Search results for "Analysis method"

showing 10 items of 713 documents

Perfusion of surgical cavity wall enhancement in early post-treatment MR imaging may stratify the time-to-progression in glioblastoma

2017

Objective To determine if perfusion in surgical cavity wall enhancement (SCWE) obtained in early post-treatment MR imaging can stratify time-to-progression (TTP) in glioblastoma. Materials and methods This study enrolled 60 glioblastoma patients with more than 5-mm-thick SCWEs as detected on contrast-enhanced MR imaging after concurrent chemoradiation therapy. Two independent readers categorized the shape and perfusion state of SCWEs as nodular or non-nodular and as having positive or negative perfusion compared with the contralateral grey matter on arterial spin labeling (ASL). The perfusion fraction on ASL within the contrast-enhancing lesion was calculated. The independent predictability…

MaleCentral Nervous Systemlcsh:MedicineContrast MediaKaplan-Meier EstimatePathology and Laboratory MedicineNervous SystemDiagnostic Radiology030218 nuclear medicine & medical imaging0302 clinical medicineFunctional Magnetic Resonance ImagingMedicine and Health SciencesBlastomasMedicinelcsh:ScienceNeurological TumorsBrain MappingMultidisciplinarymedicine.diagnostic_testBrain NeoplasmsRadiology and ImagingChemoradiotherapyCombined Modality TherapyMagnetic Resonance ImagingDacarbazinePerfusionmedicine.anatomical_structureOncologyNeurology030220 oncology & carcinogenesisDisease ProgressionFemaleAnatomymedicine.symptomPerfusionResearch Articlemedicine.drugImaging TechniquesSurgical and Invasive Medical ProceduresNeuroimagingGrey matterResearch and Analysis MethodsLesion03 medical and health sciencesSigns and SymptomsText miningDiagnostic MedicineArterial Spin LabellingImage Interpretation Computer-AssistedTemozolomideHumansAgedTemozolomideSurgical Resectionbusiness.industryProportional hazards modellcsh:RCancers and NeoplasmsBiology and Life SciencesMagnetic resonance imagingmedicine.diseaseLesionslcsh:QSpin LabelsGlioblastomabusinessNuclear medicineGlioblastoma MultiformeNeuroscienceGlioblastomaPLOS ONE
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5th generation vs 4th generation troponin T in predicting major adverse cardiovascular events and all-cause mortality in patients hospitalized for no…

2020

Objective The frequency and implications of an elevated cardiac troponin (4th or 5th generation TnT) in patients outside of the emergency department or presenting with non-cardiac conditions is unclear. Methods Consecutive patients aged 18 years or older admitted for a primary non-cardiac condition who had the 4th generation TnT drawn had the 5th generation TnT run on the residual blood sample. Primary and secondary outcomes were all-cause mortality (ACM) and major adverse cardiovascular events (MACE) respectively at 1 year. Results 918 patients were included (mean age 59.8 years, 55% male) in the cohort. 69% had elevated 5th generation TnT while 46% had elevated 4th generation TnT. 5th ge…

MaleCritical Care and Emergency MedicineEpidemiologyMyocardial InfarctionCardiovascular Medicine030204 cardiovascular system & hematologyBiochemistryElectrocardiographyMedical Conditions0302 clinical medicineMedicine and Health Sciences030212 general & internal medicineMyocardial infarctionImmunoassayMultidisciplinarymedicine.diagnostic_testbiologyTroponin TQRMiddle Agedmusculoskeletal systemTroponinHospitalizationBioassays and Physiological AnalysisCardiovascular DiseasesCohortCardiologyMedicineFemaleResearch ArticleCohort studymedicine.medical_specialtyDeath RatesScienceCardiologyResearch and Analysis Methods03 medical and health sciencesTroponin TPopulation MetricsPredictive Value of TestsInternal medicinemedicineHumansMortalityPopulation Biologybusiness.industryElectrophysiological TechniquesBiology and Life SciencesProteinsEmergency departmentCardiovascular Disease Riskmedicine.diseaseTroponinCytoskeletal ProteinsMedical Risk Factorsbiology.proteinCardiac ElectrophysiologybusinessElectrocardiographyMacePLoS ONE
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Efficacy and safety of decompressive craniectomy with non-suture duraplasty in patients with traumatic brain injury.

