Search results for "BORO"

showing 10 items of 466 documents

Substituent effects on the reaction mode between 2-hydroxybenzyl alcohol derivatives and MEM chloride:synthesis and mechanistic aspects of seven-and …

2004

Abstract The synthesis of (RS)-2- or (RS)-3-methoxy-2,3-dihydro-5H-1,4-benzodioxepins and (RS)-5- or (RS)-3-methoxy-2,3,5,6-tetrahydro-8H-benzo-[1,4,7]-trioxecins has been developed. The mechanism of such a reaction via the boron trifluoride etherate-promoted transformation of 2-(methoxyethoxymethoxy)benzyloxyacetaldehyde dimethyl acetals or 2-(methoxyethoxymethoxymethyl)phenyloxyacetaldehyde dimethyl acetals has been proposed. Transannular versions of the reaction results in the facile ring contraction of 12-membered intermediates to the 10- and to 7-membered benzene-fused O,O-acetals. The characterization of the by-products strongly supports the mechanisms proposed.

AcetalChemistryStereochemistryOrganic ChemistrySubstituentAlcoholBiochemistryChlorideBenzodioxepinchemistry.chemical_compoundMedium-ring heterocycleDrug DiscoverymedicineBoron trifluoridemedicine.drug
researchProduct

Effect of boron oxide on the microstructure of mullite-based glass-ceramic glazes for floor-tiles in the CaO–MgO–Al2O3–SiO2 system

2006

Abstract The effect of increasing replacement of Al2O3 by B2O3 in a parent glass on the sintering and further crystallization of mullite was investigated. The composition of the parent glass was chosen in the mullite primary phase field of the CaO–MgO–Al2O3–SiO2 quaternary system. Glass powder pellets were heated under standard (10 °C/min and 2 h of hold time) and fast heatings (25 °C/min and 5 min of hold time) at different temperatures from 700 to 1190 °C. Sintering of B2O3-containing glasses took place in the range between 850 and 1050 °C. X-ray diffraction results showed that mullite formed as unique crystalline phase for glasses containing amounts of B2O3 larger than 6 wt%. For lower a…

AcicularMaterials scienceGlass-ceramicRietveld refinementMetallurgySinteringMineralogyMulliteMicrostructurelaw.inventionBoron oxidelawMaterials ChemistryCeramics and CompositesCrystallizationJournal of the European Ceramic Society
researchProduct

A Series of Ultra-Efficient Blue Borane Fluorophores

2020

13 pags., 14 figs., 5 tabs.

Active laser mediumSeries (mathematics)010405 organic chemistryHydridechemistry.chemical_elementBoraneAlkylation010402 general chemistryLaser01 natural sciencesCombinatorial chemistry0104 chemical scienceslaw.inventionInorganic Chemistrychemistry.chemical_compoundchemistrylawPhysical and Theoretical ChemistryBoron
researchProduct

Superiority of the Triple Combination of Bortezomib-Thalidomide-Dexamethasone Over the Dual Combination of Thalidomide-Dexamethasone in Patients With…

2012

Purpose This prospective multicenter phase III study compared the efficacy and safety of a triple combination (bortezomib-thalidomide-dexamethasone [VTD]) versus a dual combination (thalidomide-dexamethasone [TD]) in patients with multiple myeloma (MM) progressing or relapsing after autologous stem-cell transplantation (ASCT). Patients and Methods Overall, 269 patients were randomly assigned to receive bortezomib (1.3 mg/m2 intravenous bolus) or no bortezomib for 1 year, in combination with thalidomide (200 mg per day orally) and dexamethasone (40 mg orally once a day on 4 days once every 3 weeks). Bortezomib was administered on days 1, 4, 8, and 11 with a 10-day rest period (day 12 to day …

