Search results for "C.M.M."

showing 10 items of 1066 documents

Screening individual ability to perform descriptive analysis of food products : basic statements and application to a camembert cheese descriptive pa…

1995

A battery of sensory tests is proposed to select potential descriptive panelists. This set of tests is flavor specific. Several abilities are examined: odor and taste recognition, odor memory, discrimination and descriptive capacities. A detailed example of such a battery to select a Camembert cheese descriptive panel is given. The objectives of each test are discussed. Stimuli are chosen to be consistent with the sensory properties which can be perceived in cheese. Score distributions demonstrate the discrimination among candidates for each test. Globally, results show the difficulty to find 20 panelists amongst about a hundred with good scores on each test. The panel leader has to choose …

2. Zero hungerCommunicationDescriptive statisticsbusiness.industry[SDV]Life Sciences [q-bio]05 social sciences04 agricultural and veterinary sciencesCamembert cheese040401 food science050105 experimental psychologySensory SystemsTest (assessment)[SDV] Life Sciences [q-bio]0404 agricultural biotechnologySensory testsFood productsStatistics0501 psychology and cognitive sciencesMISE AU POINTSet (psychology)PsychologybusinessComputingMilieux_MISCELLANEOUSFood Science
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Magnetic dichroism in angle-resolved hard x-ray photoemission from buried layers

2011

This work reports the measurement of magnetic dichroism in angular-resolved photoemission from in-plane magnetized buried thin films. The high bulk sensitivity of hard x-ray photoelectron spectroscopy (HAXPES) in combination with circularly polarized radiation enables the investigation of the magnetic properties of buried layers. HAXPES experiments with an excitation energy of 8 keV were performed on exchange-biased magnetic layers covered by thin oxide films. Two types of structures were investigated with the IrMn exchange-biasing layer either above or below the ferromagnetic layer: one with a CoFe layer on top and another with a Co${}_{2}$FeAl layer buried beneath the IrMn layer. A pronou…

420Materials scienceMagnetic momentCondensed matter physicsAnalytical chemistryDichroismengineering.materialCondensed Matter PhysicsHeusler compoundElectronic Optical and Magnetic Materialscircularly polarized x-raysCondensed Matter::Materials ScienceX-ray photoelectron spectroscopyFerromagnetismX-ray magnetic circular dichroismmagnetic dichroismangular-resolved hard x-ray photoemissionengineeringThin filmExcitationPhysical Review B
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Search for a Dark Leptophilic Scalar in e(+) e(-) Collisions

2020

Many scenarios of physics beyond the standard model predict the existence of new gauge singlets, which might be substantially lighter than the weak scale. The experimental constraints on additional scalars with masses in the MeV to GeV range could be significantly weakened if they interact predominantly with leptons rather than quarks. At an e+e- collider, such a leptophilic scalar (φL) would be produced predominantly through radiation from a τ lepton. We report herein a search for e+e-→τ+τ-φL, φL→ℓ+ℓ- (ℓ=e, μ) using data collected by the BABAR experiment at SLAC. No significant signal is observed, and we set limits on the φL coupling to leptons in the range 0.04<mφL<7.0 GeV. These bounds s…

:Kjerne- og elementærpartikkelfysikk: 431 [VDP]Electron–positron annihilationPhysics beyond the Standard ModelGeneral Physics and Astronomy01 natural sciencesElementary particlecurrent: constraintE+e- collider[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]HEP BaBarMathematical physicsPhysicstau: pair productionnew physics: search forSettore FIS/01 - Fisica Sperimentalescale: electroweak interactionelectron positron: colliding beamsModel estàndard (Física nuclear)Standard model (Nuclear physics)Monte Carlo method:Nuclear and elementary particle physics: 431 [VDP]The standard modelConfidence levelPEP-IIAnomalous magnetic momentleptonic decayScalar (mathematics)lepton: couplinganomalycoupling constant: upper limitelectron positron: annihilationNOMagnetic momentBABAR experimentlepton: coupling: high0103 physical sciencesParameter spaceBaBar; PEP-II; Rare decays;singlet: gauge010306 general physicsMètode de Montecarlomuon: magnetic momentHigh Energy Physics::PhenomenologyRare decaysSLAC PEP StorRare decay[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]BaBarElementary Particles and FieldsHigh Energy Physics::ExperimentLeptonexperimental results
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Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo

