Search results for "Auditory"
showing 10 items of 568 documents
Immunfluorescence study of neuropeptides in identified neurons of the rat auditory superior olivary complex.
1999
The present study was conducted to investigate the distribution and immunohistochemical characteristics of ascending and descending projection neurons of the rat superior olivary complex (SOC), a group of interrelated brainstem nuclei. Ascending neurons were identified by injection of cholera toxin B subunit (CTB) into the central nucleus of the inferior colliculus (IC), descending neurons were labeled by application of Fluoro-Gold (FG) into the scala tympani of the cochlea, ipsilaterally to the IC injection. In accordance with the literature, we observed neurons innervating the IC located in the lateral superior olivary nucleus (LSO) and dorsal periolivary groups (DPO) on both sides, in th…
The keyboard as a part of visual, auditory and kinesthetic processing in sight-reading at the piano
2009
Sight-reading at the piano requires coordination of multiple modalities—visual, auditory, and kinesthetic. Visual feedback (obtained by looking at the keyboard and the fingers) is usually regarded as one means by which pianists guide musical performance, but few researchers have focused on the organisational aspects implicit in the information provided by the keyboard. This study investigated the role of the keyboard with respect to the visual, auditory, and kinesthetic modalities involved in sight-reading. Five pianists sight-read two compositions, each in a different musical style. They were then interviewed in a semi-structured interview format. A qualitative content analysis was made fr…
Acoustic rendering of particle-based simulation of liquids in motion
2009
In interaction and interface design, the representation of continuous processes often uses liquid metaphors, such as dripping or streaming. When an auditory display of such processes is required, an approach to sound-synthesis based on the physics of liquids in motion would be the most convincing, especially when real-time interaction is into play. In order to bridge the complexity of fluid-dynamic simulations with the needs of interactive sonification, we propose a multi-rate sound synthesis of liquid phenomena. Low-rate smoothed-particle hydrodynamics is used to model liquids in motion and to trigger sound-emitting events. Such events, such as solid-liquid collision, or bubble formation, …
Modeling Listeners’ Emotional Response to Music
2012
An overview of the computational prediction of emotional responses to music is presented. Communication of emotions by music has received a great deal of attention during the last years and a large number of empirical studies have described the role of individual features (tempo, mode, articulation, timbre) in predicting the emotions suggested or invoked by the music. However, unlike the present work, relatively few studies have attempted to model continua of expressed emotions using a variety of musical features from audio-based representations in a correlation design. The construction of the computational model is divided into four separate phases, with a different focus for evaluation. T…
Are we "experienced listeners"? A review of the musical capacities that do not depend on formal musical training.
2006
The present paper reviews a set of studies designed to investigate different aspects of the capacity for processing Western music. This includes perceiving the relationships between a theme and its variations, perceiving musical tensions and relaxations, generating musical expectancies, integrating local structures in large-scale structures, learning new compositional systems and responding to music in an emotional (affective) way. The main focus of these studies was to evaluate the influence of intensive musical training on these capacities. The overall set of data highlights that some musical capacities are acquired through exposure to music without the help of explicit training. These ca…
Hearing among 75-year-old people in three Nordic localities: A comparative study
2005
The aim of this study was to compare auditory functions and to analyse the prevalence of hearing impairment and the relationship of self-reported hearing disability with audiometric test results among 75-year-old people in three Nordic localities. The representative samples came from Glostrup, Denmark (n = 571), Goteborg, Sweden (n =450), and Jyvaskyla, Finland (n =388). The median pure-tone thresholds were rather similar in all three populations. The prevalence of moderate hearing impairment varied between 26% and 34% in men, and between 17% and 23% in women. The corresponding figures in the prevalence of self-reported hearing difficulties were 41%-57%, and 28%-37%. The self-reported diffi…
Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complex
2000
International audience; Defects in myosin VIIA are responsible for deafness in the human and mouse. The role of this unconventional myosin in the sensory hair cells of the inner ear is not yet understood. Here we show that the C-terminal FERM domain of myosin VIIA binds to a novel transmembrane protein, vezatin, which we identi®ed by a yeast two-hybrid screen. Vezatin is a ubiquitous protein of adherens cell±cell junctions, where it interacts with both myosin VIIA and the cadherin±catenins complex. Its recruitment to adherens junctions implicates the C-terminal region of a-catenin. Taken together, these data suggest that myosin VIIA, anchored by vezatin to the cadherin±catenins complex, cre…
CNTN6 mutations are risk factors for abnormal auditory sensory perception in autism spectrum disorders
2017
International audience; Contactin genes CNTN5 and CNTN6 code for neuronal cell adhesion molecules that promote neurite outgrowth in sensory-motor neuronal pathways. Mutations of CNTN5 and CNTN6 have previously been reported in individuals with autism spectrum disorders (ASDs), but very little is known on their prevalence and clinical impact. In this study, we identified CNTN5 and CNTN6 deleterious variants in individuals with ASD. Among the carriers, a girl with ASD and attention-deficit/hyperactivity disorder was carrying five copies of CNTN5. For CNTN6, both deletions (6/1534 ASD vs 1/8936 controls; P=0.00006) and private coding sequence variants (18/501 ASD vs 535/33480 controls; P=0.000…
Histochemical localization of calcium ATPase in the cochlea of the guinea pig
1992
The activity of Ca(2+)-ATPase in the inner ear of the guinea pig was studied ultracytochemically by the lead citrate reaction. The electron-dense reaction products as an expression of Ca(2+)-ATPase activity were localized in endolymphatic cells of Reissner's membrane, in outer and inner hair cells and in some supporting cells. The main finding was the difference in the localization of Ca(2+)-ATPase in outer and inner hair cells. In the latter cells the activity sites were mainly intracellular and in apical membrane specializations, whereas in the outer hair cells the enzyme was localized in the apical membrane specializations and the basolateral plasma membrane.
Does tinnitus distress depend on age of onset?
2011
Objectives: Tinnitus is the perception of a sound in the absence of any physical source of it. About 5–15% of the population report hearing such a tinnitus and about 1–2% suffer from their tinnitus leading to anxiety, sleep disorders or depression. It is currently not completely understood why some people feel distressed by their tinnitus, while others don’t. Several studiesindicate that the amount of tinnitus distress is associated with many factors including comorbid anxiety, comorbid depression, personality, the psychosocial situation, the amount of the related hearing loss and the loudness of the tinnitus.Furthermore, theoretical considerations suggest an impact of the age at tinnitus o…