Search results for "Bust"
showing 10 items of 1000 documents
Next generation diagnostic algorithm in non-small cell lung cancer predictive molecular pathology: The KWAY Italian multicenter cost evaluation study
2022
Abstract Aims The KWAY project aims to investigate the economic sustainability of the up-front NGS technologies adoption in the analysis of clinically relevant molecular alterations in NSCLC patients. Methods The diagnostic workflow and the related sustained costs of five Italian referral centers were assessed in four different evolving scenarios were analyzed. For each scenario, two alternative testing strategies were evaluated: the Maximized Standard strategy and the Maximized NGS strategy. Results For each center, the robustness of obtained results was verified through a deterministic sensitivity analysis, observing the variation of total costs based on a variation of ±20 % of the input …
Loop seals in circulating fluidized beds – Review and parametric studies using CPFD simulation
2020
Abstract Loop seal is a robust particle recycling technique used in circulating fluidized bed (CFB) reactors. The rate and the location of the loop seal aeration exert a significant impact on the rate of particle circulation (GS). The standpipe balances the cumulative pressure drop across the rest of the CFB by adjusting its particle height or gas-particle slip velocity. Higher fraction of the loop seal aeration naturally flows down to riser. Increased pressure drop in the standpipe results in high rate of particle circulation. Computational-particle-fluid-dynamic (CPFD) code is customized for multiphase flow modelling. The inbuilt tool of “BC connectors” was incorporated to downsize a CFB …
Learning Behavioral Rules from Multi-Agent Simulations for Optimizing Hospital Processes
2021
Hospital processes are getting more and more complex, starting from the creation of therapy plans over intra-hospital transportation up to the coordination of patients and staff members. In this paper, multi-agent simulations will be used to optimize the coordination of different kinds of individuals (like patients and doctors) in a hospital process. But instead of providing results in form of optimized schedules, here, behavioral rules for the different individuals will be learned from the simulations, that can be exploited by the individuals to optimize the overall process. As a proof-of-concept, the approach will be demonstrated in different variants of a hospital optimization scenario, …
The linear saturated decentralized strategy for constrained flow control is asymptotically optimal
2013
We present an algorithm for constrained network flow control in the presence of an unknown demand. Our algorithm is decentralized in the sense that it is implemented by a team of agents, each controlling just the flow on a single arc of the network based only on the buffer levels at the nodes at the extremes of the arc, while ignoring the actions of other agents and the network topology. We prove that our algorithm is also stabilizing and steady-state optimal. Specifically, we show that it asymptotically produces the minimum-norm flow. We finally generalize our algorithm to networks with a linear dynamics and we prove that certain least-square optimality properties still hold.
Guanxi, trust and reward-based crowdfunding success: a Chinese case
2019
Purpose This paper aims to examine different hypotheses concerning the effects of guanxi on the reward-based crowdfunding project fundraising. Specifically, this study provides new insights into how guanxi and guanxi intensity may affect reward-based crowdfunding success and project performance in the Chinese context. Design/methodology/approach The research data including 989 crowdfunding projects were collected from zhongchou.com which is the largest reward-based crowdfunding platform in a one-year period (2014.1-2014.12). The hypotheses are tested by using robust OLS regressions and robust logistic regressions. Robustness check was also conducted to test the validation of the results. F…
Controllable Solid Propellant Rocket Motor Stability: Deep and Rapid Variable Thrust Operations
2008
When flow and combustion processes couple with the acoustic modes of the combustion chamber, the solid rocket motors experience unsteady gas motion and associated thrust oscillation and motor vibration. The operations of the variable nozzle introduce relevant dynamic changes in the chamber flow and combustion. This article proposes a non-linear approach for the analysis of the effects of severe nozzle manoeuvres on the controllable solid rocket motor stability and provides the evidence that the acoustic wave amplitude evolution is influenced by the nozzle manoeuvre severity, shape and direction. The additional complexity in the problem of the combustion stability analysis introduced by the …
RPPanalyzer Toolbox: An improved R package for analysis of reverse phase protein array data
2014
Analysis of large-scale proteomic data sets requires specialized software tools, tailored toward the requirements of individual approaches. Here we introduce an extension of an open-source software solution for analyzing reverse phase protein array (RPPA) data. The R package RPPanalyzer was designed for data preprocessing followed by basic statistical analyses and proteomic data visualization. In this update, we merged relevant data preprocessing steps into a single user-friendly function and included a new method for background noise correction as well as new methods for noise estimation and averaging of replicates to transform data in such a way that they can be used as input for a new t…
Alkylated dibenzothiophenes in pine needles from pulp and paper mill environment
1998
Abstract Concentrations of alkylated dibenzothiophenes (C n DBTs) in pine needles in a recipient area of the emissions from a pulp and paper mill where also waste combustion was done were measured. The concentrations (ng/g dry weight) of C 1 DBTs were in the range of 2 DBTs in the range of 3 DBTs in the range of 3 DBTs] > [C 2 DBTs] > [C 1 DBTs]. The pulp mill could not be shown to be the source of C 1 C 3 DBTs in the pine needles. Other possible sources are situated in the vicinity of the pulp and paper mill. Long-range transport, either, cannot be excluded as a possible source.
Periodic measures and partially hyperbolic homoclinic classes
2019
In this paper, we give a precise meaning to the following fact, and we prove it: $C^1$-open and densely, all the non-hyperbolic ergodic measures generated by a robust cycle are approximated by periodic measures. We apply our technique to the global setting of partially hyperbolic diffeomorphisms with one dimensional center. When both strong stable and unstable foliations are minimal, we get that the closure of the set of ergodic measures is the union of two convex sets corresponding to the two possible $s$-indices; these two convex sets intersect along the closure of the set of non-hyperbolic ergodic measures. That is the case for robustly transitive perturbation of the time one map of a tr…
Tests of Independence Based on Sign and Rank Covariances
2003
In this paper three different concepts of bivariate sign and rank, namely marginal sign and rank, spatial sign and rank and affine equivariant sign and rank, are considered. The aim is to see whether these different sign and rank covariances can be used to construct tests for the hypothesis of independence. In some cases (spatial sign, affine equivariant sign and rank) an additional assumption on the symmetry of marginal distribution is needed. Limiting distributions of test statistics under the null hypothesis as well as under interesting sequences of contiguous alternatives are derived. Asymptotic relative efficiencies with respect to the regular correlation test are calculated and compar…