Search results for "C.1.4"
showing 10 items of 14 documents
Vegetation structure and greenness in Central Africa from Modis multi-temporal data.
2013
African forests within the Congo Basin are generally mapped at regional scale as broad-leaved evergreen forests, with a main distinction between terra-firme and swamp forests types. At the same time, commercial forest inventories, as well as national maps, have highlighted a strong spatial heterogeneity of forest types. A detailed vegetation map generated using consistent methods is needed to inform decision makers about spatial forest organisation and theirs relationships with environmental drivers in the context of global change. We propose a multi-temporal remotely sensed data approach to characterize vegetation types using vegetation index annual profiles. The classifications identified…
A double-negative (IgD−CD27−) B cell population is increased in the peripheral blood of elderly people
2009
The T cell branch of the immune system has been extensively studied in the elderly and it is known that the elderly have impaired immune function, mainly due to the chronic antigenic load that ultimately causes shrinkage of the T cell repertoire and filling of the immunologic space with memory T cells. In the present paper, we describe the IgD(-)CD27(-) double-negative B cell population which (as we have recently described) is higher in the elderly. Most of these cells were IgG(+). Evaluation of the telomere length and expression of the ABCB1 transporter and anti-apoptotic molecule, Bcl2, shows that they have the markers of memory B cells. We also show that these cells do not act as antigen…
Diagnostic genetic screening for assisted reproductive technologies patients with macrozoospermia
2017
International audience; Macrozoospermia is characterized by a high proportion of abnormal spermatozoa with enlarged heads. So far, it has been associated with mutations only in the Aurora Kinase C gene (AURKC) in some cases. Although many publications have reported failure to conceive in couples with macrozoospermia, a few others have described successful pregnancies, thus raising questions as to whether ICSI and AURKC genetic screening should be recommended in all patients with macrozoospermia. First, we report on two monozygotic twins presenting macrozoospermia for whom the genetic status was explored (Aurora Kinase C sequencing) and whole semen and gradient-selected spermatozoa were anal…
B cells in the aged: CD27, CD5, and CD40 expression.
2003
Ageing is characterized by numerous changes in lymphocyte subpopulations. In the present paper we have focused on B cells carrying the surface markers CD27, CD5 and CD40. CD27 is considered a marker of primed (memory) cells and its engagement promotes the differentiation of memory B cells into plasma cells. CD5 is expressed on B1 cells, which are considered to be responsible for T cell-independent antibody production other than autoantibodies. The CD40 molecule binds CD40L (CD154) and is necessary for T-dependent antibody responses. Here we show that the absolute number of CD5+ and CD40+ B cells is decreased in the elderly, while CD27+ B lymphocytes only marginally decrease in centenarians.…
Atherosclerosis as an inflammatory disease.
2011
In many ways, atherosclerosis is a chronic inflammatory disorder and this issue is confirmed by recent investigations of that have focused on inflammation, providing new insight into mechanisms of disease. Several recent studies have addressed the role of chemokines in leukocyte accumulation in atherosclerosis, extending our knowledge and understanding of the complex and cell type-specific functions of chemokines in atherosclerosis. Activated T-lymphocytes within the atherosclerotic vessel wall express the CD40 ligand surface molecule, known to play a major role in several immunological pathways. In addition to activated T-lymphocytes, functional CD40 and CD40L are coexpressed by human vasc…
Unveiling the strong interaction among hadrons at the LHC
2020
One of the key challenges for nuclear physics today is to understand from first principles the effective interaction between hadrons with different quark content. First successes have been achieved using techniques that solve the dynamics of quarks and gluons on discrete space-time lattices1,2. Experimentally, the dynamics of the strong interaction have been studied by scattering hadrons off each other. Such scattering experiments are difficult or impossible for unstable hadrons3–6 and so high-quality measurements exist only for hadrons containing up and down quarks7. Here we demonstrate that measuring correlations in the momentum space between hadron pairs8–12 produced in ultrarelativistic…
Unified System for Processing Real and Simulated Data in the ATLAS Experiment
2015
The physics goals of the next Large Hadron Collider run include high precision tests of the Standard Model and searches for new physics. These goals require detailed comparison of data with computational models simulating the expected data behavior. To highlight the role which modeling and simulation plays in future scientific discovery, we report on use cases and experience with a unified system built to process both real and simulated data of growing volume and variety.
Agroecological engineering
2015
Earth has recently entered the new era of the Anthropocene, during which the rise of human activities are impacting for the first time ecosystems and climate on the global scale. Since the 1960s the green revolution has improved food production in quantity using industrially-designed agriculture, which has led to global pollution by pesticides and losses of food quality, biodiversity and soil carbon. As a consequence there is a need to implement agroecological practices in order to produce food safely and in a sustainable way. This virtual issue presents principles and applications of agroecological engineering, exemplified in 19 selected review articles from the journal Agronomy for Sustai…
1,4 - dihidropiridīna atvasinājumu (AV-153-sāļu) mijiedarbības izpēte pret c-Myc antiparalēlo kvadrupleksu, izmantojot UV/redzamo spektroskopiju
2020
Pedējos gados ievērojami pastiprinājusies uzmanība pret DNS guanīna kvadrupleksiem un to lomu onkoģenēzē. c-Myc proto-onkogēna pastiprināta ekspresija ir saistīta ar dažādiem cilvēka audzējiem, ka arī ar slikto prognozi. Līdz ar to DNS guanīna kvadrupleksu veidošana un stabilizācija C-myc promoter reģionos ir kritiska c-Myc trankripcijas inhibēšanai, tāpēc pēdējos gados aktīvi tiek meklēti savienojumi, kuri var stabilizēt G-kvadrupleksu struktūras un inhibēt c-Myc gēna ekspresiju. Šī pētījuma darba mērķis bija izpētīt 1,4-dihidropiridīna atvasinājumu (AV-153 sāļu un to analoga AV-154-Na sāls) spēju mijiedarboties ar antiparalēlo c-myc kvadrupleksu, kā arī spēju mijiedarboties ar vienpavadie…
In situ Mössbauer spectroscopy: Evidence for green rust (fougerite) in a gleysol and its mineralogical transformations with time and depth
2005
Abstract A miniaturized Mossbauer spectrometer, adapted to the Earth’s conditions from the instrument developed for Mars space missions, has been used for the first time to study in situ variations with depth and transformations with time of iron minerals in a gleysol. The instrument is set into a PVC tube and can be moved up and down precisely (±1 mm) at the desired depth. Mossbauer spectra were obtained from 15 to 106 cm depth and repeated exactly at the same point at different times to follow mineralogical transformations with time. X-ray diffraction (XRD) and selective extraction techniques were performed on soil samples. The piezometric level of the water table was measured and the com…