Search results for "Bach"

showing 10 items of 571 documents

Aclidinium inhibits human lung fibroblast to myofibroblast transition

2011

Background Fibroblast to myofibroblast transition is believed to contribute to airway remodelling in lung diseases such as asthma and chronic obstructive pulmonary disease. This study examines the role of aclidinium, a new long-acting muscarinic antagonist, on human fibroblast to myofibroblast transition. Methods Human bronchial fibroblasts were stimulated with carbachol (10 −8 to 10 −5  M) or transforming growth factor-β1 (TGF-β1; 2 ng/ml) in the presence or absence of aclidinium (10 −9 to 10 −7  M) or different drug modulators for 48 h. Characterisation of myofibroblasts was performed by analysis of collagen type I and α-smooth muscle actin (α-SMA) mRNA and protein expression as well as α…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyCarbacholChronic Obstructive Pulmonary DiseaseBronchiMuscarinic AntagonistsBiologyCholinergic AgonistsCollagen Type ITransforming Growth Factor beta1Downregulation and upregulationWestern blotanticholinergicCell MovementInternal medicinemedicineCOPDHumans1506RNA MessengerAutocrine signallingFibroblastMyofibroblastsCells CulturedCell Proliferationmedicine.diagnostic_testDose-Response Relationship Drugairway epitheliumCell Differentiationasthmainterstitial fibrosisFibroblastsAdenosineMolecular biologymyofibroblastActinsUp-RegulationEndocrinologymedicine.anatomical_structurePhosphorylationFibroblastCarbacholMyofibroblastmedicine.drugTropanesThorax
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Cross-cultural adaptation and test-retest reliability of the spanish ROWAN foot pain assessment questionnaire (ROFPAQ-S)

2020

Background The ROWAN Foot Pain Assessment Questionnaire (ROFPAQ) may be considered as a self-reported health questionnaire with 45 items to measure foot health problems such as foot pain. To date, the ROFPAQ has only been validated into an English-language version. Objectives Therefore this study aim was to perform the cross-cultural adaptation and test-retest reliability of the Spanish ROFPAQ version (ROFPAQ-S). Study design A cross-sectional descriptive study. Settings Podiatry and physiotherapy clinical centers. Methods The recommended forward/backward translation protocol was applied for the procedure of translation and cross-cultural adaptation from United Kingdom to Spain. Results An …

Quality of lifeAdultCross-Cultural ComparisonMalemedicine.medical_specialtyIntraclass correlationCalidad de vidaPainChronic painEnquestesFoot DiseasesQuality of lifeCronbach's alphaPain assessmentSurveys and QuestionnairesMedicineHumansTranslationsReliability (statistics)LanguagePain MeasurementFootHealth impact assessmentbusiness.industryPiePodiatryChronic painReproducibility of ResultsMiddle AgedDolor crónicomedicine.diseasePatologiaTest (assessment)ExtremitatsEstudios de validaciónAnesthesiology and Pain MedicineCross-Sectional StudiesValidation studiesSpainPhysical therapyFemalebusiness
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Parental-caregiver perceptions of child oral health-related quality of life (P-CPQ): Psychometric properties for the peruvian spanish language.

2013

Objectives: The aim of the study was to cross-culturally adapt the Parental-Caregiver Perceptions Questionnaire (P-CPQ) to the Peruvian Spanish language and assess its reliability and validity. Study Design: To translate and cross-cultural adapt the instrument, 60 parents answered the P-CPQ in two pilot tests. The final version of the P-CPQ was evaluated in 200 parents of children aged 11 to 14 years, who were clini - cally examined for dental caries. The internal consistency was assessed by Cronbach's alpha coefficient while repeat administration of the P-CPQ on the same 200 children facilitated the test-retest reliability via intraclass correlation coefficient (ICC). Construct and discrim…

Quality of lifeMaleParentsvalidityPsychometricsAdolescentPsychometricsIntraclass correlationOdontologíaOral HealthDevelopmental psychologyQuality of life (healthcare)childrenCronbach's alphaSurveys and QuestionnairesPeruHumansChildGeneral DentistryReliability (statistics)LanguagereliabilityCultural CharacteristicsOral Medicine and PathologyResearchDiscriminant validityConstruct validityReproducibility of Results:CIENCIAS MÉDICAS [UNESCO]//purl.org/pe-repo/ocde/ford#3.02.14 [https]Ciencias de la saludOtorhinolaryngologyCaregiversScale (social sciences)UNESCO::CIENCIAS MÉDICASQuality of Lifeoral healthSurgeryFemalePsychologyClinical psychologyMedicina oral, patologia oral y cirugia bucal
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Validation of the Italian version of the abbreviated expanded prostate Cancer index composite (EPIC-26) in men with prostate Cancer

