Search results for "BOX"
showing 10 items of 2676 documents
Out-of-box experience : noviisikäyttäjien ensikokemukset kamerapuhelimista
2005
Sustainable design: study of the life cycle assessment of the production and packaging of wine
2003
The object of the study is the identification of the factors that interact with the environment during the production and the packaging of wine. For this aim is use an Economic Input-Output Life -Cycle assessment (EIO-LCA) and I-LCA database to access both the direct and indirect effects of supply chain on the environment and economy. In this phase is examines the impact on the environment by different types of packaging, and transport, the comparisons are made analyses energy, materials consumption and emissions in the environment.
RUNX3 and T-Bet in Immunopathogenesis of Ankylosing Spondylitis—Novel Targets for Therapy?
2019
Susceptibility to ankylosing spondylitis (AS) is polygenic with more than 100 genes identified to date. These include HLA-B27 and the aminopeptidases (ERAP1, ERAP2, and LNPEPS), which are involved in antigen processing and presentation to T-cells, and several genes (IL23R, IL6R, STAT3, JAK2, IL1R1/2, IL12B, and IL7R) involved in IL23 driven pathways of inflammation. AS is also strongly associated with polymorphisms in two transcription factors, RUNX3 and T-bet (encoded by TBX21), which are important in T-cell development and function. The influence of these genes on the pathogenesis of AS and their potential for identifying drug targets is discussed here.
cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel
2020
Abstract Background Resistance to enteric pathogens is a complex trait at the crossroads of multiple biological processes. We have previously shown in the Drosophila Genetic Reference Panel (DGRP) that resistance to infection is highly heritable, but our understanding of how the effects of genetic variants affect different molecular mechanisms to determine gut immunocompetence is still limited. Results To address this, we perform a systems genetics analysis of the gut transcriptomes from 38 DGRP lines that were orally infected with Pseudomonas entomophila. We identify a large number of condition-specific, expression quantitative trait loci (local-eQTLs) with infection-specific ones located …
Power holders: one versus many. Leadership and elite theories
2016
‘Leadership’ and ‘elites’ are two crucial concepts that refer to individuals who hold power within a community. The aim of the article was to demonstrate to what extent the two concepts and theories are linked with each other in the literature. A quantitative and qualitative content analysis of the encyclopedic and dictionary entries demonstrates a divergence of approaches: on the one hand, a fundamental separation between the two theories, while on the other hand, a tendency to identify the one with the other. This shows the need for much more dialog between the frameworks of these two closely related phenomena.
Crop Nitrogen Retrieval Methods for Simulated Sentinel-2 Data Using In-Field Spectrometer Data.
2021
Nitrogen (N) is one of the key nutrients supplied in agricultural production worldwide. Over-fertilization can have negative influences on the field and the regional level (e.g., agro-ecosystems). Remote sensing of the plant N of field crops presents a valuable tool for the monitoring of N flows in agro-ecosystems. Available data for validation of satellite-based remote sensing of N is scarce. Therefore, in this study, field spectrometer measurements were used to simulate data of the Sentinel-2 (S2) satellites developed for vegetation monitoring by the ESA. The prediction performance of normalized ratio indices (NRIs), random forest regression (RFR) and Gaussian processes regression (GPR) f…
Jauno tehnoloģiju pielietojums datu noliktavās
2015
Maģistra darbs „Jauno tehnoloģiju pielietojums datu noliktavās” balstās uz lielo datu analīzes realizācijas problēmu datu noliktavās. Darba mērķis ir izpētīt jaunās tehnoloģijas datu noliktavās un lielo datu apstrādes platformas piemērotību datu analīzes veikšanai praktiski realizējot iepriekš definētu lietojuma gadījumu. Rezultātā tika izpētītas lielo datu tehnoloģijas, kuras jau pielieto datu noliktavu risinājumos, un praktiski realizēts lietojuma gadījums datu analīzei izmantojot lielo datu apstrādes platformu Hortonworks, kā arī apzīmēts tālākais iespējamais datu noliktavu attīstības virziens lielo datu laikmetā.
Apoptotic-like Leishmania exploit the host´s autophagy machinery to reduce T-cell-mediated parasite elimination
2015
Apoptosis is a well-defined cellular process in which a cell dies, characterized by cell shrinkage and DNA fragmentation. In parasites like Leishmania, the process of apoptosis-like cell death has been described. Moreover upon infection, the apoptotic-like population is essential for disease development, in part by silencing host phagocytes. Nevertheless, the exact mechanism of how apoptosis in unicellular organisms may support infectivity remains unclear. Therefore we investigated the fate of apoptotic-like Leishmania parasites in human host macrophages. Our data showed--in contrast to viable parasites--that apoptotic-like parasites enter an LC3(+), autophagy-like compartment. The compartm…
Low-weight carboxylic acids as potential risk factor of compost phytotoxicity
2009
Being intermediates of organic matter degradation, low-weight carboxylic acids (LWCA) can occur at phytotoxic concentrations on bioactive soils or in the processed organic material applied to soil. While toxicity potentials and mixture effects of LWCA are still poorly known, the potential phytotoxicity of the biomaterials is difficult to assess. In the study effective concentrations (EC) of formic, acetic and propionic acids at non adjusted pH were obtained in short-term germination assays (48 h for cress, Lepidium sativum, and 120 h for ryegrass Lolium multiflorum) and subchronic growth assays (21d). Based on the EC values, LWCA inhibited more strongly plant growth than seed germination. I…