Search results for "BM"
showing 10 items of 1459 documents
Altered elemental profile as indicator of homeostatic imbalance in pathogenesis of oral submucous fibrosis
2002
Oral submucous fibrosis (OSF) is a potential precancerous condition of the oral cavity and oropharynx. The etiopathogenesis of this complex precancerous condition is still obscure. In addition to deleterious oral habits, malnutrition, and possible genetic predisposition, altered bioelemental status is also likely to play an important role in its pathogenesis. The present study analyzed 68 elements by inductively coupled plasma-mass spectroscopy in oral mucosa of normal and OSF individuals and some interesting alterations in elemental profile in the diseased tissue have been noted, indicating a homeostatic imbalance. These bioelemental alterations leading to homeostatic imbalance might be co…
Nitric oxide synthase in the enteric nervous system of the guinea-pig: a quantitative description
1994
The distribution and abundance of nitric oxide synthase (NOS)-containing neurons and their terminals in the gastrointestinal tract of the guinea-pig were examined in detail using NADPH diaphorase histochemistry and NOS immunohistochemistry. NOS-containing cell bodies were found in the myenteric plexus throughout the gastrointestinal tract and in the submucous plexus of the stomach, colon and rectum. NOS-containing neurons comprised between 12% (in the duodenum) and 54% (in the esophagus) of total myenteric neurons. In the ileum, NOS neurons represented 19% of total myenteric neurons. Most of the NOS neurons throughout the gastrointestinal tract possessed lamellar dendrites and a single axon…
Cytomorphometric analysis of squames from oral premalignant and malignant lesions
2011
Objective: Oral cytology is becoming increasingly important in the early diagnosis of oral cancer, including epithelial atypia. The aim of this study is to assess the whether the cytoplasmic diameter, nuclear diameter and their nuclear to cytoplasmic ratio are reliable parameters in exfoliative cytology in detecting premalignant and malignant lesions. Study design: Cell and nuclear diameter were measured from the squames of normal buccal mucosal and of oral leukoplakia, oral submucous fibrosis, oral lichen planus which were histologically benign and oral squamous cell carcinoma were measured using an ocular micrometer disc. The nuclear to cytoplasmic ratio in each of these were deduced from…
Proposed new grading of oral submucous fibrosis based on cheek flexibility.
2013
Objectives: Oral submucous fibrosis (OSMF) is a potentially malignant disorder of oral cavity, pharynx and upper digestive tract, characterized by progressive inability to open the mouth. Based on clinical and/or histopathological features, various classifications and grading systems have been put forth till date. The aim of the present study was to study the variance in cheek flexibility in OSMF patients, the observance of which led to the introduction of a new grading for the condition. Material and Methods: The study included 412 patients with OSMF attending to the Department of Oral Medicine and Radiology during the period from December 2008 to June 2013. A detailed history and examinat…
Epithelial-myoepithelial carcinoma of the salivary gland--a low grade malignant neoplasm? Report of two cases and review of the literature.
1999
Summary Epithelial-myoepithelial carcinomas (EMC) are rare neoplasms of the salivary gland with an incidence of less than 1% arising predominantly in the parotid gland. Although they are thought to be of low grade malignancy, fatal courses are described. We report a case of EMC of the parotid gland in a 58-year-old woman with an unfavorable course of this disease in long term follow-up. The malignant potential of this tumor is discussed. In addition, we include another case of EMC of the submandibular gland.
89 Zr-Immuno-Positron Emission Tomography in Oncology: State-of-the-Art 89 Zr Radiochemistry
2017
Contains fulltext : 181624.pdf (Publisher’s version ) (Open Access) Immuno-positron emission tomography (immunoPET) with (89)Zr-labeled antibodies has shown great potential in cancer imaging. It can provide important information about the pharmacokinetics and tumor-targeting properties of monoclonal antibodies and may help in anticipating on toxicity. Furthermore, it allows accurate dose planning for individualized radioimmunotherapy and may aid in patient selection and early-response monitoring for targeted therapies. The most commonly used chelator for (89)Zr is desferrioxamine (DFO). Preclinical studies have shown that DFO is not an ideal chelator because the (89)Zr-DFO complex is partly…
Metastatic Renal Cell Carcinoma to Submandibular Gland: A Rare Occurrence
2015
Approximately 20-30% of patients affected by renal cell carcinoma (RCC) present with metastatic disease, and 20% to 40% undergoing nephrectomy for clinically localized disease will develop metastases. A 53 years old female patient developed a left submandibular swelling. Four years before she experienced a left radical nephrectomy for a clear cell tumor and two years later right kidney was removed for a cancer having the same histologic subtype. In that circumstance duodenal pancreasectomy was required for infiltration of pancreatic gland. A sialoadenectomy has been performed and pathology demonstrated an intraglandular neoplasm with characteristics of a clear renal cell carcinoma. Although…
Modeling of Offshore Crane and Marine Craft in Wave Motion
2020
Safe handling of heavy payloads in an offshore environment requires careful planning and depends on the interaction between a crane and a vessel. This paper investigates the coupled dynamics between a multipurpose crane with payload, and an offshore carrying vessel. A classical multi-body model is derived using holonomic constraints and Newton-Euler kinetics. The resulting index-3 system of differential-algebraic equation (DAE) is transformed into an index-1 system and solved using commonly used numerical ode solvers. Numerical simulations are carried out to show that the proposed models behave in a physically realistic manner. © 2020 IEEE. Personal use of this material is permitted. Permis…
Effect of apolar phase dielectric constant on interfacial properties of β-lactoglobulin (dielectric constant and interfacial properties of β-lactoglo…
2005
International audience; In this work, we hypothesized that the difference in the dielectric constant value existing between two non-miscible phases such as oil and water could be partially responsible for both protein unfolding and reorganization of the protein structure at the interface. So, we replaced the oil phase, whose dielectric constant value is 2, by organic solvents chosen for both their non-miscibility with water and their range of dielectric constant values higher (range 6.1-7.2) than that of oil. Using a dynamic drop tensiometer, we studied both surface activity and viscoelastic properties of the milk protein at various interfaces. The aqueous phase (pH7; 25°C) contained the co…
Citrus aurantium L. Active Constituents, Biological Effects and Extraction Methods. An Updated Review
2021
Citrus genus is a prominent staple crop globally. Long-term breeding and much hybridization engendered a myriad of species, each characterized by a specific metabolism generating different secondary metabolites. Citrus aurantium L., commonly recognized as sour or bitter orange, can exceptionally be distinguished from other Citrus species by unique characteristics. It is a fruit with distinctive flavor, rich in nutrients and phytochemicals which possess different health benefits. This paper presents an overview of the most recent studies done on the matter. It intends to provide an in-depth understanding of the biological activities and medicinal uses of active constituents existing in C. au…