neuropsychological functioning at two and at four years of age, and if associations differ among boys and girls. METHODS: Cumulative prenatal exposure to xenoestrogens was quantified in the placenta using the biomarker Total Effective Xenoestrogen Burden (TEXB-alpha) in 489 participants from the INMA (Childhood and the Environment) Project. TEXB-alpha was split in tertiles to test its association with the mental and…

Multigenerational study of the obesogen effects of bisphenol S after a perinatal exposure in C57BL6/J mice fed a high fat diet.

2021

International audience; Background : Bisphenol S is an endocrine disruptor exhibiting metabolic disturbances, especially following perinatal exposures. To date, no data are available on the obesogen effects of BPS in a mutligenerational issue.Objectives : We investigated obesogen effects of BPS in a multigenerational study by focusing on body weight, adipose tissue and plasma parameters in male and female mice.Methods : Pregnant C57BL6/J mice were exposed to BPS (1.5 μg/kg bw/day ie a human equivalent dose of 0.12 μg/kg bw/day) by drinking water from gestational day 0 to post natal day 21. All offsprings were fed with a high fat diet during 15 weeks. Body weight was monitored weekly and fat…