Search results for "BOC"
showing 10 items of 477 documents
Flemón parafaríngeo por cuerpo extraño metálico
1998
Los flemones y abcesos parafaríngeos, comunes en la era preantibiótica, son actualmente una entidad poco frecuente. Es necesario un diagnóstico y actitud terapéutica precoz para impedir acrecentar la morbimortalidad asociada. La mayoría de casos descritos se deben a perforaciones de faringe y esófago o por complicación de infecciones del tracto aerodigestivo superior. en un 15% de los casos nos encontraremos con una fase previa al abceso, denominada celulitis, sin que se haya formado colección purulenta, que puede ser solucionado con tratamiento antibiótico sin precisar drenaje quirúrgico. La paciente que presentamos empezó a referir sintomatología después de veinte años de permanencia de u…
Clinical and radiological course in apicoectomies with the Erbium : YAG LASER
2007
A study is made of the efficacy of the Erbium: YAG laser in granulomatous periapical lesions, based on clinical and radiographic controls. The study comprised a series of 45 patients amenable to periapical surgical treatment of incisors, canines and premolars. A conventional surgical technique was used, with silver amalgam retrograde filling and irradiation of the bone defect and remnant root cement with the Erbium: YAG laser. Clinical and radiographic controls were made during 24 months, assessing the absence of symptoms and the presence of pain, swelling or fistula and ossification of the lesions, respectively. The clinical course proved asymptomatic in 95.5% of the cases. As regards remo…
ISomerization of xylene: MINDO/3 study of the cyclization of benzenium cation into bicyclo[3.1.0]hexenyl cation
1989
Abstract A MINDO/3 study of thermal electrocyclic closing of the benzenium cation to form a bicyclo[3.1.0]hexenyl cation is presented. The calculated mechanism discusses the possibility of cyclization of xylenium cations on a silica catalyst or in superacid media. The structure and energy of the transition state, the enthalpies of isomerization and barriers of activation were calculated for the following processes: isomerization of 2,6-dimethylbenzenium cation into 2,6-dimethylbicyclo[3.1.0]hexenyl cation, isomerization of 2,4-dimethylbenzenium cation into 2,4-dimethylbicyclo[3.1.0]-hexenyl cation, and isomerization of benzenium cation into bicyclo[3.1.0]-hexenyl cation. Equilibrium and kin…
I laureati triennali
2010
Oral cancer risk and molecular markers
2004
El aspecto clínico y en especial el grado de displasia que pueden presentar las lesiones precancerosas de la cavidad oral sugieren su capacidad potencial de malignización. Cada vez es más frecuente encontrar investigaciones orientadas hacia la búsqueda de nuevos marcadores, más específicos, que contribuyan a determinar el grado de alteración celular y permitan una mayor aproximación al conocimiento del grado de degeneración maligna de aquellas lesiones. En el presente trabajo de revisión se repasan los conceptos más actuales de estos marcadores, agrupados por familias: marcadores de crecimiento tumoral; marcadores de supresión tumoral y de respuesta antitumoral; marcadores de angiogénesis; …
ChemInform Abstract: Synthesis of Sesquiterpenes via Silicon-Guided Rearrangement of Epoxydecalins
2009
A survey of the rearrangement of methyldecalins via C-5 carbocation intermediates, with special attention to the silicon-guided rearrangement of epoxydecalins is provided. A TMS group properly posi...
Silicon guided rearrangement of epoxydecalines to spirocyclic compounds. Synthesis of gleenol and axenol from carvone
2005
Abstract The synthesis of the spirocyclic sesquiterpenes (−)-gleenol and (−)-axenol in enantiomerically pure form has been achieved starting from R-(−)-carvone. The key step is the silicon guided acid-promoted rearrangement of a 9-trimethylsilyl-5,6-epoxy-noreudesmane prepared from 3-trimethylsilyldihydrocarvone in several steps involving Robinson annulation, enone deconjugation and epoxidation. Acid treatment of the epoxy-noreudesmane gave a norspiroaxane as the main product, which was used as intermediate for the synthesis of two naturally occurring sesquiterpenes gleenol and axenol.
Thrombotic thrombocytopenic purpura (TTP) leading to pseudotumour's autoimmune pancreatitis (AIP): A case report
2012
International audience; Introduction: Autoimmune pancreatitis is an idiopathic inflammatory disease that produces pancreatic masses and ductal strictures. This benign disease can be associated with extrapancreatic manifestations including cholangitis, sialadenitis, inflammatory bowel disease or retroperitoneal fibrosis, mediastinal adenopathy, interstitial nephritis mainly due to immunoglobulin G4 (Ig G4), and occasional association with other auto-immune diseases. Observation: We report a 57-year-old woman who developed thrombotic thrombocytopenic purpura (UP) and pseudo-tumour's seronegative autoimmune pancreatitis (ATP) type 1. The patient was initially treated with pulse corticosteroids…
Anemia during treatment with peginterferon Alfa-2b/ribavirin and boceprevir: Analysis from the serine protease inhibitor therapy 2 (SPRINT-2) trial
2013
International audience; Boceprevir (BOC) added to peginterferon alfa-2b (PegIFN) and ribavirin (RBV) significantly increases sustained virologic response (SVR) rates over PegIFN/RBV alone in previously untreated adults with chronic hepatitis C genotype 1. We evaluate the relationship of incident anemia with triple therapy. A total of 1,097 patients received a 4-week lead-in of PegIFN/RBV followed by: (1) placebo plus PegIFN/RBV for 44 weeks (PR48); (2) BOC plus PegIFN/RBV using response-guided therapy (BOC/RGT); and (3) BOC plus PegIFN/RBV for 44 weeks (BOC/PR48). The management of anemia (hemoglobin [Hb]<10 g/dL) included RBV dose reduction and/or erythropoietin (EPO) use. A total of 1,080…
Value of bone marrow biopsy in the diagnosis of essential thrombocythemia.
2004
Background and Objectives. Essential thrombocythemia (ET) is a Philadelphia chromosome-negative chronic myeloproliferative disorder (CMPD) whose diagnosis, according to the Polycythemia Vera Study Group (PVSG) criteria, does not include histopathological data. The new WHO classification of CMPD has supplied new diagnostic guidelines which highlight the value of histopathology and facilitate a more precise differentiation of ET from reactive conditions and other CMPD. Design and Methods. Bone marrow biopsies from 142 adult patients diagnosed with ET according to PVSG criteria were evaluated using the new WHO classification. Megakaryocyte morphology and arrangement, amount of fibrosis and a c…