Search results for "C.M.M."
showing 10 items of 1066 documents
Tissue invasiveness and non-acidic pH in human candidiasis correlate with "in vivo" expression by Candida albicans of the carbohydrate epitope recogn…
2004
Background: The morphogenetic conversion between yeast and hyphal growth forms appears to be crucial in the pathogenesis of invasive candidiasis, and can be regulated by environmental signals such as extracellular pH. Aims: To characterise the epitope recognised by monoclonal antibody 1H4, and to evaluate the expression of its corresponding epitope in Candida albicans cells under different conditions of pH and temperature, and “in vivo”, in tissue samples from patients with human candidiasis. Methods: Monoclonal antibody 1H4 was generated against the 58 kDa cell wall mannoprotein of C albicans (mp58), and was further characterised by immunoblot analysis, periodate treatment of the antigenic…
Probing Sizes and Shapes of Nobelium Isotopes by Laser Spectroscopy
2018
Until recently, ground-state nuclear moments of the heaviest nuclei could only be inferred from nuclear spectroscopy, where model assumptions are required. Laser spectroscopy in combination with modern atomic structure calculations is now able to probe these moments directly, in a comprehensive and nuclear-model-independent way. Here we report on unique access to the differential mean-square charge radii of ^{252,253,254}No, and therefore to changes in nuclear size and shape. State-of-the-art nuclear density functional calculations describe well the changes in nuclear charge radii in the region of the heavy actinides, indicating an appreciable central depression in the deformed proton densi…
The operating cost of an anaerobic membrane bioreactor (AnMBR) treating sulphate-rich urban wastewater
2014
The objective of this study was to evaluate the operating cost of an anaerobic membrane bioreactor (AnMBR) treating sulphate-rich urban wastewater (UWW) at ambient temperature (ranging from 17 to 33 degrees C). To this aim, energy consumption, methane production, and sludge handling and recycling to land were evaluated. The results revealed that optimising specific gas demand with respect to permeate volume (SGDp) and sludge retention time (for given ambient temperature conditions) is essential to maximise energy savings (minimum energy demand: 0.07 kW h m(-3)). Moreover, low/moderate sludge productions were obtained (minimum value: 0.16 kg TSS kg(-1) CODRemoved), which further enhanced the…
Model-based automatic tuning of a filtration control system for submerged anaerobic membrane bioreactors (AnMBR)
2014
This paper describes a model-based method to optimise filtration in submerged AnMBRs. The method is applied to an advanced knowledge-based control system and considers three statistical methods: (1) sensitivity analysis (Morris screening method) to identify an input subset for the advanced controller; (2) Monte Carlo method (trajectory-based random sampling) to find suitable initial values for the control inputs; and (3) optimisation algorithm (performing as a supervisory controller) to re-calibrate these control inputs in order to minimise plant operating costs. The model-based supervisory controller proposed allowed filtration to be optimised with low computational demands (about 5min). E…
Resource recovery from sulphate-rich sewage through an innovative anaerobic-based water resource recovery facility (WRRF)
2018
[EN] This research work proposes an innovative water resource recovery facility (WRRF) for the recovery of energy, nutrients and reclaimed water from sewage, which represents a promising approach towards enhanced circular economy scenarios. To this aim, anaerobic technology, microalgae cultivation, and membrane technology were combined in a dedicated platform. The proposed platform produces a high-quality solid- and coliform-free effluent that can be directly discharged to receiving water bodies identified as sensitive areas. Specifically, the content of organic matter, nitrogen and phosphorus in the effluent was 45 mg COD.L-1 , 14.9 mg N.L-1 and 0.5 mg P.L-1 , respectively. Harvested solar…
Factors that affect the permeability of commercial hollow-fibre membranes in a submerged anaerobic MBR (HF-SAnMBR) system
2013
A demonstration plant with two commercial HF ultrafiltration membrane modules (PURON (R), Koch Membrane Systems, PUR-PSH31) was operated with urban wastewater. The effect of the main operating variables on membrane performance at sub-critical and supracritical filtration conditions was tested. The physical operating variables that affected membrane performance most were gas sparging intensity and back-flush (BF) frequency. Indeed, low gas sparging intensities (around 0.23 Nm(3) h(-1) m(-2)) and low BF frequencies (30s back-flush for every 10 basic filtration relaxation cycles) were enough to enable membranes to be operated sub-critically even when levels of mixed liquor total solids were hi…
Economic and environmental sustainability of an AnMBR treating urban wastewater and organic fraction of municipal solid waste
2016
[EN] The objective of this study was to evaluate the economic and environmental sustainability of a sub- merged anaerobic membrane bioreactor (AnMBR) treating urban wastewater (UWW) and organic fraction of municipal solid waste (OFMSW) at ambient temperature in mild/hot climates. To this aim, power requirements, energy recovery from methane (biogas methane and methane dissolved in the effluent), consumption of reagents for membrane cleaning, and sludge handling (polyelectrolyte and energy consumption) and disposal (farmland, landfilling and incineration) were evaluated within different operating scenarios. Results showed that, for the operating conditions considered in this study, AnMBR tec…
Selecting the most suitable microalgae species to treat the effluent from an anaerobic membrane bioreactor.
2018
[EN] Conventional treatments for nutrient removal in wastewater are shifting to Anaerobic Membrane Bioreactors, which produce a high-quality effluent with minimum sludge production. The effluent resulting contains high nitrogen and phosphorus load that can be eliminated by microalgae culture. The aim of this study is to evaluate the ammonium and phosphorus removal rate of different microalgae species in the effluent of an anaerobic treatment. For that, 4 different microalgae species have been tested (Chlamydomonas reinhardtii, Scenedesmus obliquus, Chlorella vulgaris and Monoraphidium braunii) in batch monoculture and mixed conditions. Results indicate that all species are able to eliminate…
Micropollutants removal in an anaerobic membrane bioreactor and in an aerobic conventional treatment plant
2012
The paper expresses an attempt to tackle the problem due to the presence of micropollutants in wastewater which may be able to disrupt the endocrine system of some organisms. These kinds of compounds are ubiquitously present in municipal wastewater treatment plant (WWTP) effluents. The aim of this paper is to compare the fate of the alkylphenols-APs (4-(tert-octyl)) phenol, t-nonylphenol and 4-p-nonylphenol and the hormones (estrone, 17ß-estradiol and 17¿-ethinylestradiol) in a submerged anaerobic membrane bioreactor (SAMBR) pilot plant and in a conventional activated sludge wastewater treatment plant (CTP). The obtained results are also compared with the results obtained in a previous stud…
Macrophages Escape Inhibition of Major Histocompatibility Complex Class I-Dependent Antigen Presentation by Cytomegalovirus
2000
ABSTRACTThe mouse cytomegalovirus (MCMV)m152- andm06-encoded glycoproteins gp40 and gp48, respectively, independently downregulate major histocompatibility complex (MHC) class I surface expression during the course of productive MCMV infection in fibroblasts. As a result, presentation of an immediate-early protein pp89-derived nonapeptide toH-2Ld-restricted CD8+cytotoxic T cells is completely prevented in fibroblasts. Here we demonstrate that MCMV-infected primary bone marrow macrophages and the macrophage cell line J774 constitutively present pp89 peptides during permissive MCMV infection to cytotoxic T lymphocytes (CTL). In contrast to fibroblasts, expression of them152andm06genes in macr…