2020

AbstractBackgroundDecompressive craniectomy is an important surgical treatment for patients with severe traumatic brain injury (TBI). Several reports have been published on the efficacy of non-watertight sutures in duraplasty performed in decompressive craniectomy. This study aims to evaluate the effectiveness of dura closure without sutures (non-suture duraplasty) in decompressive craniectomy for TBI.MethodsOne hundred and six patients were enrolled at a single trauma center between January 2017 and December 2018. We retrospectively collected the data and classified the patients into non-suture and suture duraplasty craniectomy groups. We compared the characteristics of patients and their …

MaleCritical Care and Emergency MedicineTraumatic Brain InjuryPhysiologymedicine.medical_treatmentBlood Loss SurgicalGlasgow Outcome ScaleNervous SystemVascular MedicineDiagnostic RadiologyNervous System Procedures0302 clinical medicineSuture (anatomy)AntibioticsBrain Injuries TraumaticMedicine and Health SciencesSurgical treatmentTomographyTrauma MedicineCerebrospinal FluidMultidisciplinaryAntimicrobialsRadiology and ImagingGlasgow Outcome ScaleTrauma centerQRDrugsMiddle AgedSevere Blood LossCranioplastySutureless Surgical ProceduresBody FluidsTreatment OutcomeMedicineFemaleDecompressive craniectomyAnatomyTraumatic InjuryResearch ArticleAdultDecompressive Craniectomymedicine.medical_specialtyImaging TechniquesTraumatic brain injuryScienceOperative TimeTrauma SurgerySurgical and Invasive Medical ProceduresNeuroimagingHemorrhageResearch and Analysis MethodsMicrobiologyCranioplasty03 medical and health sciencesSigns and SymptomsBlood lossDiagnostic MedicineMicrobial ControlmedicineHumansIn patientRetrospective StudiesPharmacologybusiness.industryBiology and Life Sciences030208 emergency & critical care medicinemedicine.diseaseComputed Axial TomographySurgeryDura MaterClinical MedicinebusinessNeurotraumaTrauma surgery030217 neurology & neurosurgeryNeurosciencePLoS ONE
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Memorable Experiences with Sad Music : Reasons, Reactions and Mechanisms of Three Types of Experiences

2016

Reactions to memorable experiences of sad music were studied by means of a survey administered to a convenience (N = 1577), representative (N = 445), and quota sample (N = 414). The survey explored the reasons, mechanisms, and emotions of such experiences. Memorable experiences linked with sad music typically occurred in relation to extremely familiar music, caused intense and pleasurable experiences, which were accompanied by physiological reactions and positive mood changes in about a third of the participants. A consistent structure of reasons and emotions for these experiences was identified through exploratory and confirmatory factor analyses across the samples. Three types of sadness …

MaleCultural anthropologySorrowlcsh:MedicineSocial SciencesAnxietyDevelopmental psychologyCultural Anthropology0302 clinical medicineMathematical and Statistical TechniquesCognitionLearning and MemoryPsychologylcsh:Sciencemedia_commonMultidisciplinaryMusic psychologyPhysics05 social sciencesMusic PerceptionMiddle AgedhumanitiesSadnessMusic perceptionPhysical Sciencesta6131AnxietySensory PerceptionFemalemedicine.symptomPsychologyFactor AnalysissadnessStatistics (Mathematics)Research ArticleAdultMusic therapyAdolescentmedia_common.quotation_subjectResearch and Analysis Methodsemotionsbehavioral disciplines and activities050105 experimental psychology03 medical and health sciencesYoung AdultMemorymedicineHumans0501 psychology and cognitive sciencesmusicStatistical MethodsMusic TherapyAgedMusic Cognitionlcsh:RCognitive PsychologyBiology and Life SciencesAcousticsMoodAnthropologyCognitive Sciencelcsh:QexperiencesBioacoustics030217 neurology & neurosurgeryMathematicsNeuroscienceBereavementPLoS ONE
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Smartphone Addiction Inventory (SPAI): Translation, adaptation and validation of the tool in Spanish adult population