2019

Abstract Background This study aims to validate and evaluate the psychometric properties and reliability of the Italian version of the Expanded Prostate Cancer Index Composite – Short Form (EPIC-26), a measure of quality of life (QoL) for prostate cancer patients. Methods Two hundred and eighty-four prostate cancer patients completed the Italian version of the EPIC-26 questionnaire at 45 days (T1) and 3 months (T2) after robot-assisted radical prostatectomy (RARP). Psychometric properties were evaluated using structural equation modeling: the goodness of fit of the correlated five-factor model (CFFM) for the EPIC-26 was assessed using the confirmatory factor analysis (CFA), while longitudin…

Quality of lifeMalemedicine.medical_specialtymedicine.medical_treatmentlcsh:Computer applications to medicine. Medical informatics03 medical and health sciencesProstate cancer0302 clinical medicineGoodness of fitQuality of lifeCronbach's alphaSurveys and QuestionnairesValidationmedicineHumansMeasurement invarianceTranslations030212 general & internal medicineReliability (statistics)AgedProstatectomyProstate cancerProstatectomybusiness.industry030503 health policy & servicesResearchPublic Health Environmental and Occupational HealthProstatic NeoplasmsReproducibility of ResultsGeneral MedicineMiddle Agedmedicine.diseaseConfirmatory factor analysisItalyPhysical therapyEpic-26lcsh:R858-859.70305 other medical sciencebusinessDecision-makingHealth and Quality of Life Outcomes
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Cross-cultural adaptation and validation of the French version of the Knee injury and Osteoarthritis Outcome Score (KOOS) in knee osteoarthritis pati…

2008

Udgivelsesdato: 2008-Apr OBJECTIVE: To adapt the Knee injury and Osteoarthritis Outcome Score (KOOS) into French and to evaluate the psychometric properties of this new version. METHODS: The French version of the KOOS was developed according to cross-cultural guidelines by using the "translation-back translation" method to ensure content validity. KOOS data were then obtained in patients with symptomatic knee osteoarthritis (OA). The translated questionnaire was evaluated in two knee OA population groups, one with no indication for joint replacement (medicine), and the other waiting for joint replacement (surgery). The psychometric properties evaluated were feasibility: percentage of respon…

QuestionnairesAdultCross-Cultural ComparisonMalemedicine.medical_specialtyPsychometricsPsychometricsJoint replacementmedicine.medical_treatmentCross-cultural validationPopulationBiomedical EngineeringOsteoarthritisSeverity of Illness IndexPhysical medicine and rehabilitationQuality of lifeCronbach's alphaRheumatologySurveys and QuestionnairesmedicineHumansTranslationsOrthopedics and Sports MedicineeducationAgedAged 80 and overeducation.field_of_studyKOOSbusiness.industryConstruct validityReproducibility of ResultsMiddle AgedOsteoarthritis Kneemedicine.diseasePhysical therapyQuality of LifeCeiling effectFemaleKnee osteoarthritisFrancebusinessOsteoarthritis and Cartilage
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An instrument to measure nurses’ knowledge in palliative care: Validation of the Spanish version of Palliative Care Quiz for Nurses

2017

Background Palliative care is nowadays essential in nursing care, due to the increasing number of patients who require attention in final stages of their life. Nurses need to acquire specific knowledge and abilities to provide quality palliative care. Palliative Care Quiz for Nurses is a questionnaire that evaluates their basic knowledge about palliative care. The Palliative Care Quiz for Nurses (PCQN) is useful to evaluate basic knowledge about palliative care, but its adaptation into the Spanish language and the analysis of its effectiveness and utility for Spanish culture is lacking. Purpose To report the adaptation into the Spanish language and the psychometric analysis of the Palliativ…

