Search results for "Analysis method"

showing 10 items of 713 documents

Effects of moderate vs. high iso-inertial loads on power, velocity, work and hamstring contractile function after flywheel resistance exercise.

2019

Flywheel iso-inertial training has been shown to positively affect muscular strength and sports performance (e.g. agility). However, implementing such eccentrically-biased training during a microcycle needs to be carefully planned due to its purported effects on the neuromuscular system that can last for hours/days post-exercise. This study aimed at using tensiomyography to verify the effects of different inertias during the hip extension exercise on the contractile function of biceps femoris and semitendinosus muscles of the dominant leg for up to 72 hours post-exercise. Thirty participants (24.4 ± 3.4 years) were divided into 0.075 or 0.1 kg·m2 inertia groups and a control group. Magnitud…

Muscle PhysiologyInertiaPhysiologyBiceps0302 clinical medicineAnimal CellsMedicine and Health SciencesPublic and Occupational HealthSemitendinosus muscleMusculoskeletal System2406.04 BiomecánicaMultidisciplinaryPhysicsMusclesQRClassical MechanicsMuscle AnalysisSports ScienceBioassays and Physiological AnalysisPhysical SciencesStrength TrainingLegsMedicineCellular TypesAnatomymedicine.symptomResearch ArticleMuscle ContractionMuscle contractionmedicine.medical_specialtyStrength trainingScienceSlow-Twitch Muscle FibersResearch and Analysis MethodsMuscle FibersTensiomyographyFlywheelPelvisMotion03 medical and health sciencesPhysical medicine and rehabilitationmedicineSports and Exercise MedicineExerciseHipbusiness.industryBiology and Life SciencesCell BiologyPhysical Activity030229 sport sciencesSkeletal Muscle FibersMuscle stiffnessPhysical FitnessBody Limbs2411.06 Fisiología del Ejerciciobusiness030217 neurology & neurosurgeryHamstringPloS one
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Effect of radiofrequency and pelvic floor muscle training in the treatment of women with vaginal laxity: A study protocol

2021

Background Vaginal laxity is an underreported condition that negatively affects women’s sexual function and their relationships. Evidence-based studies are needed to better understand this complaint and to discuss its treatment options. Thus, we present a study protocol to compare the effect of radiofrequency and pelvic floor muscle training in the treatment of women with complaints of vaginal laxity. Methods/Design This is a prospective, parallel-group, two-arm, randomized clinical trial (Registry: RBR-2zdvfp–REBEC). Participants will be randomly assigned to one of the two groups of intervention (Radiofrequency or Pelvic Floor Muscle Training). The study will be performed in the Urogyneco…

Muscle PhysiologyMuscle FunctionsPhysiologyRadio WavesMaternal HealthAmbulatory Care Facilitieslaw.inventionUrogynecologyStudy ProtocolLabor and DeliveryRandomized controlled trialQuality of lifelawMedicine and Health SciencesOutpatient clinicRegistriesMultidisciplinaryQRObstetrics and Gynecologymedicine.anatomical_structureVaginaMedicineMuscle Contractionmedicine.medical_specialtyDrug Research and DevelopmentUrologyScienceSurgical and Invasive Medical ProceduresResearch and Analysis MethodsPelvic Floor MuscleIntervention (counseling)medicineClinical TrialsOutpatient ClinicsPharmacologyIncontinencebusiness.industryBiology and Life SciencesPelvic FloorRandomized Controlled TrialsHealth CareHealth Care FacilitiesPhysical therapyQuality of LifeBirthWomen's HealthSelf ReportClinical MedicineSexual functionbusinessPLoS ONE
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Progressive active mobilization with dose control and training load in critically ill patients (PROMOB): Protocol for a randomized controlled trial

2020

The dose of progressive active mobilization is still uncertain. The purpose of this study is to identify if the addition of a protocol of progressive active mobilization with dose and training load control to usual care is effective in reducing the length of stay in intensive care unit (ICU) and the improvement of the functioning, incidence of ICU-acquired weakness (ICUAW), mechanical ventilation duration and mortality rate in patients hospitalized in ICU. It is Double-blind randomised clinical trial. The setting for this trial will be medical and surgical ICU of a university hospital. The study participants will be 118 patients aged> 18 years admitted to ICU for less than 72 hours. Partici…

