Search results for "BASAL"
showing 10 items of 920 documents
Model to Assess the Quality of Magmatic Rocks for Reliable and Sustainable Constructions
2017
Geomechanical assessment of rocks requires knowledge of phenomena that occur under the influence of internal and external factors at a macroscopic or microscopic scale, when rocks are submitted to different actions. To elucidate the quantitative and qualitative geomechanical behavior of rocks, knowing their geological and physical–mechanical characteristics becomes an imperative. Mineralogical, petrographical and chemical analyses provided an opportunity to identify 15 types of igneous rocks (gabbro, diabases, granites, diorites, rhyolites, andesites, and basalts), divided into plutonic and volcanic rocks. In turn, these have been grouped into acidic, neutral (intermediate) and basic magmat…
Basaltic Rocks Analyzed by the Spirit Rover in Gusev Crater
2004
The Spirit landing site in Gusev Crater on Mars contains dark, fine-grained, vesicular rocks interpreted as lavas. Pancam and MiniâThermal Emission Spectrometer (Mini-TES) spectra suggest that all of these rocks are similar but have variable coatings and dust mantles. Magnified images of brushed and abraded rock surfaces show alteration rinds and veins. Rock interiors contain â¤25% megacrysts. Chemical analyses of rocks by the Alpha Particle X-ray Spectrometer are consistent with picritic basalts, containing normative olivine, pyroxenes, plagioclase, and accessory FeTi oxides. MoÌssbauer, Pancam, and Mini-TES spectra confirm the presence of olivine, magnetite, and probably pyroxene. The…
Critical phenomena originating magmatic rocks in western Sicily.
1984
The behaviour of a model magma in the vicinity of a critical region is in agreement with results of studies of structures in the melt in basaltic rocks from Sicily. The behaviour of ionic-non ionic fluid mixtures simulating a magma has been analysed in the light of results obtained recently with simple statistical mechanical approximations. It is suggested that the Sicilian magma is to be considered as an extremely rare natural example of two immiscible liquids having almost consolute composition.
Neuroendocrine indicators of allostatic load reveal the impact of environmental acidification in fish
2020
Abstract When mobilized from surrounding soils and binding to gills at moderately low pH, aluminum (Al) cations can adversely affect fish populations. Furthermore, acidification may lead to allostatic overload, a situation in which the costs of coping with chronic stress affects long-term survival and reproductive output and, ultimately, ecosystem health. The brain's serotonergic system plays a key role in neuroendocrine stress responses and allostatic processes. Here, we explored whether sublethal effects of Al in acidified water affects serotonergic neurochemistry and stress coping ability in a unique land-locked salmon population from Lake Bygelandsfjorden, in southern Norway. Fish were …
Constraints on the Cretaceous thermal event in the Transantarctic Mountains from alteration processes in Ferrar flood basalts
1999
Abstract K–Ar and 40 Ar/ 39 Ar incremental-heating analyses on apophyllite formed during hydrothermal alteration of volcanic rocks from the Ferrar Supergroup in North Victoria Land, Antarctica, provide strong evidence for hydrothermal events during mid-Cretaceous time. A last event has been dated at 96.7±0.6 Ma. Variable older ages between 112 and 125 Ma are interpreted as mixed ages of hydrothermal events or may be caused by disturbances of the Ar–Ar system. The Rb–Sr isotope system of the apophyllites is not applicable to dating because a large portion of the Sr is radiogenic and because of Rb-mobility in the crystal structure. Secondary mineralogy suggests a temperature for alteration be…
Long-Term Behavioral Programming Induced by Peripuberty Stress in Rats Is Accompanied by GABAergic-Related Alterations in the Amygdala
2014
Stress during childhood and adolescence is a risk factor for psychopathology. Alterations in γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the brain, have been found following stress exposure and fear experiences and are often implicated in anxiety and mood disorders. Abnormal amygdala functioning has also been detected following stress exposure and is also implicated in anxiety and social disorders. However, the amygdala is not a unitary structure; it includes several nuclei with different functions and little is known on the potential differences the impact of early life stress may have on this system within different amygdaloid nuclei. We aimed here to evaluate pote…
Utilidad de Bcl-2 como nuevo marcador de expresión de células basales en patología prostática
2006
Resumen Introduccion y objetivos El diagnostico de adenocarcinoma invasor de prostata es con frecuencia dificil en biopsias cilindricas, siendo fundamental en estos casos la determinacion de la presencia de celulas basales. en la actualidad, la expresion inmunohistoquimica del antigeno 34betae12 junto con la proteina p63 son los marcadores mas utilizados. en nuestro estudio, se analizo comparativamente la expresion de 34betae12, p63, bcl-2 y alfa-metilacil-coa racemasa para valorar la utilidad de bcl-2 como nuevo marcador de celulas basales en patologia prostatica. Metodos y resultados El estudio incluia piezas de prostatectomia de 48 pacientes en los que se analizo la ausencia de marcaje i…
Adenocarcinoma de células basales del saco lacrimal bien diferenciado. A propósito de un caso
2007
El adenocarcinoma de celulas basales es un tumor raro y descrito por la Organizacion Mundial de la Salud (OMS) en 1991 como entidad propia. La edad media de presentacion es de 48 anos y no muestra predominio sexual. El curso es insidioso con signos y sintomas inespecificos. Presentamos un caso de adenocarcinoma de saco lacrimal, cuyo diagnostico se realizo por anatomia patologica. Mostramos los hallazgos de tomografia computarizada, resonancia magnetica y anatomia patologica. Se comenta el diagnostico diferencial y el tratamiento.
Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells…
2008
International audience; Purpose: To characterize the possible cytotoxic effects of oxysterols (7-hydroxycholesterol (7-OH), 25-hydroxycholesterol (25-OH)) in human retinal pigment epithelial cells (ARPE-19) and to detail the relationships between some of these effects. Methods: ARPE-19 cells were treated with 7-OH and 25-OH. Cell viability was measured with the MTT assay. Membrane permeability, mitochondrial potential, and lysosomal integrity were measured by flow cytometry with propidium iodide, DiOC6(3), and acridine orange, respectively. Cell death was characterized by staining with Hoechst 33342, transmission electron microscopy, and analysis of the DNA fragmentation pattern. Caspase ac…
Sonidegib en el tratamiento del carcinoma basocelular localmente avanzado
2021
Resumen: Sonidegib es un inhibidor del receptor transmembrana Smoothened (SMO), de la vía de señalización de Hedgehog, indicado para el tratamiento del carcinoma basocelular localmente avanzado (CBCla), no susceptible a cirugía curativa ni a radioterapia. Sonidegib ha demostrado su eficacia y seguridad en pacientes con CBCla en el ensayo de fase II (BOLT), donde el 61% (IC 95%: 48; 72) de los pacientes tratados con 200 mg de sonidegib tuvo una respuesta objetiva al tratamiento, con un tiempo medio hasta la respuesta de cuatro meses. La mediana de duración de respuesta fue de 26,1 meses y la mediana de supervivencia libre de progresión fue de 22,1 meses. Los eventos adversos más frecuentes f…