Search results for "Bioengineering"
showing 10 items of 1963 documents
Nanodiamond Theranostic for Light-Controlled Intracellular Heating and Nanoscale Temperature Sensing
2021
Temperature is an essential parameter in all biological systems, but information about the actual temperature in living cells is limited. Especially, in photothermal therapy, local intracellular temperature changes induce cell death but the local temperature gradients are not known. Highly sensitive nanothermometers would be required to measure and report local temperature changes independent of the intracellular environment, including pH or ions. Fluorescent nanodiamonds (ND) enable temperature sensing at the nanoscale independent of external conditions. Herein, we prepare ND nanothermometers coated with a nanogel shell and the photothermal agent indocyanine green serves as a heat generato…
Toward a virtual reconstruction of an antique three-dimensional marble puzzle
2017
International audience; Abstract | Introduction | Related Work | Acquisition Setup, Proposed Prototype: Calibration and Visibility | Preprocessing of Scanned Three-Dimensional Fragment Data | Processing of Scanned Three-Dimensional Surface Data: Matching | Conclusion and Future Works | Appendices | Acknowledgments | ReferencesAbstract. The reconstruction of broken objects is an important field of research for many applications, such as art restoration, surgery, forensics, and solving puzzles. In archaeology, the reconstruction of broken artifacts is a very time-consuming task due to the handling of fractured objects, which are generally fragile. However, it can now be supported by three-dim…
Model Free Control for muscular force by Functional Electrical Stimulation using pulse width modulation
2016
International audience; Functional Electrical Stimulation (FES) is a useful technique for restoring functions for patients with neurological disorders. Muscle activities can be artificially driven through delivery of electrical pulses to skeletal muscles. Typically, muscles are activated by using constant stimulation train with a fixed parameters (amplitude, frequency and pulse width). In addition, the FES systems do not adapt the parameters stimulation to obtain a desired force response during the rehabilitation session. The purpose of this study is to investigate a real-time FES system for adapting automatically the stimulation parameters (stimulation pulse width) to track a desired force…
Contrôle Optimal appliqué au contrôle de la phase en IRM : simulations et expériences sur fantômes
2017
National audience; IntroductionLes techniques IRM utilisant la phase du signal IRM, à la place ou en complément de l’amplitude, sont de plus en plus nombreuses. Dans ces techniques, la phase est gérée par l’application de gradients. Nous proposons ici de contrôler la phase du signal directement avec des impulsions RF. Pour cela, nous avons utilisé la théorie du contrôle optimal1 et calculé des impulsions RF optimisées pour atteindre des états cibles (dans notre cas, des motifs de phase) préalablement définis. Dans cette étude, une preuve de faisabilité de contrôle de la phase IRM par impulsions RF est présentée au travers de simulations (avec le logiciel ODIN2) ainsi que d’expériences IRM s…
Remote Photoplethysmography Based on Implicit Living Skin Tissue Segmentation
2016
International audience; Region of interest selection is an essential part for remote photoplethysmography (rPPG) algorithms. Most of the time, face detection provided by a supervised learning of physical appearance features coupled with skin detection is used for region of interest selection. However, both methods have several limitations and we propose to implicitly select living skin tissue via their particular pulsatility feature. The input video stream is decomposed into several temporal superpixels from which pulse signals are extracted. Pulsatility measure for each temporal superpixel is then used to merge pulse traces and estimate the photoplethysmogram signal. This allows to select …
Nouvelle tomographie Compton
2009
International audience
Definition of a mutual reference shape based on information theory and active contours
2013
In this paper, we propose to consider the estimation of a reference shape from a set of different segmentation results using both active contours and information theory. The reference shape is then defined as the minimum of a criterion that benefits from both the mutual information and the joint entropy of the input segmentations. This energy criterion is here justified using similarities between information theory quantities and area measures, and presented in a continuous variational framework. This framework brings out some interesting evaluation measures such as the specificity and sensitivity. In order to solve this shape optimization problem, shape derivatives are computed for each te…
Etude de la stabilité de films industriels de PLA et de leur modification de surface pour des applications en tant qu'emballage alimentaire biodégrad…
2017
Poly(lactic acid) (PLA) is a biodegradable and renewable polyester, which is considered as the most promising eco-friendly substitute of conventional plastics. It is mainly used for food packaging applications, but some drawbacks still reduce its applications. On the one hand, its low barrier performance to gases (e.g. O2 and CO2) limits its use for applications requiring low gas transfer, such as modified atmosphere packaging (MAP) or for carbonate beverage packaging. On the other hand, its natural water sensitivity, which contributes to its biodegradation, limits its use for high moisture foods with long shelf life.Other biopolymers such as wheat gluten (WG) can be considered as interesti…
MRI-visible nanoparticles from hydrophobic gadolinium poly(ε-caprolactone) conjugates
2015
International audience; In this work we report on the synthesis of two hydrophobic and degradable gadolinium poly(ε-caprolactone) conjugates and their use for the preparation of MRI-visible nanoparticles intended for diagnosis applications. Advantage has been taken from functional poly(ε-caprolactone)s (PCL) bearing propargyl (PCL-yne) or amine groups (P(CL-co-NH2VL)) to yield conjugates by following two strategies. In a first approach, an azido-chelate of gadolinium (Gd(III)) has been conjugated by CuAAC to PCL-yne to yield a polymeric chelate containing 2.6 wt% of Gd(III). In a second approach, a dianhydride Gd(III)-ligand was reacted with P(CL-co-NH2VL) to yield, after complexation with …
Interactive evolution for cochlear implants fitting
2007
International audience; Cochlear implants are devices that become more and more sophisticated and adapted to the need of patients, but at the same time they become more and more difficult to parameterize. After a deaf patient has been surgically implanted, a specialised medical practitioner has to spend hours during months to precisely fit the implant to the patient. This process is a complex one implying two intertwined tasks: the practitioner has to tune the parameters of the device (optimisation) while the patient's brain needs to adapt to the new data he receives (learning). This paper presents a study that intends to make the implant more adaptable to environment (auditive ecology) and…