Search results for "Alternative methods"

Comparison of the whole slide imaging and conventional light microscopy in the grading of oral epithelial dysplasia: a multi-institutional study

2020

Made available in DSpace on 2021-06-25T11:48:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Background: Whole Slide Imaging (WSI) is an alternative method to light microscopy (LM). However, few studies have compared the diagnostic agreement between WSI and LM, especially to grade oral epithelial dysplasia (OED). The purpose of this study was to evaluate the variability in grading OED by the World Health Organization grading system, using WSI and conventional LM, and to investigate whether the access to clinical information, and psychologic or phy…

Valoración de la ingesta dietética a nivel poblacional mediante cuestionarios individuales: sombras y luces metodológicas

2007

El desarrollo de la moderna metodología necesaria para caracterizar con rigor la ingesta de individuos y poblaciones data de hace sólo dos décadas, cuando germinó la epidemiología nutricional. La razón del carácter reciente de esta disciplina radica en el hecho de que la valoración de la ingesta dietética a nivel poblacional presenta retos complejos, que sólo van siendo superados a medida que investigamos y mejoramos los instrumentos metodológicos disponibles. En el presente artículo se revisan los métodos alternativos para estimar la ingesta de alimentos y nutrientes en los individuos. Tras una sucinta descripción de los métodos indirectos y directos de valoración del consumo alimentario, …

Non-conventional methods and media for the activation and manipulation of carbon nanoforms

2013

Very often, chemical transformations require tedious and long procedures, which, sometimes, can be avoided using alternative methods and media. New protocols, enabling us to save time and solvents, allow us also to explore new reaction profiles. This Tutorial Review focuses on the physical and chemical behavior of carbon nanoforms, CNFs (fullerenes, nanotubes, nanohorns, graphene, etc.) when non-conventional methods and techniques, such as microwave irradiation, mechano-chemistry or highly ionizing radiations are employed. In addition, the reactivity of CNFs in non-conventional media such as water, fluorinated solvents, supercritical fluids, or ionic liquids is also discussed.

Do bank voles (Myodes glareolus) trapped in live and lethal traps show differences in tick burden?

2020

In studies assessing tick abundance, the use of live traps to capture and euthanize rodent hosts is a commonly used method to determine their burden. However, captive animals can experience debilitating or fatal capture stress as a result prior to collection. An alternative method is the use of lethal traps, but this can potentially lead to tick drop-off between the time of capture and collection. In this study, in order to determine whether subjecting animals to capture stress is inevitable, we tested the difference in sheep tick (Ixodes ricinus) larval burdens between bank voles (Myodes glareolus) captured alive and euthanized, and lethally trapped bank voles. During 2017 and 2018, 1318 b…

Use of self-organizing maps for analyzing the behavior of canines displaced towards midline under interceptive treatment

2017

Background Displaced maxillary permanent canine is one of the more frequent findings in canine eruption process and it’s easy to be outlined and early diagnosed by means of x-ray images. Late diagnosis frequently needs surgery to rescue the impacted permanent canine. In many cases, interceptive treatment to redirect canine eruption is needed. However, some patients treated by interceptive means end up requiring fenestration to orthodontically guide the canine to its normal occlusal position. It would be interesting, therefore, to discover the dental characteristics of patients who will need additional surgical treatment to interceptive treatment. Material and Methods To study the dental cha…

Comparison of segmental-dependent permeability in human and in situ perfusion model in rat.

2017

Abstract Nowadays, alternative methods have been developed to predict intestinal permeability values in human as in vitro, in situ or ex vivo methods. They were developed by the necessity to avoid the problems of the human permeability experiments. However, determination of human permeability is needed to properly validate the alternative methods. For this reason, recently, Dahlgren et al. published an indirect method based on a deconvolution technique to estimate the human permeability in different gastrointestinal segments (jejunum, ileum and colon). Therefore, the objective of this research was to demonstrate that Doluisio technique is a useful method to predict the human permeability in…

Comparative experimental analysis on the compressive behaviour of masonry columns strengthened by FRP, BFRCM or steel wires

2017

Abstract In the last decade, several studies have investigated the application of Fibre Reinforced Polymer (FRP) wraps to masonry piers in order to provide a confinement effect and enhance compressive strength and ductility. Although this technique has proved to be quite effective, various drawbacks arise when organic resins are used to bind fibres. To solve these problems, different techniques have been developed to be used as alternative methods for enhancing the structural performances of weak masonry columns. Among these, the use of Basalt Fibre Reinforced Cementitious Matrix (BFRCM) wrapping, or the application of steel wires at mortar joints. This paper presents the results of an expe…

Alternative Methods for Skin Sensitisation Testing

1996

Paper vs. Pixel: Can We Use a Pen-and-Paper Method to Measure Athletes' Implicit Doping Attitude?

2017

Doping attitude is an individual’s subjective evaluation (e.g., good or bad, useful or useless) toward the use of prohibited performance-enhancing substances or methods in sports. Research on doping attitude has traditionally relied on self-report questionnaire methods to measure the construct (Ntoumanis et al., 2014; Chan et al., 2015). However, as doping in sport is illegal (World AntiDoping Agency, 2015) and perceived as socially unacceptable, athletes who hold positive attitudes toward doping are less likely to reveal them to others. As a result explicit measures of doping attitude are susceptible to potential bias as athletes may respond in a socially desirable fashion (Petróczi and Ai…

An LD50model for predicting psychotropic drug toxicity using biopartitioning micellar chromatography

2001

The LD50 determination is the main way to measure the acute toxicity of all types of substances. At the present time, however, there is increasing opposition to the use of living animals in research and testing activities from animal rights groups as well as some scientists. Nevertheless, the need to have a tool for estimating the potential toxicity of new compounds for human consumption has encouraged the development of alternative methods. Under adequate conditions, the partitioning in micellar liquid chromatography can describe the drug biopartitioning. We have named this chromatographic system biopartitioning micellar chromatography (BMC). In this paper, an LD50 QRAR model developed for…