QuestionnairesPalliative carePsychometricsPsychometricsHealth Care Providerslcsh:MedicineNursesSocial SciencesResearch and Analysis Methods03 medical and health sciencesNursing care0302 clinical medicineCronbach's alphaNursingInfermeria030502 gerontologyItem response theoryMedicine and Health SciencesContent validityPsychologyPain ManagementMedicine030212 general & internal medicinelcsh:ScienceLanguageSurvey ResearchMultidisciplinarybusiness.industrylcsh:RPalliative CareCognitive PsychologyBiology and Life SciencesPilot StudiesTest (assessment)Health CareComprehensionProfessionsResearch DesignTractament pal·liatiuPeople and PlacesCognitive Sciencelcsh:QPopulation Groupings0305 other medical sciencebusinessResearch ArticleNeuroscienceAcute Pain Management
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Absorption edge in silica glass

2005

Measurements of optical absorption in the v-UV range in a variety of silica glass are used to determine the width of the absorption edge (Urbach energy). Measured values range from 60 meV up to 180 meV. So high a variability over silica types is tentatively ascribed to the different disorder degree, which characterizes different materials.

Range (particle radiation)Materials scienceOptical glassSilica glassbusiness.industryCrystalline materialsSettore FIS/01 - Fisica SperimentaleAnalytical chemistryPhysics::OpticsCondensed Matter::Disordered Systems and Neural NetworksAmorphous solidOpticsAbsorption edgeOptical materialsUrbach energySilica glastructural disorder.Absorption (electromagnetic radiation)business
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Translation, Adaption, and Psychometric Testing of the Myanmar Version of the Medical Outcomes Study Social Support Survey for People Living With HIV…

2021

Introduction: Valid and reliable instruments are crucial for measuring perceived social support among people living with HIV (PLHIV). We aimed to investigate the psychometric properties of the English version of the 19-item Medical Outcomes Study Social Support Survey (MOS-SSS) adapted for PLHIV in Myanmar.Methods: Based on a standard cross-cultural procedure, we adapted the MOS-SSS and formed a Myanmar version of the scale (MOS-SSS-M), and then tested its validity and reliability. A sample of 250 eligible PLHIV was collected from a closed Facebook group that included more than 10,000 Myanmars, most of whom were PLHIV.Results: The MOS-SSS-M achieved a Cronbach’s α of 0.82–0.95. Confirmatory…

Rasch modelValidityConstruct validityHIVMyanmarsocial supportmedicine.diseaseConfirmatory factor analysishumanitiesBF1-990Social supportpsychometric adaptationAcquired immunodeficiency syndrome (AIDS)Cronbach's alphaClinical ResearchScale (social sciences)Behavioral and Social SciencemedicinePsychologyCognitive SciencessurveyPsychologyGeneral PsychologyOriginal ResearchClinical psychologyFrontiers in psychology
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CHILDREN’S DEPRESSION RATING SCALE-REVISED (CDRS-R) – DEVELOPMENT OF THE LATVIAN VERSION AND PSYCHOMETRIC PROPERTIES IN A CLINICAL AND NON-CLINICAL S…

2019

Depression is one of the most widespread mental disorders worldwide. Adolescence is a vulnerable period for developing depression. It is associated with a number of challenges in biological, psychological and social areas. Valid and reliable measurement instruments are required for assessment of symptoms of depression in clinical samples of adolescents in Latvia. Children's Depression Rating Scale Revised (CDRS-R, Posnanski & Mokros, 1996) is a semi-structured, clinician-rated interview for assessment of depression in children and adolescents. While the CDRS-R is the most widely used rating scale for research and clinicians’ practical use worldwide, there's no validated version in Latvi…

Receiver operating characteristicbusiness.industryConcordanceLatvianlanguage.human_languageassessment; adolescents; CDRS-R; depressive disorders; psychometric propertiesCronbach's alphaRating scalelanguageMedicinebusinessReliability (statistics)Depression (differential diagnoses)Clinical psychologyRank correlationSOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference
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Quitter sa région pour entrer à l'université

2006

This paper aims at understanding the regional mobility of new entrants to university. The regionalmobility is marginal. But, the impact of social and academic characteristics shows that selfselection processes exist. The combine effects of fields and regions impacts highlight the role ofavailability of university program on student choice.

RegionsUniversityUniversitéMobilité géographique[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/Education[ SHS.EDU ] Humanities and Social Sciences/EducationRégionEtudiantStudent choicesBachelierMigrationParcours de formation
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