Muscle PhysiologyMuscle FunctionsPhysiologymedicine.medical_treatmentHamstring MusclesKaplan-Meier EstimateQuadriceps Musclelaw.inventionMathematical and Statistical Techniques0302 clinical medicineClinical ProtocolsRandomized controlled triallawMedicine and Health SciencesPublic and Occupational Health030212 general & internal medicineYoung adultRandomized Controlled Trials as TopicMultidisciplinaryMortality rateStatisticsQRMetaanalysisIntensive care unitSports ScienceHospitalsIntensive Care UnitsStrength TrainingPhysical SciencesMedicinemedicine.symptomAdultWeaknessmedicine.medical_specialtyDrug Research and DevelopmentDeath RatesStrength trainingCritical IllnessScienceResearch and Analysis MethodsYoung Adult03 medical and health sciencesDouble-Blind MethodPopulation MetricsRegistered Report ProtocolmedicineHumansClinical TrialsMuscle StrengthSports and Exercise MedicineStatistical MethodsExercisePharmacologyMechanical ventilationPopulation Biologybusiness.industryBiology and Life Sciences030208 emergency & critical care medicinePhysical ActivityLength of StayRespiration ArtificialRandomized Controlled TrialsHealth CareClinical trialPhysical FitnessHealth Care FacilitiesPhysical therapyClinical MedicinebusinessMathematicsPLOS ONE
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Using synchrotrons and XFELs for time-resolved X-ray crystallography and solution scattering experiments on biomolecules

2015

International audience; Time-resolved structural information is key to understand the mechanism of biological processes, such as catalysis and signalling. Recent developments in X-ray sources as well as data collection and analysis methods are making routine time-resolved X-ray crystallography and solution scattering experiments a real possibility for structural biologists. Here we review the information that can be obtained from these techniques and discuss the considerations that must be taken into account when designing a time-resolved experiment.

NanotechnologyElectrons010402 general chemistryCrystallography X-Ray01 natural sciencesCatalysi03 medical and health sciencesStructural BiologyScattering radiationHumansScattering RadiationStructural DynamicMolecular BiologyAnalysis method030304 developmental biologychemistry.chemical_classificationPhysics[PHYS]Physics [physics]0303 health sciencesScatteringBiomoleculeLasersReaction TriggeringSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)0104 chemical sciencesSolutionschemistryX-ray crystallographyAtomic physicsStructural Biology; Structural Dynamics; Catalysis; Reaction TriggeringSynchrotronsCurrent Opinion in Structural Biology
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Invagination of the Sphenoid Sinus Mucosa after Endoscopic Endonasal Transsphenoidal Approach and Its Significance

2016

Objective To describe the clinical features of invagination of the sphenoid sinus mucosa (ISM) and compare them with other similar cases using a visual analog scale (VAS) to assess the various nasal symptoms and to discuss its clinical significance and means of prevention. Study design Retrospective chart review at a tertiary referral center. Methods Between 2010 and 2015, 8 patients who had undergone EETSA surgery displayed postoperative ISM. The comparison group consisted of 147 patients who underwent the same surgical procedures and were diagnosed with the same diseases. Pre- or postoperative paranasal sinus computed tomography (PNS CT) and VAS were performed and subsequently analyzed. R…

Nasal cavityMaleIntracranial PressureVisual Analog ScalePhysiologylcsh:MedicinePituitary neoplasmPathology and Laboratory MedicineNervous System030218 nuclear medicine & medical imagingDiagnostic Radiology0302 clinical medicinePostoperative ComplicationsMedicine and Health Scienceslcsh:ScienceTomographySinus (anatomy)Intracranial pressureMultidisciplinarymedicine.diagnostic_testHeadachesRadiology and ImagingInvaginationMiddle AgedMagnetic Resonance Imagingmedicine.anatomical_structureSella turcicaPituitary GlandFemaleAnatomyNasal CavityPlastic Surgery and Reconstructive TechniquesResearch ArticleAdenomaAdultmedicine.medical_specialtySphenoid SinusVisual analogue scaleImaging TechniquesNeuroimagingSurgical and Invasive Medical ProceduresEndocrine SystemResearch and Analysis Methods03 medical and health sciencesSigns and SymptomsDiagnostic MedicineEndoscopic SurgeryTissue RepairmedicinePressureHumansPituitary NeoplasmsSella TurcicaAgedRetrospective StudiesEndoscopic Sinus SurgeryEndoscopic Plastic Surgerybusiness.industrylcsh:RBiology and Life SciencesEndoscopyOtolaryngological ProceduresSurgeryEndoscopyComputed Axial TomographyNeuroanatomylcsh:QbusinessPhysiological ProcessesTomography X-Ray Computed030217 neurology & neurosurgeryNeurosciencePLoS ONE
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Comparison of HapMap and 1000 genomes reference panels in a large-scale genome-wide association study

