Search results for "BM"
showing 10 items of 1459 documents
The hematopoietic niche: a Drosophila model, at last.
2007
The niche provides a specialised microenvironment necessary for maintenance of stem cells in a non differentiated state. While the hematopoietic stem cell (HSC) niche in vertebrates was the first to be recognized, Drosophila niches supporting germline stem cells were characterised first. Recent evidence for the existence of a niche maintaining hematopoietic precursors in Drosophila opens the way to study in vivo the niche/hematopoietic precursors interactions. The availability of a large collection of cell markers, mutants and sophisticated genetic tools makes Drosophila an attractive model for investigating the cellular and molecular mechanisms that are involved in these interactions.
SILAC labeling coupled to shotgun proteomics analysis of membrane proteins of liver stem/hepatocyte allows to candidate the inhibition of TGF-beta pa…
2014
Background: Despite extensive research on hepatic cells precursors and their differentiated states, much remains to be learned about the mechanism underlying the self-renewal and differentiation.Results: We apply the SILAC (stable isotope labeling by amino acids in cell culture) approach to quantitatively compare the membrane proteome of the resident liver stem cells (RLSCs) and their progeny spontaneously differentiated into epithelial/hepatocyte (RLSCdH). By means of nanoLC-MALDI-TOF/TOF approach, we identified and quantified 248 membrane proteins and 57 of them were found modulated during hepatocyte differentiation. Functional clustering of differentially expressed proteins by Ingenuity …
VLTI/AMBER spectro-interferometry of the late-type supergiants V766 Cen (=HR 5171 A), σ Oph, BM Sco, and HD 206859
2017
Aims. We add four warmer late-type supergiants to our previous spectro-interferometric studies of red giants and supergiants. Methods. We measure the near-continuum angular diameter, derive fundamental parameters, discuss the evolutionary stage, and study extended atmospheric atomic and molecular layers. Results. V766 Cen (=HR 5171 A) is found to be a high-luminosity (log L/L = 5.8 ± 0.4) source of effective temperature 4290 ± 760 K and radius 1490 ± 540 R, located in the Hertzsprung-Russell (HR) diagram close to both the Hayashi limit and Eddington limit; this source is consistent with a 40 M evolutionary track without rotation and current mass 27-36 M. V766 Cen exhibits Na i in emission a…
Prehibernation and hibernation effects on the D-3-hydroxybutyrate dehydrogenase of the heavy and light mitochondria from liver jerboa (Jaculus orient…
2007
The D-3-hydroxybutyrate dehydrogenase (BDH) (EC 1.1.1.30) from liver jerboa (Jaculus orientalis), a ketone body converting enzyme in mitochondria, in two populations of mitochondria (heavy and light) has been studied in different jerboa states (euthermic, prehibernating and hibernating). The results reveal: (1) important variations between states in terms of ketones bodies, glucose and lipid levels; (2) significant differences between the BDH of the two mitochondrial populations in term of protein expression and kinetic properties. These results suggest that BDH leads an important conformational change depending on the physiological state of jerboa. This BDH structural change could be the c…
Sub-critical filtration conditions of commercial hollow-fibre membranes in a submerged anaerobic MBR (HF-SAnMBR) system: The effect of gas sparging i…
2012
A submerged anaerobic MBR demonstration plant with two commercial hollow-fibre ultrafiltration systems (PURON®, Koch Membrane Systems, PUR-PSH31) was operated using municipal wastewater at high levels of mixed liquor total solids (MLTS) (above 22gL -1). A modified flux-step method was applied to assess the critical flux (J C) at different gas sparging intensities. The results showed a linear dependency between J C and the specific gas demand per unit of membrane area (SGD m). J C ranged from 12 to 19LMH at SGD m values of between 0.17 and 0.5Nm 3h -1m -2, which are quite low in comparison to aerobic MBR. Long-term trials showed that the membranes operated steadily at fluxes close to the est…
Experimental study of the anaerobic urban wastewater treatment in a submerged hollow-fibre membrane bioreactor at pilot scale
2011
The aim of this study was to assess the effect of several operational variables on both biological and separation process performance in a submerged anaerobic membrane bioreactor pilot plant that treats urban wastewater. The pilot plant is equipped with two industrial hollow-fibre ultrafiltration membrane modules (PURON¿ Koch Membrane Systems, 30m 2 of filtration surface each). It was operated under mesophilic conditions (at 33°C), 70days of SRT, and variable HRT ranging from 20 to 6h. The effects of the influent COD/SO 4-S ratio (ranging from 2 to 12) and the MLTS concentration (ranging from 6 to 22gL -1) were also analysed. The main performance results were about 87% of COD removal, efflu…
Give us today our daily bread: The effect of hunger on consumers’ visual attention towards bread and the role of time orientation
2021
Abstract This study investigated the effect of hunger on consumers’ visual attention during a food choice task, and the role of time orientation (i.e., present and future orientation) in this interplay. A lab-based eye-tracking experiment including 102 participants was conducted, with hunger as the manipulated factor (hungry, satiated). Participants in the satiated condition were served a breakfast buffet before the experimental tasks, whereas participants in the hungry condition were served the buffet after completion of the tasks. Both groups were exposed to a set of planograms depicting supermarket shelves and were asked to choose an option they could consider buying, while their eye mov…
Experimental Modeling of Submerged Pivot Weir
2020
An inclined rectangular overflow structure, also called a pivot weir, consists of a rectangular plate, angled downstream from the vertical, that can be used as an upstream water level control device. A pivot weir is submerged when the upstream water level is influenced by the downstream flow depth. In this paper, to investigate factors influencing submerged flow conditions, an extensive experimental program including 251 experimental trials was carried out using weir inclination angles of 39.6°, 53°, 85°, and 90° and weir heights ranging from 0.263 to 0.312 m. A formula to distinguish between free and submerged flow conditions was developed using the Π theorem of dimensional analysis and th…
Bench-scale investigation of inclined dense jets
2005
In this work experimental data on the geometry of dense inclined jets issuing in a lab-scale glass rectangular tank are presented. The surrounding fluid was always tap water at room temperature while the dense jets were water solutions of NaCl. Four parameters were changed in the experiments, namely nozzle diameter and inclination, and jet density and flow rate. Jet trajectories were revealed by a colored tracer. Images of the jet were recorded by a digital camera and then further digitally processed, eventually resulting in a time-averaged tracer intensity field. All the jet geometrical parameters, once normalized, were found to be very well correlated to the densimetric Froude number. Mod…
Stable isotopes of water as a tool to study groundwater–seawater interactions in coastal south-eastern Sicily
2009
Summary Stable isotopes of hydrogen (δD) and oxygen (δ 18 O) in groundwater, submarine springs and seawater collected in coastal south-eastern Sicily were investigated. While the spatial distribution of δ 18 O in groundwater showed that most of the heavy-isotope-depleted samples (from −5.7‰ to −6.9‰) were located in the higher portion of the Hyblean Mountains, more positive values (from −3.4‰ to −5.6‰) were found in the marginal areas. The isotope composition of submarine springs was characterized by significant variability (δ 18 O between −5.6‰ and +1.0‰ and δD between −30‰ and +5.0‰) reflecting seasonal variations and different seawater contributions. The isotopic and chemical composition…