Search results for "Athen"
showing 10 items of 59 documents
Frailty syndrome is associated with changes in peripheral inflammatory markers in prostate cancer patients undergoing androgen deprivation therapy.
2019
To evaluate the role of peripheral inflammation (leukocyte differential count, the proinflammatory cytokines IL-beta, TNF-α, IL-6, IL-8, and the inflammatory markers fibrinogen and C-reactive protein [CRP]) in frailty syndrome in patients with prostate cancer (CaP) undergoing antiandrogen therapy (ADT).A total of 46 men between 51 and 92 years of age with CaP and receiving ADT were classified as frail, prefrail or robust according to the Fried scale. A geriatric assessment was performed, based on the Minimental State Examination for cognitive function, the Barthel index for basic activities of daily living, the Yesavage scale for geriatric depression, and the Athens insomnia scale. In addit…
Brief an Garlieb H. Merkel
1799
Ms. 930a, Nr. 8, Bl. 22r-23v Böttiger, Karl August. Brief an Garlieb H. Merkel, Weimar, d[en] 13. November 1797 Autora rokraksts / Autograph, vācu, angļu un latīņu val. / Deutsch, Englisch und Latein [4] lpp. / S. Attēlu numuri / Bildnummern: 930a-008-1 – 930a-008-4 Der Verfasser nennt in diesem inhaltsreichen Brief zahlreiche Namen und hält nicht nur die Verbindung mit Merkel, die aus dessen erstem Aufenthalt in Weimar resultierte, aufrecht, sondern gibt ihm weitere Hinweise und Empfehlung für seinen weiteren Aufenthalt in Dänemark. So rät er zur Übersetzung dreier Romane aus dem Englischen, darunter Jane Wests „A gossip's story“ (London 1796). Ferner bittet der Verfasser Merkel um Gefälli…
Sicilia e Grecia La conservazione dei monumenti alla fine del Settecento
2015
Fin dalla seconda metà del Settecento in Sicilia si inizia a tutelare, e dunque conservare, i monumenti dell’epoca classica della città di Taormina e perfino un gruppo di alberi secolari, chiamati il “castagno dei cento cavalli”. Inoltre, nel 1778, il governo borbonico istituì, per tutti i monumenti antichi della Sicilia, una commissione formata dai “Regi custodi” – sopraintendenti delle antichità, da un architetto esperto di monumenti antichi, da un pittore di vedute e da un capo mastro, per studiare e rilevare lo stato di conservazione dei monumenti stessi. A seguito di queste indagini, nel 1780, furono approntati i primi interventi di restauro nel tempio di Segesta e in alcuni templi di …
Surface investigation and aluminum oxide estimation on test filters for the ATHENA X-IFU and WFI detectors
2016
The ATHENA mission provides the demanded capabilities to address the ESA science theme "Hot and Energetic Universe". Two complementary instruments are foreseen: the X-IFU (X-ray Integral Field Unit) and WFI (Wide Field Imager). Both the instruments require filters to avoid that the IR radiation heats the X-IFU cryogenic detector and to protect the WFI detector from UV photons. Previous experience on XMM filters recommends to employ bilayer membrane consisting of aluminum deposited on polyimide. In this work, we use the X-ray Photoelectron Spectroscopy (XPS) to quantify the native aluminum oxide thickness that affects the spectral properties of the filter. The estimation of the oxide thickne…
Preliminary Mechanical Characterization of Thermal Filters for the X-IFU Instrument on Athena
2018
The X-ray Integral Field Unit (X-IFU) is one of the two instruments of the Athena astrophysics space mission approved by ESA in the Cosmic Vision Science Program. The X-IFU consists of a large array of TES microcalorimeters that will operate at ~ 50 mK inside a sophisticated cryostat. A set of thin filters, highly transparent to X-rays, will be mounted on the cryostat thermal shields in order to attenuate the IR radiative load, to attenuate RF electromagnetic interferences, and to protect the detector from contamination. In this paper, we present the current thermal filters design, describe the filter samples developed/procured so far, and present preliminary results from the ongoing charac…
The x-ray microcalorimeter spectrometer onboard Athena
2012
Trabajo presentado a la conferencia: "Space Telescopes and Instrumentation: Ultraviolet to Gamma Ray" celebrada en Amsterdam (Holanda) el 1 de julio de 2012.-- et al.
Development of the wide field imager for Athena
2015
The WFI (Wide Field Imager) instrument is planned to be one of two complementary focal plane cameras on ESA's next X-ray observatory Athena. It combines unprecedented survey power through its large field of view of 40 arcmin x 40 arcmin together with excellent count-rate capability (>= 1 Crab). The energy resolution of the silicon sensor is state-of-the-art in the energy band of interest from 0.2 keV to 15 keV, e.g. the full width at half maximum of a line at 6 keV will be <= 150 eV until the end of the nominal mission phase. This performance is accomplished by using DEPFET active pixel sensors with a pixel size of 130 μm x 130 μm well suited to the on-axis angular resolution of 5 arcsec of…
Preliminary assessment of the ATHENA/WFI non-X-ray background
2017
We present a preliminary assessment of the non-X-ray background for the WFI on board ATHENA conducted at IAAT in the context of the collaborative background and radiation damage working group activities. Our main result is that in the baseline configuration originally assumed for the camera the requirement on the level of non-X-ray background could not be met. In light of the results of Geant4 simulations we propose and discuss a possible optimization of the camera design and pinpoint some open issues to be addressed in the next phase of investigation. One of these concerns the possible contribution to the non-X-ray background from soft protons and ions funneled to the focal plane through t…
The filter wheel and filters development for the X-IFU instruments onboard Athena
2016
Athena is the large mission selected by ESA in 2013 to investigate the science theme “Hot and Energetic Universe” and presently scheduled for launch in 2028. One of the two instruments located at the focus of the 12 m-long Athena telescope is the X-ray Integral Field Unit (X-IFU). This is an array of TES microcalorimeters that will be operated at temperatures of 50 mK in order to perform high resolution spectroscopy with an energy resolution down to 2.5 eV at energies < 7 keV. In order to cope with the large dynamical range of X-ray fluxes spanned by the celestial objects Athena will be observing, the X-IFU will be equipped with a filter wheel. This will allow the user to fine tune the i…
The optical blocking filter for the ATHENA wide field imager: Ongoing activities towards the conceptual design
2015
ATHENA is the L2 mission selected by ESA to pursue the science theme "Hot and Energetic Universe" (launch scheduled in 2028). One of the key instruments of ATHENA is the Wide Field Imager (WFI) which will provide imaging in the 0.1-15 keV band over a 40'x40' large field of view, together with spectrally and time-resolved photon counting. The WFI camera, based on arrays of DEPFET active pixel sensors, is also sensitive to UV/Vis photons. Optically generated electron-hole pairs may degrade the spectral resolution as well as change the energy scale by introducing a signal offset. For this reason, the use of an X-ray transparent optical blocking filter is needed to allow the observation of all …