Search results for "Analysis method"
showing 10 items of 713 documents
Characteristic Topological Features of Promoter Capture Hi-C Interaction Networks
2020
Current Hi-C technologies for chromosome conformation capture allow to understand a broad spectrum of functional interactions between genome elements. Although significant progress has been made into analysis of Hi-C data to identify the biologically significant features, many questions still remain open. In this paper we describe analysis methods of Hi-C (specifically PCHi-C) interaction networks that are strictly focused on topological properties of these networks. The main questions we are trying to answer are: (1) can topological properties of interaction networks for different cell types alone be sufficient to distinguish between these types, and what the most important of such propert…
Cadmium and lead in infant cereals — electrothermal-atomic absorption spectroscopic determination
1999
Because infant cereals are an important component of the infant diet from the fourth month of life onwards and therefore contribute to the dietetic intake of metals by infants, cadmium and lead were measured in samples of cereals commercially available in Spain. For this purpose an electrothermal atomic absorption (ET-AAS) method for determining cadmium and lead in these products was studied. The ET-AAS instrumental conditions and temperature/time furnace program were selected. The analytical parameters of the method (linearity, detection and quantification limits and precision) show its usefulness in measuring cadmium and lead in infant cereal products. The method was applied to eight diff…
Effects of seniority, gender and geography on the bibliometric output and collaboration networks of European Research Council (ERC) grant recipients.
2019
Assessing the success and performance of researchers is a difficult task, as their grant output is influenced by a series of factors, including seniority, gender and geographical location of their host institution. In order to assess the effects of these factors, we analysed the publication and citation outputs, using Scopus and Web of Science, and the collaboration networks of European Research Council (ERC) starting (junior) and advanced (senior) grantees. For this study, we used a cohort of 355 grantees from the Life Sciences domain of years 2007-09. While senior grantees had overall greater publication output, junior grantees had a significantly greater pre-post grant award increase in …
Bounding Techniques and Their Application to Simplified Plastic Analysis of Structures
1990
In the framework of the simplified analysis methods for elastoplastic analysis problems, the bounding techniques possess an important role. A class of these techniques, based on the so-called perturbation method, are here presented with reference to finite element discretized structures. A general bounding principle is presented and its applications are illustrated by means of numerical examples.
A Study on Engineering Freshman Conceptual Understanding of Newtonian Mechanics
2021
Force concept inventory is a multiple-choice questionnaire commonly used to assess students’ conceptual understanding of Newtonian mechanics. We here show that a cluster analysis method can be used to study student answers to the force concept inventory to investigate their understanding of Newtonian mechanics and provide new insights into the use of the force concept inventory. We identi- fied groups of students characterized by similar correct answers as well as by non- correct answers to the questionnaire, whose analysis allowed us to highlight student misconceptions/non-normative conceptions. Such an analysis of student answers gave us insights into the relationships between the student…
SMART: Unique splitting-while-merging framework for gene clustering
2014
© 2014 Fa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Successful clustering algorithms are highly dependent on parameter settings. The clustering performance degrades significantly unless parameters are properly set, and yet, it is difficult to set these parameters a priori. To address this issue, in this paper, we propose a unique splitting-while-merging clustering framework, named "splitting merging awareness tactics" (SMART), which does not require any a priori knowledge of either the number …
The Global Research Collaboration of Network Meta-Analysis: A Social Network Analysis
2016
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Dynamics of two competing species in the presence of Lévy noise sources
2010
We consider a Lotka-Volterra system of two competing species subject to multiplicative alpha-stable Lévy noise. The interaction parameter between the species is a random process which obeys a stochastic differential equation with a generalized bistable potential in the presence both of a periodic driving term and an additive alpha-stable Lévy noise. We study the species dynamics, which is characterized by two different regimes, exclusion of one species and coexistence of both. We find quasi-periodic oscillations and stochastic resonance phenomenon in the dynamics of the competing species, analysing the role of the Lévy noise sources.
The pharmacological and non-pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: A systematic review wi…
2017
Background Attention deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed psychiatric disorders in childhood. A wide variety of treatments have been used for the management of ADHD. We aimed to compare the efficacy and safety of pharmacological, psychological and complementary and alternative medicine interventions for the treatment of ADHD in children and adolescents. Methods and findings We performed a systematic review with network meta-analyses. Randomised controlled trials (≥ 3 weeks follow-up) were identified from published and unpublished sources through searches in PubMed and the Cochrane Library (up to April 7, 2016). Interventions of interest were pharmacolo…
Zinc isotope variations in archeological human teeth (Lapa do Santo, Brazil) reveal dietary transitions in childhood and no contamination from gloves
2020
International audience; Zinc (Zn) isotope ratios of dental enamel are a promising tracer for dietary reconstruction in archeology, but its use is still in its infancy. A recent study demonstrated a high risk of Zn contamination from nitrile, and latex gloves used during chemical sample preparation. Here we assess the potential impact of the use of such gloves during enamel sampling on the Zn isotope composition of teeth from a population of early Holocene hunter gatherers from Lapa do Santo, Lagoa Santa, Minas Gerais, Brazil. We first examined the amount of Zn and its isotopic composition released from the gloves used in this study by soaking them in weak nitric acid and water. We compared …