2018

The wide functionality and the vast range of attributes offered by smartphones has led to a substantial increase in the average amount of time these devices are used per day. An excessive use of these tools has been shown to result in symptomatology similar to psychological disorders caused by substance addiction. In Spain, smartphone use has risen exponentially but the effects of this increase remain unclear. Therefore, an instrument is required to help determine the extent of smartphone addiction in the Spanish population. The Smartphone Addiction Inventory (SPAI) is a valid and reliable mean to identify and measure smartphone addiction and so, the aim of this research is the translation …

MaleCultureSocial Scienceslcsh:Medicine050109 social psychologyGeographical locationsMathematical and Statistical Techniques0302 clinical medicineSociologyGoodness of fitSurveys and QuestionnairesMedicine and Health SciencesPsychologyPublic and Occupational Healthlcsh:ScienceReliability (statistics)media_commonMultidisciplinaryStatistics05 social sciencesDependència (Psicologia)Middle AgedConfirmatory factor analysisEuropePhysical SciencesEngineering and TechnologyFemaleSmartphonemedicine.symptomPsychologyFactor AnalysisResearch ArticleClinical psychologyAdultBehavioral addictionAdolescentPsychometricsSubstance-Related Disordersmedia_common.quotation_subjectEquipmentAddictionResearch and Analysis MethodsYoung Adult03 medical and health sciencesCronbach's alphaCross-Cultural StudiesMental Health and PsychiatrymedicineHumans0501 psychology and cognitive sciencesEuropean UnionStatistical MethodsAdaptation (computer science)Communication EquipmentAddictionSubstance Addictionlcsh:RBiology and Life SciencesModels TheoreticalAbstinence030227 psychiatryBehavior AddictiveSpainBehavioral AddictionAge GroupsTelèfon mòbilPeople and PlacesPopulation Groupingslcsh:QSelf ReportCell PhonesMathematics
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Comparison of Diffusion MRI Acquisition Protocols for the In Vivo Characterization of the Mouse Spinal Cord: Variability Analysis and Application to …

2016

Diffusion-weighted Magnetic Resonance Imaging (dMRI) has relevant applications in the microstructural characterization of the spinal cord, especially in neurodegenerative diseases. Animal models have a pivotal role in the study of such diseases; however, in vivo spinal dMRI of small animals entails additional challenges that require a systematical investigation of acquisition parameters. The purpose of this study is to compare three acquisition protocols and identify the scanning parameters allowing a robust estimation of the main diffusion quantities and a good sensitivity to neurodegeneration in the mouse spinal cord. For all the protocols, the signal-to-noise and contrast-to noise ratios…

MaleDTI-MRI spinal cord ALSPathologylcsh:MedicineSignal-To-Noise RatioNervous System030218 nuclear medicine & medical imagingDiagnostic RadiologyDiffusionMice0302 clinical medicineSuperoxide Dismutase-1Materials PhysicsMedicine and Health SciencesImage Processing Computer-AssistedAmyotrophic lateral sclerosisDiffusion (business)lcsh:ScienceMicrostructureMusculoskeletal SystemBrain MappingMultidisciplinarymedicine.diagnostic_testRadiology and ImagingPhysicsAnimal ModelsCondensed Matter PhysicsMagnetic Resonance Imagingmedicine.anatomical_structureDiffusion Tensor ImagingSpinal CordPhysical SciencesAnatomyResearch Articlemedicine.medical_specialtyImaging TechniquesBrain MorphometryMaterials ScienceMaterial PropertiesNeuroimagingMouse ModelsMice TransgenicResearch and Analysis Methods03 medical and health sciencesModel OrganismsDiagnostic MedicineFractional anisotropymedicineAnimalsSensitivity (control systems)AllelesProtocol (science)business.industryAmyotrophic Lateral Sclerosislcsh:RBiology and Life SciencesReproducibility of ResultsMagnetic resonance imagingmedicine.diseaseSpinal cordSpineNeuroanatomyDisease Models AnimalDiffusion Magnetic Resonance ImagingMutationAnisotropylcsh:Qbusiness030217 neurology & neurosurgeryBiomedical engineeringDiffusion MRINeurosciencePLoS ONE
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Longitudinal changes in physical activity, sedentary behavior and body mass index in adolescence: Migrations towards different weight cluster

