Search results for "Arma"

showing 10 items of 14248 documents

New Acyclic Cytotoxic Jasplakinolide Derivative from the Marine Sponge Jaspis splendens

2019

A new acylic jasplakinolide congener (2), another acyclic derivative requiring revision (4), together with two jasplakinolide derivatives including the parent compound jasplakinolide (1) were isolated from the Indonesian marine sponge Jaspis splendens. The chemical structures of the new and known compounds were unambiguously elucidated based on HRESIMS and exhaustive 1D and 2D NMR spectral analysis as well as a comparison of their NMR data with those of jasplakinolide (1). The isolated jasplakinolides inhibited the growth of mouse lymphoma (L5178Y) cells in vitro with IC50 values in the low micromolar to nanomolar range.

0106 biological sciencesStereochemistryPharmaceutical Science01 natural sciencesjasplakinolide Z<sub>5</sub>Drug Discovery<i>Jaspis splendens</i>Ic50 valuesCytotoxic T cellSpectral analysisPharmacology Toxicology and Pharmaceutics (miscellaneous)lcsh:QH301-705.5cytotoxic activitybiology010405 organic chemistryChemistry010604 marine biology & hydrobiologyMouse LymphomaJaspis splendensbiology.organism_classificationIn vitro0104 chemical sciencesSpongelcsh:Biology (General)Two-dimensional nuclear magnetic resonance spectroscopyjasplakinolide Z<sub>6</sub>Marine Drugs
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Stomatal deregulation in Plasmopara viticola-infected grapevine leaves.

2007

International audience; In grapevine, the penetration and sporulation of Plasmopara viticola occur via stomata, suggesting functional relationships between guard cells and the pathogen. This assumption was supported by our first observation that grapevine (Vitis vinifera cv. Marselan) cuttings infected by P. viticola wilted more rapidly than healthy ones when submitted to water starvation. • Here, complementary approaches measuring stomatal conductance and infrared thermographic and microscopic observations were used to investigate stomatal opening/closure in response to infection. • In infected leaves, stomata remained open in darkness and during water stress, leading to increased transpir…

0106 biological sciencesStomatal conductancePLASMOPARA VITICOLAPhysiologySTOMATAL CONDUCTANCEPlant ScienceBiology01 natural sciencesPlant Epidermis03 medical and health scienceschemistry.chemical_compoundABSCISIC ACID (ABA)Guard cellBotanyVitisDOWNY MILDEWAbscisic acid030304 developmental biologyTranspirationOomycete0303 health sciencesfungifood and beveragesWaterbiology.organism_classification[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacySporePlant LeaveschemistryOomycetesGRAPEVINE (VITIS VINIFERA)Plasmopara viticolaGUARD CELLSDowny mildew010606 plant biology & botanyAbscisic AcidThe New phytologistReferences
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Biological films adhering to the oral soft tissues: Structure, composition, and potential impact on taste perception

2018

The role of free-flowing saliva in taste perception is increasingly recognized, but saliva is also present in the mouth as films intimately associated to soft or hard tissues. On mucosal surfaces, particularly on the tongue, the structure and composition of such films (including its microbial constitutive part) may play a particular role in the sense of taste due to their proximity with the taste anatomical structures. This review compiles the current knowledge on the structure of biological films adhering to oral mucosae and on their biochemical and microbiological composition, before presenting possible implications for taste perception. PRACTICAL APPLICATIONS: The understanding of the ro…

0106 biological sciencesTastemedia_common.quotation_subjectAnatomical structuresPharmaceutical ScienceBacterial Physiological Phenomena01 natural sciencestasteOral soft tissues0404 agricultural biotechnologytongueTongue010608 biotechnologyPerceptionmicrobiotamedicineHumansComposition (language)media_commonMouthsalivaPotential impactCommunicationBacteriabusiness.industryMouth MucosaTaste PerceptionEpithelial Cells04 agricultural and veterinary sciencesTaste Buds040401 food sciencemedicine.anatomical_structuremucosal pellicleBiofilmsPsychologybusiness[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood ScienceJournal of Texture Studies
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Guidance for the risk assessment of the presence at low level of genetically modified plant material in imported food and feed under Regulation (EC) …

2017

Abstract This document provides guidance for the risk assessment under Regulation (EC) No 1829/2003 of the unintended, adventitious or technically unavoidable presence in food and feed of low level of genetically modified plant material intended for markets other than in the European Union. In this context, the presence at low level is defined to be maximum 0.9% of genetically modified plant material per ingredient. This guidance is intended to assist applicants by indicating which scientific requirements of Annex II of Regulation (EU) No 503/2013 are considered necessary for the risk assessment of the presence at low levels of genetically modified plant material in food and feed.

