Search results for "Bioinformatic"
showing 10 items of 1651 documents
Approche préventive de la qualité des données d'importation dans le contexte de la protéomique clinique
2011
International audience; Dans le domaine biomédical, la protéomique est confrontée à des sources de données de plus en plus nombreuses et à des volumes de données très importants du fait de la multiplication des technologies dites à haut débit. L'hétérogénéité de la provenance des données implique de fait une hétérogénéité dans la représentation et le contenu de ces données. Les données peuvent aussi se révéler incorrectes ce qui engendre des erreurs sur les conclusions des expériences protéomiques. Notre approche a pour objectif de garantir la qualité initiale des données lors de leur importation dans un système d'information dédié à la protéomique. Elle est basée sur le couplage entre des …
CeLL, an agent based model for exploring the spatial influence influence of climate change on Lobesia botrana population dynamics
2016
International audience; The European Grapevine moth (Lobesia botrana) is one of the most noxious vineyard-pests in the European and Mediterranean area. Its larvae feed on grapevine flowers and berries, and usually cause considerable damage, also by facilitating saphrophytic infections to berries.The biology of L. botrana has been investigated since the 80s. A number of studies has tested its physiology and behaviour in experimental conditions (Hurtrel et Thiéry 1999), in field conditions (Stockel et al. 1994), and using mathematical modelling techniques. Whereas the modelling approaches that have been proposed in the literature are hetereogeneus they generally focus on the phenology and pop…
Analysis of headspace of flavour compounds using PTR-ToF Mass Spectrometry: optimisation of acquisition parameters
2011
National audience
Decoding sweet taste from chemical structures
2019
International audience
L'annuaire des Centres de Ressources Biologiques français
2011
International audience
The I3-CRB project and the French biological ressources centers
2010
International audience
Etudes d'objets combinatoires : applications à la bio-informatique
2011
This thesis considers classes of combinatorial objects that model data in bioinformatics. We have studied two methods of mutation of genes within the genome : duplication and inversion. At first,we study the problem of the whole mirror duplication-random lossmodel in terms of pattern avoiding permutations. We prove that the class of permutations obtained with this method after p duplications from the identity is the class of permutations avoiding alternating permutations of length 2p + 1.We also enumerate the number of duplications that are necessary and sufficient to obtain any permutation of length n from the identity. We also suggest two efficient algorithms to reconstruct two different …
GnS-PIPE: an optimized bionformatic pipeline to efficiently assess microbial taxonomic diversity of complex environments using high throughput sequen…
2013
International audience; The rRNA genes (16S, 18S, ITS) are widely used to study microbial communities in soils, as they can be easily amplified from metagenomic DNA. Moreover, the recent development of high-throughput sequencing technologies allows the assessment of millions of sequences from a single metagenomic DNA. Some pipelines are already available (e.g. QIIME or Mothur) to efficiently treat such data. However, the development of bioinformatic tools must now be validated by various biological tests. This was particularly true for key steps to appraise microbial diversity and richness. Here, we present a new pipeline named GnS-PIPE, a software application performing bacterial, archaeal…
GnS-PIPE: an optimized bionformatic pipeline to efficiently assess microbial taxonomic diversity of complex environments using high throughput sequen…
2013
International audience; The rRNA genes (16S, 18S, ITS) are widely used to study microbial communities in soils, as they can be easily amplified from metagenomic DNA. Moreover, the recent development of high-throughput sequencing technologies allows the assessment of millions of sequences from a single metagenomic DNA. Some pipelines are already available (e.g. QIIME or Mothur) to efficiently treat such data. However, the development of bioinformatic tools must now be validated by various biological tests. This was particularly true for key steps to appraise microbial diversity and richness. Here, we present a new pipeline named GnS-PIPE, a software application performing bacterial, archaeal…
Prise en compte de la technologie dans la quantification des biomarqueurs
2016
International audience; Part de la variance technologique dans la quantification des biomarqueurs. Exemple en protéomique avec la technologie MALDI-TOF