2016

This study examined longitudinal changes in physical activity, sedentary behavior and body mass index in adolescents, specifically their migrations towards a different weight cluster. A cohort of 755 adolescents participated in a three-year study. A clustering Self-Organized Maps Analysis was performed to visualize changes in subjects' characteristics between the first and second assessment, and how adolescents were grouped. Also a classification tree was used to identify the behavioral characteristics of the groups that changed their weight cluster. Results indicated that boys were more active and less sedentary than girls. Boys were especially keen to technological-based activities while …

MaleDecision AnalysisPhysiologyHealth Behaviorlcsh:MedicineOverweightAdolescentsBody Mass Index0302 clinical medicineAnimal CellsMedicine and Health SciencesPublic and Occupational HealthLongitudinal Studies030212 general & internal medicineYoung adultlcsh:ScienceChildNeuronsMultidisciplinarySedentary behaviorPhysiological ParametersResearch DesignCohortEngineering and TechnologyFemaleCellular Typesmedicine.symptomPsychologyManagement EngineeringResearch ArticleAdultmedicine.medical_specialtyAdolescentMotor ActivityResearch and Analysis MethodsDisease clusterYoung Adult03 medical and health sciencesThinnessmedicineHumansObesityExercise physiologyExerciseBehaviorlcsh:RBody WeightDecision TreesBiology and Life SciencesCell BiologyPhysical Activity030229 sport sciencesOverweightmedicine.diseaseObesitySpainAge GroupsCellular NeurosciencePeople and PlacesPhysical therapylcsh:QPopulation GroupingsSedentary BehaviorBody mass indexNeuroscienceDemographyPLOS ONE
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The biometric antecedents to happiness

2017

It has been suggested that biological markers are associated with human happiness. We contribute to the empirical literature by examining the independent association between various aspects of biometric wellbeing measured in childhood and happiness in adulthood. Using Young Finns Study data (n = 1905) and nationally representative linked data we examine whether eight biomarkers measured in childhood (1980) are associated with happiness in adulthood (2001). Using linked data we account for a very rich set of confounders including age, sex, body size, family background, nutritional intake, physical activity, income, education and labour market experiences. We find that there is a negative rel…

MaleEmotionsHappinessSocial Scienceslcsh:MedicineBlood Pressure050109 social psychologyBiochemistryVascular MedicineDevelopmental psychologyPregnancyMedicine and Health ScienceshappinessPsychologyEthnicitiesPublic and Occupational Health050207 economicsChildlcsh:Scienceta512Finlandmedia_commonMultidisciplinary05 social sciencesConfoundingAge FactorsBiometricsAdipose TissueChild PreschoolFemaleAnatomyPsychologyResearch ArticleAdultAdolescentBiometrics515 Psychologymedia_common.quotation_subjectPhysical activityResearch and Analysis MethodsSex FactorsComputational Techniques0502 economics and businessAdultsHumansPersonality0501 psychology and cognitive sciencesAssociation (psychology)Triglyceridesbiometric antecedentslcsh:RBiology and Life SciencesPhysical Activityta3121ta3123Biological TissueAge GroupsNegative relationshipPeople and PlacesHappinessPopulation Groupingslcsh:QLiterature studyBiomarkersFinnsFollow-Up StudiesPLOS ONE
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Qualitative analysis of the Best Possible Self intervention: Underlying mechanisms that influence its efficacy.

