Search results for "Abp"
showing 10 items of 43 documents
Prácticas de laboratorio alineadas con el diseño de un proyecto de investigación mediante metodología docente ABP: el proyecto Agua de Fagos
2016
[ES] Las prácticas de laboratorio académicas no están, en general, diseñadas para desarrollar las competencias relacionadas con el trabajo independiente del alumno. En el presente artículo proponemos una nueva forma de diseñar prácticas experimentales, alineando el desarrollo de un proyecto de investigación escrito con la realización posterior del proyecto a nivel práctico en el laboratorio, en un poderoso ensamble que genera aprendizajes muy interesantes para desarrollar las competencias relacionadas con la autonomía del alumno en el laboratorio experimental. La metodología utilizada es el aprendizaje basado en problema (ABP).
Projekts: Skaistumkopšanas salona "SK Elegance" dibināšana
2018
Darba mērķis: Jaunas sabiedrības ar ierobežotu atbildību dibināšana, kas darbojas skaistumkopšanas pakalpojumu nozarē. Maģistra darbs sastāv no septiņām nodaļām. Katra nodaļa ietver sevī svarīgu informāciju par jaunā uzņēmuma dibināšanas iespējamību un nepieciešamību. Maģistra darbs izstrādāts pamatojoties uz speciālo literatūru, interneta resursiem, normatīvajiem aktiem. Darbā izmantotas šādas pētījuma metodes: 1.SVID analīze; 2.Statistiskā analīze; 3.Salīdzināšanas metode; 4.Monogrāfiska metode; 5.Grafiskās analīze. Projekta izstrāde ir nepieciešama jauna uzņēmuma izveidē, lai varētu noskaidrot, vai projekta ideja ir dzīvotspējīga. Autores projekts ir skaistumkopšanas salona SIA „SK Elega…
Personāla atlases metožu analīze un salīdzināšana uzņēmumā SIA “RIMI Latvia”.
2018
Kvalifikācijas darba zinātniskais vadītājs: lektore, Mg. sc. soc. Inese Pabērza Kvalifikācijas darba temats: Personāla atlases metožu analīze un salīdzināšana uzņēmumā SIA „Rimi Latvia” Kvalifikācijas darba apjoms: 53 lpp, t.sk. 4 tabulas, 9 attēli, 15 pielikumi Kvalifikācijas darbā izmantotie materiāli: Darbā ir izmantota vietējo un ārvalstu autoru literatūra, pētījumi par personāla atlases jautājumiem, publicētie materiāli par SIA „Rimi Latvia” darbinieku meklējumiem, kā arī uzņēmuma nepublicētie materiāli, dažādi interneta resursi un autores veiktās aptaujas dati. Kvalifikācijas darba galvenie rezultāti: Kvalifikācijas darba mērķis ir izpētīt darbinieku atlases procesu mazumtirdzniecības…
Latvijas Vēstures Institūta Žurnāls. 2013, Nr. 3 (88)
2013
Valsts kultūrkapitāla fonds
Heart-type fatty acid binding protein is a sensitive biomarker for early AMI detection in troponin negative patients: a pilot study
2017
Background: Early detecting AMI in individuals presenting to the ED with chest pain continues to be a challenge. cTn is the gold standard for AMI diagnosis but early presenters (<1 hours from symptom onset) maybe cTn negative on admission. We analysed the diagnostic value of h-FABP and hs-TnI in patients presenting to ED with chest pain and no cTnI elevations. Methods: 28 AMI and 28 no-AMI individuals both presented to ED within one hour from pain onset were included. Blood donors were analysed for h-FABP cut-off identification. Among AMI patients, 55% were positive for h-FABP and 34.6% were positive for hs-TnI (p = .015), thus 21% were positive only for h-FABP. The diagnostic accuracy w…
Thermo- and photo-modulation of exciplex fluorescence in a 3D spin crossover Hofmann-type coordination polymer
2018
[EN] The search for bifunctional materials showing synergies between spin crossover (SCO) and luminescence has attracted substantial interest since they could be promising platforms for new switching electronic and optical technologies. In this context, we present the first three-dimensional Fe-II Hofmann-type coordination polymer exhibiting SCO properties and luminescence. The complex {Fe-II(bpben)[Au(CN)(2)]}@pyr (bpben = 1,4-bis(4-pyridyl)benzene) functionalized with pyrene (pyr) guests undergoes a cooperative multi-step SCO, which has been investigated by single crystal X-ray diffraction, single crystal UV-Vis absorption spectroscopy, and magnetic and calorimetric measurements. The resu…
Value of insoluble PABPN1 accumulation in the diagnosis of oculopharyngeal muscular dystrophy.
2019
Background and purpose The aim was to assess the value of insoluble PABPN1 muscle fibre nuclei accumulation in the diagnosis of atypical cases of oculopharyngeal muscular dystrophy (OPMD). Methods Muscle biopsies from a selected cohort of 423 adult patients from several Italian neuromuscular centres were analysed by immunofluorescence: 30 muscle biopsies of genetically proven OPMD, 30 biopsies from patients not affected by neuromuscular disorders, 220 from genetically undiagnosed patients presenting ptosis or swallowing disturbances, progressive lower proximal weakness and/or isolated rimmed vacuoles at muscle biopsy and 143 muscle biopsies of patients affected by other neuromuscular diseas…
El fracaso en la resolución de problemas de Física : una investigación orientada por nuevos supuestos
1988
Resumen basado en el de la publicación Resumen en inglés Se muestra un intento de cuestionar la forma habitual de enseñar la resolución de problemas y elaborar estrategias más efectivas teóricamente basadas en las propuestas. Se incluyen algunos resultados de las aplicaciones de nuevas orientaciones. ESP
A TR-FRET based functional assay for screening activators of CARM1
2013
Epigenome is an emerging field that demands selective cell-permeable chemical probes to perturb, especially in vivo, the activity of specific enzymes involved in modulating the epigenetic codes. Coactivator Associated Arginine (R) Methyltransferase 1 (CARM1) is a coactivator of estrogen receptor α (ERα), the main target in human breast cancer. We previously showed that overexpression of CARM1 by two-fold in MCF7 breast cancer cells increased the expression of ERα-target genes involved in differentiation and reduced cell proliferation, leading to the hypothesis that activating CARM1 by chemical activators may be therapeutically effective in breast cancer. Selective, potent, cell-permeable CA…
Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes.
2020
Background: Naturally occurring variation in Membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), encoding for an enzyme involved in phosphatidylinositol acyl-chain remodelling, has been associated with fatty liver and hepatic disorders. Here, we examined the relationship between hepatic Mboat7 down-regulation and fat accumulation. Methods: Hepatic MBOAT7 expression was surveyed in 119 obese individuals and in experimental models. MBOAT7 was acutely silenced by antisense oligonucleotides in C57Bl/6 mice, and by CRISPR/Cas9 in HepG2 hepatocytes. Findings: In obese individuals, hepatic MBOAT7 mRNA decreased from normal liver to steatohepatitis, independently of diabetes, inflammatio…