AdultMaleCancer Researchmedicine.medical_specialtyTransplantation AutologousGastroenterologyDexamethasoneDisease-Free SurvivalDrug Administration ScheduleSettore MED/01 - Statistica MedicaBortezomib03 medical and health sciences0302 clinical medicineRecurrenceInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansAutologous transplantationSurvival rateMultiple myelomaDexamethasoneAgedBortezomibbusiness.industryHazard ratioTranslational research Immune Regulation [ONCOL 3]Middle Agedmedicine.diseaseBoronic AcidsThalidomide3. Good healthSurgeryThalidomideTransplantationTreatment OutcomeOncologyPyrazines030220 oncology & carcinogenesisFemaleMultiple MyelomabusinessStem Cell Transplantation030215 immunologymedicine.drugJournal of Clinical Oncology
researchProduct

Intravenous injection of bortezomib, melphalan and dexamethasone in refractory and relapsed multiple myeloma

2013

Abstract Background A combination of bortezomib (1.3 mg/m2), melphalan (5 mg/m2), and dexamethasone (40 mg) (BMD), with all three drugs given as a contemporary intravenous administration, was retrospectively evaluated. Patients and methods Fifty previously treated (median 2 previous lines) patients with myeloma (33 relapsed and 17 refractory) were assessed. The first 19 patients were treated with a twice-a-week (days 1, 4, 8, 11, ‘base’ schedule) administration while, in the remaining 31 patients, the three drugs were administered once a week (days 1, 8, 15, 22, ‘weekly’ schedule). Results Side-effects were predictable and manageable, with prominent haematological toxicity, and a better tox…

AdultMaleMelphalanmedicine.medical_specialtyDrug-Related Side Effects and Adverse ReactionsSalvage therapyGastroenterologyDexamethasoneDisease-Free SurvivalDrug Administration ScheduleBortezomibRefractoryRecurrenceInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansProgression-free survivalMelphalanMultiple myelomaDexamethasoneAgedRetrospective StudiesAged 80 and overBortezomibbusiness.industryHematologyMiddle Agedmedicine.diseaseBoronic AcidsRegimenTreatment OutcomeOncologyPyrazinesInjections IntravenousFemaleMultiple MyelomabusinessFollow-Up Studiesmedicine.drug
researchProduct

Selective Introduction of Acid Sites in Different Confined Positions in ZSM-5 and Its Catalytic Implications

2018

Controlling the location of acid sites in zeolites can have a great effect on catalysis. In this work we face the objective of directing the location of Al into the 10R channels of ZSM-5 by taking advantage of the structural preference of B to occupy certain positions at the channel intersections, as suggested by theoretical calculations. The synthesis of B-Al-ZSM-5 zeolites with variable Si/Al and Si/B ratios, followed by B removal in a postsynthesis treatment, produces ZSM-5 samples enriched in Al occupying positions at 10R channels. The location of the acid sites is determined on the basis of the product distribution of 1-hexene cracking as a test reaction. The higher selectivity to prop…

Al siting02 engineering and technology010402 general chemistryFluid catalytic cracking01 natural sciencesDFTCatalysisCatalysisPropenechemistry.chemical_compoundQUIMICA ORGANICABoron ZSM-5General Chemistry021001 nanoscience & nanotechnologyProduct distribution0104 chemical sciencesCrystallographyCrackingchemistryCatalytic crackingZeolitesMethanolZSM-5MTO0210 nano-technologySelectivityACS Catalysis
researchProduct

ESR response to gamma-rays of alanine pellets containing B(OH)3 or Gd2O3.

2007

ESR response to gamma-irradiation (1-50 Gy) of blends containing alanine and either B(OH)(3) or Gd(2)O(3) is reported. The sensitivity of the alanine--B(OH)(3) blend is comparable to the sensitivity of pure alanine, although its lowest detectable dose, LDD, is smaller ( approximately 1.3 Gy) than that of pure alanine ( approximately 2.9 Gy). Alanine with Gd(2)O(3) is about two times more sensitive than pure alanine, and its LDD is 0.8 Gy. The better sensitivity and LDD are probably due to the high atomic number (Z=64) of gadolinium, which enhances the interaction probability with photons and, consequently, the radical yield. This study suggests that other high-Z atoms may be useful for incr…