2019

BackgroundThe Best Possible Self is a Positive Psychology Intervention which asks participants to write down about themselves in their best possible future. Previous studies have shown its efficacy to enhance wellbeing, but the mechanisms that underlie its efficacy are still unknown.ObjectiveThe aim of this study was to analyze the content of the essays of the BPS intervention and to examine how this content was related to the efficacy of the intervention to increase positive affect.MethodParticipants (N = 78) were randomized to either the Best Possible Self condition, or one of two variants of the intervention: one's best self in the present, and one's best self in the past. Qualitative an…

MaleEmotionsPsychological interventionSocial Sciences050109 social psychologyDevelopmental psychologyMathematical and Statistical TechniquesLearning and MemorySociologyMedicine and Health SciencesPsychologyHuman Familiesmedia_commonMultidisciplinaryStatistics05 social sciencesQRMetaanalysisSelf EfficacyPsychology PositivePhysical SciencesRegression AnalysisMedicineFemalePositive psychologyPsychologyResearch ArticleAdultMediation (statistics)Adolescentmedia_common.quotation_subjectScienceQualitative propertyResearch and Analysis MethodsInterpersonal Relationships050105 experimental psychologyHuman LearningInterpersonal relationshipIntervention (counseling)Mental Health and PsychiatryHumansLearning0501 psychology and cognitive sciencesStatistical MethodsSelf-efficacyCognitive PsychologyBiology and Life SciencesCollective Human BehaviorHappinessCognitive ScienceMathematicsNeurosciencePLoS ONE
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Regional variations in Helicobacter pylori infection, gastric atrophy and gastric cancer risk: The ENIGMA study in Chile.

2020

International audience; Background: Regional variations in gastric cancer incidence are not explained by prevalence of Helicobacter pylori, the main cause of the disease, with several areas presenting high H. pylori prevalence but low gastric cancer incidence. The IARC worldwide H. pylori prevalence surveys (ENIGMA) aim at systematically describing age and sex-specific prevalence of H. pylori infection around the world and generating hypotheses to explain regional variations in gastric cancer risk.Methods: We selected age- and sex-stratified population samples in two areas with different gastric cancer incidence and mortality in Chile: Antofagasta (lower rate) and Valdivia (higher rate). Pa…

MaleEpidemiologyPathology and Laboratory MedicineGastroenterologyGeographical locations0302 clinical medicineRisk FactorsHelicobacterEpidemiology of cancerPrevalenceMedicine and Health SciencesMedicineChileEnzyme-Linked ImmunoassaysYoung adultChildeducation.field_of_studyMultidisciplinary[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologybiologyCancer Risk FactorsStomachQRMiddle AgedBacterial Pathogens3. Good healthOncologyMedical MicrobiologyChild Preschool030220 oncology & carcinogenesisMedicineFemale030211 gastroenterology & hepatologyPathogensCancer EpidemiologyResearch ArticleAdultmedicine.medical_specialtyAdolescentSciencePopulationResearch and Analysis MethodsMicrobiologyHelicobacter InfectionsYoung Adult03 medical and health sciencesSigns and SymptomsAtrophyStomach NeoplasmsInternal medicineGastrointestinal TumorsHumansCagASeroprevalenceImmunoassayseducationMicrobial PathogensAgedChile (Country)Bacteriabusiness.industryOrganismsInfantBiology and Life SciencesCancers and NeoplasmsCancerSouth AmericaHelicobacter pylorimedicine.diseasebiology.organism_classificationHelicobacter Pyloridigestive system diseasesGastric CancerAge GroupsMedical Risk FactorsPeople and PlacesImmunologic TechniquesPopulation GroupingsClinical MedicineAtrophybusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyPLoS ONE
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