0106 biological sciencesVeterinary (miscellaneous)[SDV]Life Sciences [q-bio]Context (language use)Plant ScienceGenetically modified crops010501 environmental sciences01 natural sciencesMicrobiologyRegulation (EU) No 503/2013Ingredientpresence at low level[SDV.IDA]Life Sciences [q-bio]/Food engineeringmedia_common.cataloged_instance[SDV.BV]Life Sciences [q-bio]/Vegetal BiologySettore AGR/18 - Nutrizione E Alimentazione Animale[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringEuropean unionfood/feed0105 earth and related environmental sciencesmedia_commonguidance;GMO;presence at low level;risk assessment;Regulation (EC) No 1829/2003;Regulation (EU) No 503/2013;food/feedbusiness.industryGMORegulation (EC) No 1829/2003risk assessmentguidance; GMO; presence at low level; risk assessment; Regulation (EC) No 1829/2003; Regulation (EU) No 503/2013; food/feed10079 Institute of Veterinary Pharmacology and ToxicologyFood safetyBiotechnologyRegulation (EU) No 503/2013Scientific OpinionSettore AGR/11 - Entomologia Generale E Applicata570 Life sciences; biologyAnimal Science and ZoologyParasitologyRisk assessmentbusinessguidanceRegulation (EC) No 1829/2003010606 plant biology & botanyFood Science
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Male mating success during parturial intermoults in the terrestrial isopod Armadillidium vulgare revealed by the use of a microsatellite locus

2007

3 pages; International audience; We investigated the value of microsatellite DNA markers to improve our knowledge of mating strategy with inference to sperm competition in particular, in the woodlouse Armadillidium vulgare. In terrestrial isopods, mature females develop a brood pouch or marsupium before egg laying, the pouch being formed by overlapping oöstegites during a special moult called parturial moult. Under laboratory conditions, we show that Armadillidium vulgare females are able to mate during parturial intermoults, even in the presence of a physical barrier such as that represented by the ventral marsupial plates. Our results reveal that the contribution of a second male mating w…

0106 biological sciencesWoodlouseZoologyAquatic Science010603 evolutionary biology01 natural sciences03 medical and health sciences[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisSperm competitionComputingMilieux_MISCELLANEOUS030304 developmental biologyMarsupialArmadillidium vulgare0303 health sciences[ SDE.BE ] Environmental Sciences/Biodiversity and EcologybiologyEcology[ SDV.GEN.GA ] Life Sciences [q-bio]/Genetics/Animal geneticsbiology.organism_classificationBrood[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics[ SDV.GEN.GPO ] Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]Pouch[SDE.BE]Environmental Sciences/Biodiversity and EcologyBrood pouchMoulting[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Investigating candidate neuromodulatory systems underlying parasitic manipulation: concepts, limitations and prospects.

2012

Summary Studies addressing the functional basis of parasitic manipulation suggest that alteration of the neuromodulatory system is a common feature of manipulated hosts. Screening of the neuromodulatory system has so far been carried out by performing ethopharmacological analysis, biochemical quantification of neurotransmitters and neuromodulators, and/or immunocytochemistry. Here, we review the advantages and limitations of such approaches through the analysis of case studies. We further address whether the analysis of candidate neuromodulatory systems fits the current view of manipulation as being multidimensional. The benefits in combining ethopharmacology with more recent molecular tool…

0106 biological sciences[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyNeuroimmunomodulationPhysiologyMultidisciplinary studyAquatic ScienceBiology010603 evolutionary biology01 natural sciencesHost-Parasite Interactions03 medical and health sciences[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimalsHumansParasites[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyParasite transmissionMolecular BiologyEcology Evolution Behavior and Systematics030304 developmental biologyethopharmacologyBehavior0303 health sciences[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyneuroethologypsychoneuroimmunologyBiological evolutionBiological EvolutionserotoninInsect Sciencephenotypic engineeringAnimal Science and Zoology[SDE.BE]Environmental Sciences/Biodiversity and EcologyNeurosciencebehavioural manipulation[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Interpreting immunological indices: the importance of taking parasite community into account. An example in blackbirds Turdus merula.

2015

13 pages; International audience; Despite the intensive use of immune indices in immunoecology, whether to interpret the results of immune indices in terms of actual immune competence (i.e. ability to control and clear parasite infections as indicated by high values of immune indices associated with low parasite loads) or current immune activation (pathogenic infection being associated with high parasite load and high values of immune indices) is still an open question. Most studies to date have produced contrasting results focused on the effect of a single parasite species despite the fact that hosts usually harbour a community of parasites that influences one another's impact on host immu…

0106 biological sciences[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitologyanimal diseaseschemical and pharmacologic phenomenaongoing infectionBiologyintestinal parasites010603 evolutionary biology01 natural sciencesParasite load03 medical and health sciencesImmune system[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/Symbiosis[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyParasite hostingParasite Infections[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyBlood parasitesEcology Evolution Behavior and Systematicsimmunoecology030304 developmental biology[ SDE.BE ] Environmental Sciences/Biodiversity and Ecology0303 health sciencesimmunocompetenceEcological ModelingSignificant partbiochemical phenomena metabolism and nutrition3. Good healthbirdsImmunologyparasite communitybacteria[SDV.IMM]Life Sciences [q-bio]/ImmunologyImmunocompetence[SDE.BE]Environmental Sciences/Biodiversity and EcologyImmune activationimmune assay[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Cross-resistance to aryloxyphenoxypropionate and cyclohexanedione herbicides in foxtail millet (Setaria italica)

