Search results for "Association."
showing 10 items of 1723 documents
A cultural comparison of mindfulness and student performance: Evidence from university students in five countries
2021
Societal and cultural norms are important in shaping how individuals live, study, and work. Of particular interest in recent research is the role of mindfulness, defined as the ability to focus on the present moment, and how it can impact cognitive function and productivity. This study examines the relationship between scholastic achievement and mindfulness among university students in China, Finland, Germany, South Africa, and the United States. Comparisons between countries with respect to self-reported measures of mindfulness, test anxiety levels, and phone usage are analyzed. These measures are used to determine whether mindfulness affects student performance in introductory economics c…
Executive function and life-space mobility in old age
2018
Life-space assessment incorporates all movements in terms of the distance from home, the frequency of movement and the need of assistance for movement. Executive function (EF) is an important higher order cognitive ability that controls and guides people’s goal-directed actions. We examined the cross-sectional and longitudinal associations between EF and life-space mobility, and investigated if perceived walking difficulties, lower extremity performance, and transportation difficulties explain the association. Methods 157 community-dwelling persons aged 76–91 years participated in the study at the baseline, and 103 of them in 2-year follow-up study. Based on the distribution on the Trail Ma…
Do mobility, cognitive functioning, and depressive symptoms mediate the association between social activity and mortality risk among older men and wo…
2013
Social activity and health correlate in old age, but less is known about what explains this association. The aim of this study was to investigate whether mobility, cognitive functioning, and depressive symptoms mediate the association between social activity and mortality risk, or whether they alternatively should be considered as prerequisites for social activity in older Finnish men and women. In 1988, 406 men and 775 women aged 65–84 years took part in face-to-face interviews about their health, socioeconomic status, and social activities. Confirmatory factor analyses were used to form latent variables describing collective and productive social activity. Latent variable models were used…
Genome-Wide Inhibition of Pro-atherogenic Gene Expression by Multi-STAT Targeting Compounds as a Novel Treatment Strategy of CVDs.
2018
Cardiovascular diseases (CVDs), including atherosclerosis, are globally the leading cause of death. Key factors contributing to onset and progression of atherosclerosis include the pro-inflammatory cytokines Interferon (IFN)a and IFN? and the Pattern Recognition Receptor (PRR) Toll-like receptor 4 (TLR4). Together, they trigger activation of Signal Transducer and Activator of Transcription (STAT)s. Searches for compounds targeting the pTyr-SH2 interaction area of STAT3, yielded many small molecules, including STATTIC and STX-0119. However, many of these inhibitors do not seem STAT3-specific. We hypothesized that multi-STAT-inhibitors that simultaneously block STAT1, STAT2, and STAT3 activit…
A web-based collection of genotype-phenotype associations in hereditary recurrent fevers from the Eurofever registry
2017
PubMed ID: 29047407
cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel
2020
Abstract Background Resistance to enteric pathogens is a complex trait at the crossroads of multiple biological processes. We have previously shown in the Drosophila Genetic Reference Panel (DGRP) that resistance to infection is highly heritable, but our understanding of how the effects of genetic variants affect different molecular mechanisms to determine gut immunocompetence is still limited. Results To address this, we perform a systems genetics analysis of the gut transcriptomes from 38 DGRP lines that were orally infected with Pseudomonas entomophila. We identify a large number of condition-specific, expression quantitative trait loci (local-eQTLs) with infection-specific ones located …
Survey of Italian Pediatricians on awareness, experiences and beliefs regarding direct-to-consumer genetic testing in minors
2022

 Background: Our study wanted to assess Italian pediatricians’ awareness, experience and beliefs regarding directto-consumer (DTC) genetic tests (GT) in minors, with a focus on those for predisposition to complex disease, lyfestyle, athletic ability and other inborn talents.
 Methods: A 28-item questionnaire was administered through the SurveyMonkey® web platform to the 9,086 members of the Italian Society of Pediatrics for which a valid email address was available. The survey was opened from April through November 2017. Statistical analyses were performed using the Graphpad software package.
 Results: 36.2% of the 442 respondents were aware of DTC-GT, but only 23.1% of them…
A Preliminary Analysis of the Importance of Distance, Angle, and Insight When Soccer Referees Make Penalty Decisions
2021
Soccer referees move freely on the pitch to place themselves in the best location for making decisions. While Football Association UK (FA) highlights that a referee should never be more than 20 m away from the playing situation, previous studies have been inconsistent in indicating appropriate distance to a situation for increasing the likelihood of a correct decision. Further, appropriate angle and insight are also likely to influence the correctness of referees' decisions. The aim of this study was to provide an initial investigation of elite referees' positioning in the field (distance, angle, and insight) when making correct and erroneous decisions in potential penalty situations. An ex…
Semantic processing in children with autism spectrum disorder
2021
El presente estudio analizó el procesamiento semántico de un grupo de niños con trastorno del espectro autista (n= 24), con el objetivo principal de averiguar si presentan diferencias en comparación con un grupo de niños con desarrollo típico (n = 24). Para ello, se realizó un análisis del contenido de los ítems del subtest de información del WPPSY-III, estableciendo una serie de categorías en función del tipo de demanda semántica requerida: asociación significante-significado, relación experiencial y conocimiento general. Los resultados obtenidos apoyan la idea de que los niños con autismo realizarían un procesamiento semántico de la información de la misma manera que los niños sin autismo…
Sport as a channel for cultural identity - an examination ofamateur and professional activities : a case study of the Gaelic Athletic Association (GA…
2011
Gaelic Athletic Association (GAA) sports are under the threat of global and more commercially viable sports. This thesis examines the relationship between the GAA and the communities it is involved with. The research has shown a research gap relating to the significance of the GAA in the lives of Irish people, while also examining this organisation through amateur and professional perspectives throughout this research. The impact of this study is of a significant importance in the relationship that exists between Irish people and the GAA. The main research task evaluates the relationship between the GAA as an organisation and the people who participate in the sports. The method of research …