Search results for "Arrow"
showing 10 items of 953 documents
Analysis of the p53 and MDM-2 gene in acute myeloid leukemia
1996
The MDM-2 (murine double minute 2) gene codes for a cellular protein that can bind to the p53 tumor suppressor gene product, thereby functioning as a negative regulator of p53. In order to define the role of the MDM-2 gene in the pathogenesis of human acute myeloid leukemia, the expression and the sequence of the MDM-2 gene were examined in samples of bone marrow and/or peripheral mononuclear cells of 38 patients by using immunostaining, polymerase chain reaction (PCR), single strand conformation polymorphism, and sequencing. Immunohistochemical staining detected a weak accumulation of the MDM-2 protein in AML patients of FAB classification M4 and M5. RT-PCR analysis revealed a heterogeneou…
Tif1gamma Is Essential for Macrophage Differentiation
2011
Abstract Abstract 2370 TIF1gamma (or TRIM33) is an ubiquitous nuclear protein that belongs to the transcriptional intermediary factor 1 family. Human and mouse TIF1gamma are closely related to zebrafish moonshine (mon), a gene whose mutations disrupt embryonic and adult hematopoiesis with severe red blood cell aplasia. Targeted deletion of Tif1gamma is embryonic lethal in mice. In zebrafish and human CD34+ cells, TIF1gamma functionally links positive elongation factors such as p-TEFb and FACT to blood specific transcription complexes (e.g. the SCL/TAL1 complex) to regulate elongation of genes by antagonizing Pol II pausing. TIF1gamma also affects the human hematopoietic progenitor cell resp…
Urban structure changes and environmental factors of Valencian Community towns as potentital drivers of the House Sparrow decline
2021
El gorrión común Passer domesticus (Linnaeus, 1758) se encuentra en declive en gran parte de Europa. En España, destaca el caso de la Comunidad Valenciana, área de estudio de esta tesis, con descensos superiores al 95% en zonas rurales y al 70% en zonas urbanas. Las causas del declive en zonas urbanas no son claras. En los pueblos y ciudades de la Comunidad Valenciana se están produciendo importantes procesos de transformación de la estructura urbana que afectan a la disponibilidad y adecuación del hábitat para la especie. El objetivo de la tesis fue explorar esos cambios como potenciales impulsores del declive del gorrión común. La tesis se distribuye en 8 capítulos. El capítulo 1 contiene…
On the Statistical Properties of Equal Gain Combining over Mobile-to-Mobile Fading Channels in Cooperative Networks
2010
Paper presented at the 2010 IEEE International Conference on Communications (ICC), Cape Town. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works. Paper also available from the publisher: http://dx.doi.org/10.1109/ICC.2010.5501898 This article deals with the statistical analysis of equal gain combining (EGC) over mobile-to-mobile (M2M) fading channels in a dual-hop amplify-and-forward relay network. Here, we…
Mobile-to-mobile fading channels in amplify-and-forward relay systems under line-of-sight conditions: statistical modeling and analysis
2010
Published version of an article from the journal:Annales des Telecommunications/Annals of Telecommunications. The original publication is available at Springerlink. http://dx.doi.org/10.1007/s12243-010-0169-z This paper deals with the modeling and analysis of narrowband mobile-to-mobile (M2M) fading channels for amplify-and-forward relay links under line-of-sight (LOS) conditions. It is assumed that a LOS component exists in the direct link between the source mobile station (SMS) and the destination mobile station (DMS), as well as in the links via the mobile relay (MR). The proposed channel model is referred to as the multiple-LOS second-order scattering (MLSS) channel model. The MLSS chan…
Design and Simulation of Narrowband Indoor Radio Propagation Channels under LOS and NLOS Propagation Conditions
2010
Paper presented at the 2010 IEEE 71st Vehicular Technology Conference. (c) 2010 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works. Paper also available from the publisher: http://dx.doi.org/10.1109/VETECS.2010.5494116 This paper deals with the design and simulation of narrowband indoor propagation channels under line-of-sight (LOS) and non-LOS (NLOS) propagation conditions. We propose a reference cha…
On the Correlation and Ergodic Properties of the Squared Envelope of SOC Rayleigh Fading Channel Simulators
2012
Published version of an article in the journal: Wireless Personal Communications. Also available from the publisher at: http://dx.doi.org/10.1007/s11277-011-0493-2 In this paper, we investigate the correlation and ergodic properties of the squared envelope of a class of autocorrelation-ergodic (AE) sum-of-cisoids (SOC) simulation models for mobile Rayleigh fading channels. Novel closed-form expressions are presented for both the ensemble and the time autocorrelation functions (ACFs) of the SOC simulation model’s squared envelope. These expressions have been derived by assuming that the SOC model’s inphase and quadrature (IQ) components have arbitrary autocorrelation and cross-correlation pr…
Level-crossing rate and average duration of fades of the envelope of mobile-to-mobile fading channels in K-parallel dual-hop relay networks
2009
©2009 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE." Article also available from publisher: http://dx.doi.org/10.1109/WCSP.2009.5371574 This paper studies the fading behavior of narrowband mobile-to-mobile (M2M) fading channels in dual-hop distributed cooperative multi-relay systems under non-line-of-sight (NLOS) propagation conditions. M2M fading channels considered here are associated with amplify-and-forward …
The Riemann sum method for the design of sum-of-cisoids simulators for Rayleigh fading channels in non-isotropic scattering environments
2009
©2009 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE. Article also available from publisher: http://dx.doi.org/10.1109/ICUMT.2009.5345371 In this paper, we introduce the Riemann sum method (RSM) as an effective tool for the design of sum-of-cisoids (SOC) simulators for narrowband mobile Rayleigh fading channels under non-isotropic scattering conditions. We show that the RSM results in an excellent approximation of…
Endothelial progenitor cells: Are they displaying a function in autoimmune disorders?
2016
Endothelial Progenitor Cells (EPCs) are bone marrow derived cells able to differentiate in mature endothelial cells (EC) contributing to the generation of new vessels, connecting to fibronectin, and forming colonies and/or colony forming units. Since circulating EPCs can be actively considered part of endothelial damage in several cardiovascular diseases and autoimmune disorders the possibility to have a measure for endothelium damage should be considered of interest to predict the patient out-come. At the same time the EPCs proliferative and regenerative role could be considered for therapeutic applications. Studies have been performed to elucidate the role of EPCs in Systemic Sclerosis an…