AlanineHigh atomic numberRadiationAlanineGadoliniumRadiochemistryPelletsElectron Spin Resonance Spectroscopychemistry.chemical_elementGadoliniumESR; Alanine; B(OH)3; Gd2O3; Sensitivity; Mass energy absorption coefficientMass energy absorption coefficientSensitivitychemistryBoric AcidsIsotopesGd2O3Gamma RaysYield (chemistry)RadiometryB(OH)3ESRBoronApplied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
researchProduct

Substituent effect on ammonia–borane donor–acceptor complexes: a G2(MP2) molecular orbital study

1998

Abstract H3BNHnMe3−n and Me3−nHnBNH3 (n=0–3) donor–acceptor complexes have been studied using the G2(MP2) method. Predicted equilibrium structures and dissociation energies have been correlated to the degree of substitution on the donor and the acceptor separately. It is found that successive methyl substitutions on boron reduce the dissociation energies of the complexes, contrary to the successive substitutions on nitrogen. The NBO partitioning scheme suggests that there is no correlation between the charge transfer and the dissociation energies. These results are interpreted in terms of the changes in the HOMO−LUMO gap, the type of acceptor and donor involved, and distortion of the accept…

Ammonia boraneSubstituentchemistry.chemical_elementCondensed Matter PhysicsPhotochemistryBiochemistryNitrogenAcceptorDissociation (chemistry)chemistry.chemical_compoundchemistryMolecular orbitalPhysical and Theoretical ChemistryBoronNatural bond orbitalJournal of Molecular Structure: THEOCHEM
researchProduct

Effect of sodium to barium substitution on the space charge implementation in thermally poled glasses for nonlinear optical applications

2009

Thermally poled niobium borophosphate glasses in the system 0.55(0.95-y) NaPO{sub 3}+y/2 Ba(PO{sub 3}){sub 2}+0.05Na{sub 2}B{sub 4}O{sub 7})+0.45Nb{sub 2}O{sub 5} were investigated for second order optical nonlinear (SON) properties. Bulk glasses were studied by Raman spectroscopy, thermal analysis, optical and dielectric measurements. The sodium to barium substitution does not lead to significant changes in optical properties, crystallization of glasses and coordination environment of polarizable niobium atoms. However, the ionic conductivity decreases drastically with the increase of barium concentration. Secondary ion mass spectroscopy has been used to determine the element distribution …

Analytical chemistryNiobiumchemistry.chemical_element02 engineering and technologyDielectric01 natural sciencesSpace chargeInorganic Chemistrysymbols.namesakeIonic conductivity0103 physical sciencesMaterials ChemistryPhysical and Theoretical Chemistry010302 applied physicsThermal polingSecond-harmonic generationNonlinear opticsBarium[CHIM.MATE]Chemical Sciences/Material chemistrySecond harmonic generation021001 nanoscience & nanotechnologyCondensed Matter PhysicsSpace chargeElectronic Optical and Magnetic MaterialschemistryBorophosphate glasses[ CHIM.MATE ] Chemical Sciences/Material chemistryContent (measure theory)Ceramics and Compositessymbols0210 nano-technologyRaman spectroscopy
researchProduct

Highly Selective Detection of Nerve‐Agent Simulants with BODIPY Dyes

2014

Two chromo-fluorogenic probes, each based on the boron dipyrromethene core, have been developed for the detection of nerve-agent mimics. These chemosensors display both a color change and a significant enhancement of fluorescence in the presence of diethylcyanophosphonate (DCNP) and diisopropylfluorophosphate (DFP). No interference from other organophosphorus compounds or acids has been observed. Two portable chemosensor kits have been developed and tested to demonstrate its practical application in real-time monitoring.

Analytical chemistrysensorsCatalysischemistry.chemical_compoundQUIMICA ORGANICAfluorescent probesmedicinePhosphorylationColoring AgentsBoronFluorescent DyesNerve agentNeurological agentsMolecular StructurephosphorylationChemistryQUIMICA INORGANICAOrganic ChemistryGeneral ChemistryHighly selectiveCombinatorial chemistryFluorescenceBODIPYboronmedicine.drugChemistry – A European Journal
researchProduct