Search results for "Barbiturate"

Protection effect of endurance training against reoxygenation-induced injuries in rat heart

1990

Endurance training by swimming (219-229 h) resulted in a significant protection against hypoxia/reoxygenation-induced injuries in Langendorff-perfused rat hearts. The protection was manifested as improved flow characteristics and a smaller release of creatine kinase into the perfusate. The concentration of thiobarbituric acid reactive substances (TBARS) was lower in the trained than in the respective control hearts. The trained hearts also showed a lower reoxygenation-induced increase in TBARS. The myocardium of the right ventricle and that of the left subepimyocardium were the most affected by reoxygenation. The swimming program induced a decrease in the activities of catalase and glutath…

�ber den Einflu� von Barbituraten, Thiobarbituraten und Barbiturs�ure auf cellul�re Potentiale und Kontraktionen des Meerschweinchenvorhofes

1962

An elektrisch gereizten Meerschweinchen-Vorhofen wurde der Einflus von Hexobarbital, Pentobarbital, Thiopental, Methitural und Barbitursaure auf die cellularen Potentiale und das Mechanogramm vergleichend untersucht. Beiniedrigen Konzentrationen (bei Methitural ab 7 · 10−6 g/ml) verursachen alle Barbiturate und Thiobarbiturate zunachst eine Verlangerung der 90% igen Repolarisationszeit (RZ), bei hohen Konzentrationen (bei Methitural ab 3 · 10−5 g/ml) eine zunehmende Verkurzung der 20%-, 50%- und 90%-RZ. Bei sehr hohen Konzentrationen (bei den Thiobarbituraten ab 8 · 10−5) der Narkotica werden Ruhe- und Umkehrpotential vermindert. Thiobarbiturate bewirken im Vergleich zu Barbituraten eine se…

Die positiv inotrope Wirkung von Theophyllin, Adrenalin und Strophanthin am Papillarmuskel bei Sch�digung durch Dinitrophenol, Azid, Chinin und Barbi…

1960

Rapid improvement from barbiturate coma by phenytoin

1997

Intraoperative neuroprotective drugs without beneficial effects? Results of the German Registry for Acute Aortic Dissection Type A (GERAADA).

2013

OBJECTIVES: Cerebral protection during acute aortic dissection Type A (AADA) surgery may be affected by perfusion strategies and ischaemic protective drugs. METHODS: We analysed the impact of intraoperative barbiturate, steroid and mannitol use and adjunctive cerebral perfusion (CP), on 30-day mortality and new postoperative mortality-corrected permanent neurological dysfunction (PNDmc) in the German Registry for Acute Aortic Dissection Type A. RESULTS: Two thousand one hundred and thirty-seven AADA patients were registered over a 4-year period. The overall 30-day mortality was 16.9%, and the overall rate of PNDmc was 10.0%. A total of 48% of patients received no neuroprotective drugs (cont…

Cytofluorometric detection of wine lactic acid bacteria: application of malolactic fermentation to the monitoring

2012

Abstract In this study we report for the first time a rapid, efficient and cost-effective method for the enumeration of lactic acid bacteria (LAB) in wine. Indeed, up to now, detection of LAB in wine, especially red wine, was not possible. Wines contain debris that cannot be separated from bacteria using flow cytometry (FCM). Furthermore, the dyes tested in previous reports did not allow an efficient staining of bacteria. Using FCM and a combination of BOX/PI dyes, we were able to count bacteria in wines. The study was performed in wine inoculated with Oenococcus oeni (106 CFU ml−1) stained with either FDA or BOX/PI and analyzed by FCM during the malolactic fermentation (MLF). The analysis …

Barbiturate jaundice

1969

Summary A case of barbital-induced jaundice is described. The patient, a 31-year-old woman, developed generalized skin eruption, mucosal lesions, and fever 2 hr after the ingestion of 2 tablets of a barbital-containing drug (Veramon). She then developed a deep cholestatic jaundice which lasted more than 7 months. During the remission of jaundice, a rechallenge with phenobarbital caused a recurrence of fever and skin eruption, with exacerbation of jaundice.

In vitro free radical scavenging capacity of thyroid hormones and structural analogues.

2001

It was reported that thyroid hormones decreased Cu(2+)-induced low-density lipoprotein (LDL) oxidation in vitro. Here, we investigated free radical scavenging capacities of thyroid hormones (3,5,3'-tri-iodo-L-thyronine (T(3)), thyroxine (T(4)) and 3,3',5'-tri-iodo-L-thyronine (rT(3))) and structural analogues (L-thyronine (T(0)), 3,5,3'tri-iodothyroacetic acid (TA(3)) and 3,5,3',5'-tetra-iodothyroacetic acid (TA(4))), using three different models of free radical generation. T(0), T(3) and TA(3) slowed down production of conjugated diene and thiobarbituric acid-reactive substances during LDL oxidation by 2,2'-azobis-[2-amidinopropane] (water-soluble), whereas rT(3), T(4) and TA(4) had practi…

Suppression of Electrographic Seizures Is Associated with Amelioration of QTc Interval Prolongation in Patients with Traumatic Brain Injury.

2021

Introduction: Disorders in electroencephalography (EEG) are commonly noted in patients with traumatic brain injury (TBI) and may be associated with electrocardiographic disturbances. Electrographic seizures (ESz) are the most common features in these patients. This study aimed to explore the relationship between ESz and possible changes in QTc interval and spatial QRS-T angle both during ESz and after ESz resolution. Methods: Adult patients with TBI were studied. Surface 12-lead ECGs were recorded using a Cardiax device during ESz events and 15 min after their effective suppression using barbiturate infusion. The ESz events were diagnosed using Masimo Root or bispectral index (BIS) devices.…