1997

Abstract Nearly isogenic backcrossed populations of foxtail millet ( Setaria italica (L.) Beauv.), resistant and susceptible to sethoxydim, were used in dose response analysis to seven acetyl-coenzyme A carboxylase inhibiting herbicides, aryloxyphenoxypropionate, and cyclohexanedione. Mortality and fresh and dry weights were recorded at the seedling stage. Results of greenhouse experiments showed that the resistant type was cross-resistant to all tested herbicides. Sethoxydim only was completely safe for the crop while three other herbicides had a moderate effect on the growth of resistant plants at recommended field doses. The last three herbicides had too high a toxicity to be used on mil…

0106 biological sciences[SDE] Environmental SciencesSetariaHealth Toxicology and MutagenesisField experiment[SDV]Life Sciences [q-bio]Population01 natural sciencesBotanyPoaceaeeducationComputingMilieux_MISCELLANEOUSeducation.field_of_studybiologyfood and beverages04 agricultural and veterinary sciencesGeneral Medicinebiology.organism_classificationPhytopharmacology[SDV] Life Sciences [q-bio]HorticultureSeedlingFoxtail[SDE]Environmental Sciences040103 agronomy & agriculture0401 agriculture forestry and fisheriesPhytotoxicityAgronomy and Crop ScienceRESISTANCE GENETIQUE010606 plant biology & botany
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Effects of resveratrol on the ultrastructure of Botrytis cinerea conidia and biological significance in plant/pathogen interactions

2012

International audience; Many roles have been ascribed to stilbenes, namely as antimicrobial, deterrent or repellent compounds in plants, protecting them from attacks by fungi, bacteria, nematodes or herbivores, acting both as constitutive and active defense (phytoalexin) compounds. More recently, stilbenes (especially resveratrol and its derivatives) were acclaimed for their wondrous effects and wide range of purported healing and preventive powers as cardioprotective, antitumor, neuroprotective and antioxidant agents. Although there is a huge number of works concerning the role of resveratrol in human health, reports on the antifungal activity of this compound are still scarce. This study …

0106 biological sciences[SDV]Life Sciences [q-bio]Resveratrol01 natural sciencesConidiumchemistry.chemical_compoundBotrytis cinereaDrug DiscoveryStilbenesDISEASE RESISTANCEVitisPathogenBotrytis cinereachemistry.chemical_classificationELECTRON-MICROSCOPY0303 health sciencesbiologyPhytoalexinfood and beveragesBiological activityGeneral MedicineSpores FungalVITIS-VINIFERA LEAVESAntimicrobialABC TRANSPORTER BCATRB3. Good healthHost-Pathogen Interactions[SDE]Environmental SciencesGrapevineBotrytisSTILBENE PHYTOALEXINSMETABOLISMMicrobiology03 medical and health sciencesPhytoalexinsBotany[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyPLANTSPHYTOALEXIN PHASEOLLINMode of action030304 developmental biologyPlant DiseasesPharmacologyBiological activityfungibiology.organism_classificationchemistryResveratrolGRAPEVINE LEAVESCAUSAL AGENT010606 plant biology & botany
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The Potential Role of Medicinal Mushrooms in the Prevention and Treatment of Gynecological Cancers: A Review

2019

A review of scientific information about the potential role of medicinal mushrooms in the prevention and treatment of gynecological cancers, human immunodeficiency virus, and human papillomavirus infections is reported here. The results of in vivo and in vitro experiments on 16 different species of Basidiomycetes and three Ascomycetes, which possess chemopreventive potential and are effective in clinical application in combination with chemotherapy, are also discussed. Medicinal mushroom extracts confirm an evident efficacy on the reduction of tumor cell proliferation and side effects in patients with gynecological tumors who are undergoing chemotherapy treatments. This review, the first on…

0106 biological sciencesanimal structuresVaginal NeoplasmsGenital Neoplasms Femalemedicine.medical_treatmentHuman immunodeficiency virus (HIV)Uterine Cervical NeoplasmsTumor cellsmedicine.disease_cause01 natural sciencesApplied Microbiology and BiotechnologyAntioxidantsMiceMedicinal mushroomAscomycotaIn vivo010608 biotechnologyDrug DiscoverymedicineAnimalsHumansIn patientHuman papillomavirusPapillomaviridaeCell ProliferationPharmacologyChemotherapyBiological ProductsClinical Trials as Topicbusiness.industryBasidiomycotafungiHIVSettore BIO/03 - Botanica Ambientale E ApplicataCancer researchFemalebusinessAgaricalesmedicinal mushrooms gynecological cancers human immunodeficiency virus human papillomavirus Basidiomycetes Ascomycetes
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