2017

An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associated loci when compared to HapMap imputation. In order to assess the improvement of 1000G over HapMap imputation in identifying associated loci, we compared the results of GWA studies of circulating fibrinogen based on the two reference panels. Using both HapMap and 1000G imputation we performed a meta-analysis of 22 studies comprising the same 91,953 individuals. We identified six additional signals using 1000G imputation, while 29 loci were ass…

Netherlands Twin Register (NTR)0301 basic medicineGlycobiologySocial Scienceslcsh:MedicineGenome-wide association study030105 genetics & heredityBiochemistryMathematical and Statistical TechniquesSociologyCell SignalingConsortiaGENETIC-VARIANTSMedicine and Health SciencesIMPUTATIONInternational HapMap Projectlcsh:ScienceGeneticsMultidisciplinaryCOMMON VARIANTSGenomicsMultidisciplinary SciencesINSIGHTSCARDIOVASCULAR-DISEASEPhysical SciencessymbolsScience & Technology - Other TopicsHealth Services ResearchGenomic Signal ProcessingStatistics (Mathematics)Research ArticleSignal TransductionGenotypingSUSCEPTIBILITY LOCIGeneral Science & TechnologyBIOLOGYSingle-nucleotide polymorphismGenomicsHapMap ProjectComputational biologyPRESSUREBiologyResearch and Analysis Methods03 medical and health sciencessymbols.namesakeMD MultidisciplinaryGenome-Wide Association StudiesGeneticsJournal Article/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_HumansStatistical Methods1000 Genomes ProjectMolecular Biology TechniquesMolecular BiologyMETAANALYSISGlycoproteinsScience & Technologylcsh:RHuman GenomeCONSORTIUMBiology and Life SciencesComputational BiologyFibrinogenHuman GeneticsCell BiologyComparative GenomicsGenome AnalysisHealth Care030104 developmental biologyBonferroni correctionlcsh:QHaplotype estimationMathematicsImputation (genetics)Meta-AnalysisGenome-Wide Association Study
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Neutrino interaction classification with a convolutional neural network in the DUNE far detector

2020

The Deep Underground Neutrino Experiment is a next-generation neutrino oscillation experiment that aims to measure CP-violation in the neutrino sector as part of a wider physics program. A deep learning approach based on a convolutional neural network has been developed to provide highly efficient and pure selections of electron neutrino and muon neutrino charged-current interactions. The electron neutrino (antineutrino) selection efficiency peaks at 90% (94%) and exceeds 85% (90%) for reconstructed neutrino energies between 2–5 GeV. The muon neutrino (antineutrino) event selection is found to have a maximum efficiency of 96% (97%) and exceeds 90% (95%) efficiency for reconstructed neutrino…

Neutrino Oscillations. Neutrino detectors.Physics - Instrumentation and DetectorsPhysics::Instrumentation and Detectorsfar detector01 natural sciencesPhysics Particles & FieldsHigh Energy Physics - Experimentcharged currentHigh Energy Physics - Experiment (hep-ex)[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Particle Physics ExperimentsMuon neutrinoneutrino/e: particle identificationNeutrino detectorsDetectors and Experimental Techniquesphysics.ins-detCharged currentneutrino: interactionInformáticaPhysicsTelecomunicacionesNeutrino oscillationsPhysicsNeutrino interactions neural network DUNE Deep Underground Neutrino ExperimentInstrumentation and Detectors (physics.ins-det)Experiment (hep-ex)Neutrino detectorPhysical SciencesCP violationNeutrinoParticle Physics - ExperimentParticle physicsdata analysis method530 Physicsneural networkAstrophysics::High Energy Astrophysical PhenomenaCONSERVATIONFOS: Physical sciencesAstronomy & AstrophysicsDeep Learningneutrino: deep underground detectorneutrino physics0103 physical sciencesNeutrino Oscillations. Neutrino detectorsObject DetectionNeutrinoCP: violationDeep Underground Neutrino ExperimentHigh Energy Physics[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]Neutrinos010306 general physicsNeutrino oscillationneutrino/mu: particle identificationIOUScience & TechnologyDUNENeutrino interactions010308 nuclear & particles physicshep-exHigh Energy Physics::PhenomenologyFísicaNeutrino InteractionDetector530 PhysiksensitivityefficiencyHigh Energy Physics::ExperimentElectron neutrino
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640-Slice CT Measurement of Superior Orbital Fissure as Gateway for Light into the Brain: Statistical Evaluation of Area and Distance.

