Search results for "Anatomia"
showing 10 items of 1108 documents
Rip-1 regulation of caspase expression in PTHrP [38-94]-treated MDA-MB231 breast cancer cells
2004
Rip-1 controlla l’espressione delle caspasi in cellule MDA-MB231 trattate con PTHrP[38-94]-amide
2004
Multi-omics analysis of epithelial-to mesenchymal transition mediators in breast cancer
2022
Effect of cadmium on MDA-MB231 breast cancer cells
2006
We demonstrated that treatment of estrogen receptor-negative (ER-) MDA-MB231 breast cancer cells with 5 M Cd for 96h resulted in an about 50% reduction of cell number
P38 MAPK pathway is involved in cadmium response by MDA-MB231 breast cancer cells
2007
Type V collagen regulates apoptosis-related gene expression in breast cancer cells
2008
Involvement of PKCη in type V collagen-induced apoptosis on 8701-BC breast cancer cells
2007
Breast cancer cell growth/motility is influenced by metal compounds
2019
Triple-negative breast cancer (TNBC) is a highly "aggressive" malignant neoplasm with limited treatment options due to the lack of expression of estrogen and progesterone receptors and HER2/neu. In search of novel molecules displaying anti-TNBC activities, the TNBC cell line MDA-MB231 was exposed to cadmium chloride and/or manganese chloride, and a biological characterization of the effect observed was performed. The data obtained demonstrate a cytotoxic effect exerted by cadmium chloride with drastic changes affecting gene expressions and production of reactive oxygen species. Conversely, manganese chloride was effective in increasing cell number and promoting cell invasive ability. Such e…
Breast cancer proteomics: from research to clinical applications.
2008
The exponentially increasing volume of information extracted from genomic and proteomic applications on cancer, while providing new insights into molecular composition of cancer cells and tissues, imposes new challenges on data rationalization as a tool for clinically relevant biomarker discovery. Breast cancer represents the most frequent and potentially aggressive type of cancer and, moreover, it is one of the most enigmatic and poorly predictable in its evolution, likely because it includes several different forms that behave differently among patients. Current clinical parameters for breast cancer diagnosis and cure are: tumour size, axillary lymph node status, histological grading and …
Mid-region PTHrP and gene expression of MDA-MB231 breast cancer cells
2007
Type V collagen is known to be over-deposited in the stroma of ductal infiltrating carcinomas of the breast. When used as a substrate, type V collagen restrains growth and invasion, and affects gene expression of 8701-BC ductal infiltrating carcinomas cells. Here we supplement existing data by demonstrating type V collagen dependent upregulation of capn2 gene expression in 8701-BC cells through differential display-PCR and Western blot assays. Furthermore, we suggest that our data obtained by centrifugal sedimentation and electrophoresis strongly suggest a correlation between calpain overproduction and DNA fragmentation, since the incubation with calpain inhibitor partly reverts the latter.