Search results for "Atopic"
showing 10 items of 100 documents
Skimager for the objective erythema estimation in atopic dogs
2020
In this study, the severity of canine skin erythema was assessed objectively for the first time. Atopic dermatitis (AD) is a common canine inflammatory and pruritic skin disease associated with an allergic reaction to exogenous allergens. The monitoring of skin erythema over time with lesion severity scales like the CADESI-4 is an essential diagnostic and research tool, especially for clinical trials. Currently, the erythema assessment is subjective due to visual estimation. In our study, we calculated the erythema index (EI) in 14 atopic dogs based on the analysis of multispectral skin images taken with the Skimager device. The relationship between the EI and a visual erythema estimation w…
Comparison of Epidermal Barrier Integrity in Adults with Classic Atopic Dermatitis, Atopic Prurigo and Non-Atopic Prurigo Nodularis
2021
Simple Summary Atopic dermatitis, also called neurodermatitis, is one of the best-known chronic inflammatory skin diseases with eczema, strong itch and dry skin. It is based on an impaired skin barrier with changes in the fats and proteins of the horny layer, which leads to a disturbed water balance. Prurigo nodularis is a less common and intractable chronic skin disease with very itchy nodules. It can be associated with atopic dermatitis (so called atopic prurigo) or with many other diseases. The aim of this study was to compare these three skin diseases classic atopic dermatitis, atopic prurigo and non-atopic prurigo nodularis with healthy control subjects with regard to their skin barrie…
Estudio contrastivo lingüístico y semántico de las construcciones verbales fijas diatópicas mexicanas/españolas
2010
En este artículo analizamos las construcciones verbales fijas de origen mexicano, y las compararemos con construcciones homólogas del español peninsular desde el punto de vista lingüístico y semántico con el fin de poner de relieve las peculiaridades de estas variantes diatópicas. In the present paper, we analyse set verbal constructions of Mexican origin and compare them with homologous verbal constructions of European Spanish origin from a morphological and semantic point of view in order to underline the peculiarities of the Mexican, diatopic varieties.
Adipokines as Biomarkers of Atopic Dermatitis in Adults
2020
Atopic dermatitis (AD) is characterized by chronic, relapsing, pruritic skin inflammation and does not have a well-understood pathogenesis. In this study, we addressed the contribution of adipokines to AD eczema based on the assessment of blood levels of adiponectin, resistin, leptin, lipocalin-2, and vaspin in adult non-obese patients suffering from chronic extrinsic childhood-onset AD. We investigated 49 AD patients with a median age of 37 years. The control group consisted of 30 age-matched healthy subjects. Adipokines were assessed in the serum by ELISA assays and the severity of AD with the SCORing Atopic Dermatitis (SCORAD) index. We found that adiponectin and resistin decreased and l…
VITAMINA D, ALLERGIE ED ASMA
2013
Comparing tacrolimus ointment and oral cyclosporine in adult patients affected by atopic dermatitis: a randomized study
2004
BACKGROUND: Atopic dermatitis (AD) is a chronic allergic inflammatory disease, which manifests itself with eczematous skin lesions. OBJECTIVE: We compared the clinical efficacy of tacrolimus ointment (0.1%) given twice a day and oral cyclosporine (3 mg/kg) given once daily. Rescue medication for itching included cetirizine 10-20 mg (equal to one or two tables). METHODS: Thirty patients, aged 13-45 years (mean+/-SD 27.1+/-10.9), with a history of moderate-to-severe AD were randomized to treatments, 15 patients for each treatments. Assessment of efficacy was based on SCORAD, on scores of daily itching, erythema, interference with sleep, due to the skin condition and days without use of cetiri…
Probiotics in the prevention and treatment of atopic dermatitis
2020
The use of probiotic supplements might change the composition of the intestinal flora of children, subsequently modulating the immune system's reactivity. The effects of probiotic administration for the prevention/treatment of allergic diseases and atopic dermatitis, in particular, are still so controversial that no definitive recommendation can be made at this stage. Differences in strain specificity, timing, and length of administration all contribute to diversifying the conclusions of this review.
Probiotiku izvēle atopiskā dermatīta gadījumos
2018
Alerģijas epidēmijas veicināšanā lielu lomu spēlē mūsdienu attīstītās sabiedrības dzīvesveids, kuru raksturo mikrobiālas floras nomākšana, tā izmainot cilvēka mikrobiotu un negatīvi ietekmējot imūno regulāciju (Fiocchi et al 2015). Maģistra darba mērķis bija noskaidrot dermatologu viedokli par atopisko dermatītu, ņemot vērā ārstēšanas vadlīnijas, un, izanalizējot zinātniskās publikācijas, izpētīt atopiskā dermatīta ārstēšanas tendences Latvijā, un izpētīt probiotiķu lomu atopiskā dermatīta profilaksē. Anketas aizpildīja ārsti – dermatologi (praktizējošie ārsti). Datu analīzei tika izmantotas 70 aptaujas. Secinājumi: Atopiskā dermatīta ārstēšanā visbiežāk izvēlas topiski lietojamos glokokort…
Vitamin D, allergies and asthma: focus on pediatric patients
2014
In recent years, the interest of the scientific world towards vitamin D gradually increased, and several studies have been conducted to dissect its possible role in modulating the development/course of allergic diseases. Also, Vitamin D supplementation has been assessed as a beneficial approach for treating allergies in some, but not all studies. We reviewed herein the available and relevant literature concerning the possible links between Vitamin D, its supplementation and allergic diseases. A literature search was made independently by the Authors, identifying articles for a narrative review. As per literature, Vitamin D plays a key role in calcium and phosphate metabolism, and it is esse…
Current management of atopic dermatitis and interruption of the atopic march.
2003
Treatment of atopic dermatitis requires a comprehensive approach that includes evaluation of potential triggers and education of the patient and family regarding proper avoidance measures. Hydration of the skin and maintenance of an intact skin barrier remain integral to proper management. Although topical corticosteroids have been a mainstay of anti-inflammatory therapy, the newer topical calcineurin inhibitors offer advantages for treatment of this chronic, relapsing disease. Studies aimed at defining optimal combination therapy and early intervention might change the treatment paradigm for atopic dermatitis.