2016

Objective Our aim was to provide normative data concerning superior orbital fissure area (SOFA), ocular skin and the substantia nigra (D-SS) and orbital fissure and the substantia nigra (D-SOF-S) distances by CT scan in adult Caucasian population. Methods The area of the superior orbital fissure (SOF), the distance between the ocular skin and the substantia nigra and the distance between the superior orbital fissure and the substantia nigra using CT and 3D-CT images. Results Normative data stratified for age and gender were obtained. The data here reported show that some degree of variability in SOFA, D-SS and D-SOF-S measurements can be observed healthy Caucasian subjects. Gender stratifie…

Normal Distributionlcsh:MedicineComputed tomographyDistance MeasurementNervous System030218 nuclear medicine & medical imagingDiagnostic RadiologyMidbrain0302 clinical medicineMedicine and Health SciencesMedicineCaucasian populationlcsh:ScienceTomographyMeasurementMultidisciplinaryMovement Disordersmedicine.diagnostic_testNervesOrbital fissureRadiology and ImagingCranial NervesBrainNeurodegenerative DiseasesParkinson DiseaseSubstantia Nigramedicine.anatomical_structureNeurologySuperior orbital fissurePhysical SciencesEngineering and TechnologyAnatomyBrainstemBright lightResearch ArticleImaging TechniquesOcular AnatomySubstantia nigraNeuroimagingResearch and Analysis MethodsMidbrain03 medical and health sciencesDiagnostic MedicineOcular SystemPathologicalbusiness.industrylcsh:RBiology and Life SciencesProbability TheoryProbability DistributionComputed Axial Tomographylcsh:QbusinessNuclear medicine030217 neurology & neurosurgeryMathematicsNeurosciencePloS one
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Observation of the cosmic-ray shadow of the Moon with IceCube

2013

We report on the observation of a significant deficit of cosmic rays from the direction of the Moon with the IceCube detector. The study of this "Moon shadow" is used to characterize the angular resolution and absolute pointing capabilities of the detector. The detection is based on data taken in two periods before the completion of the detector: between April 2008 and May 2009, when IceCube operated in a partial configuration with 40 detector strings deployed in the South Pole ice, and between May 2009 and May 2010 when the detector operated with 59 strings. Using two independent analysis methods, the Moon shadow has been observed to high significance (> 6 sigma) in both detector config…

Nuclear and High Energy PhysicsPhysics::Instrumentation and DetectorsAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesCosmic rayAstrophysics01 natural sciencesNEUTRINO TELESCOPESPosition (vector)SEARCH0103 physical sciencesShadowAngular resolutionddc:530ARRIVAL DIRECTIONS010303 astronomy & astrophysicsDETECTORAnalysis methodHigh Energy Astrophysical Phenomena (astro-ph.HE)PhysicsANISOTROPY010308 nuclear & particles physicsDetectorSUNAstronomyANGULAR RESOLUTIONEarth's magnetic fieldDeflection (physics)Physics and AstronomyAstrophysics - High Energy Astrophysical Phenomena
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Data Blinding for the nEDM Experiment at PSI

2020

Psychological bias towards, or away from, prior measurements or theory predictions is an intrinsic threat to any data analysis. While various methods can be used to try to avoid such a bias, e.g. actively avoiding looking at the result, only data blinding is a traceable and trustworthy method that can circumvent the bias and convince a public audience that there is not even an accidental psychological bias. Data blinding is nowadays a standard practice in particle physics, but it is particularly difficult for experiments searching for the neutron electric dipole moment (nEDM), as several cross measurements, in particular of the magnetic field, create a self-consistent network into which it …

Nuclear and High Energy Physicsdata analysis methodPhysics - Instrumentation and DetectorsOffset (computer science)BlindingNeutron electric dipole momentOther Fields of PhysicsFOS: Physical sciencesSeparate analysis[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]nucl-ex01 natural sciencesHigh Energy Physics - Experimentphysics.data-anHigh Energy Physics - Experiment (hep-ex)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Nuclear Physics - Experiment[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]Nuclear Experiment (nucl-ex)Detectors and Experimental Techniques010306 general physicsNuclear Experimentphysics.ins-detPhysicsn: electric moment010308 nuclear & particles physicshep-exProbability and statisticsInstrumentation and Detectors (physics.ins-det)Data setSpecial Article - New Tools and TechniquesTrustworthinessPhysics - Data Analysis Statistics and ProbabilityAlgorithmData Analysis Statistics and Probability (physics.data-an)Particle Physics - Experiment[PHYS.PHYS.PHYS-DATA-AN]Physics [physics]/Physics [physics]/Data Analysis Statistics and Probability [physics.data-an]
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