2021

Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically, mainly due to the inhibitor specificity, toxicity, and drug interactions. Here, we reported that three polyoxypregnanes (POPs) as the most abundant constituents of Marsdenia tenacissima (M. tenacissima) were novel ABCB1-modulatory pro-drugs, which underwent intestinal microbiota-mediated biotransformation in vivo to generate active metabolites. The metabolites at non-toxic concentrations restored chemosensitivity in ABCB1-overexpressing cancer cells v…

ABCC1 ATP binding cassette subfamily C member 1IC50 half maximal inhibitory concentrationMultidrug resistancePharmacologyNADPH reduced nicotinamide adenine dinucleotide phosphateF bioavailabilitychemistry.chemical_compoundPCR polymerase chain reaction0302 clinical medicineMDR multidrug resistanceECL electrochemiluminescencet1/2 elimination half-lifeLC–MS liquid chromatography coupled with mass spectrometryN.D. not detectedGeneral Pharmacology Toxicology and PharmaceuticsBBB blood–brain barriermedia_commonATF3 activating transcription factor 30303 health sciencesChemistryABC ATP-binding cassetteNMPA National Medical Products AdministrationPXR pregnane X receptorSDS-PAGE sodium dodecyl sulfate-polyacrylamide gel electrophoresisHBSS Hankʹs balanced salt solutionABCB1Combination chemotherapyProdrugMarsdenia tenacissimaCmax peak concentrationPaclitaxelGAPDH glyceraldehyde-3-phosphate dehydrogenase030220 oncology & carcinogenesisBHI brain heart infusionOriginal ArticleAUC0–∞ area under plasma concentration vs. time curveMRT mean residence timeDrugmedia_common.quotation_subjectRM1-950Vd volume of distributionABCB1 ATP binding cassette subfamily B member 1UIC-2 mouse monoclonal ABCB1 antibodyABCG2 ATP binding cassette subfamily G member 2Combination chemotherapyCYP cytochrome P450 isozymePI propidium iodideTEER transepithelial electrical resistance03 medical and health sciencesPBS phosphate buffer salineFBS fetal bovine serumDox doxorubicinIn vivoPOP polyoxypregnanemedicine030304 developmental biologyEVOM epithelial tissue voltohmmeterTmax time for peak concentrationCancerLBE lowest binding energyPE phycoerythrinmedicine.diseaseMultiple drug resistancePolyoxypregnanePapp apparent permeabilityN.A. not applicableCancer cellH&E hematoxylin and eosinMDR1a multidrug resistance protein 1aTherapeutics. PharmacologyqPCR quantitative PCRM. tenacissima Marsdenia tenacissimaCL clearanceSD standard derivationActa Pharmaceutica Sinica B
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Modeling the anaerobic treatment of sulfate rich urban wastewater. Application to AnMBR technology

2020

[EN] Although anaerobic membrane bioreactors (AnMBR) are a core technology in the transition of urban wastewater (UWW) treatment towards a circular economy, the transition is being held back by a number of bottlenecks. The dissolved methane released from the effluent, the need to remove nutrients (ideally by recovery), or the energy lost by the competition between methanogenic and sulfate-reducing bacteria (SRB) for the biodegradable COD have been identified as the main issues to be addressed before AnMBR becomes widespread. Mathematical modeling of this technology can be used to obtain further insights into these bottlenecks plus other valuable information for design, simulation and contro…

AcidogenesisAnaerobic membrane bioreactorEnvironmental EngineeringMethanogenesis0208 environmental biotechnology02 engineering and technology010501 environmental sciencesWastewater01 natural sciencesWaste Disposal FluidBioreactorsBNRM2BioreactorAnaerobiosisWaste Management and DisposalEffluentTECNOLOGIA DEL MEDIO AMBIENTE0105 earth and related environmental sciencesWater Science and TechnologyCivil and Structural EngineeringSulfate-rich urban wastewaterSulfatesEcological ModelingModelingPulp and paper industryPollution020801 environmental engineeringAnaerobic digestionPilot plantWastewaterAcetogenesisEnvironmental scienceMethane
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Magnetic properties of Co2Mn1−xFexSi Heusler alloys

2006

Co2Mn1−xFexSi Heusler alloys with Fe concentration x = 0–0.4 as prepared by arc melting show a L21 long range order for all Fe concentrations. Magnetic properties of Co2Mn1−xFexSi Heusler alloys were investigated by magnetometry and circular magnetic dichroism. The magnetization of the Fe doped Heusler alloys is in agreement with the Slater–Pauling values expected for half-metallic ferromagnets. Element specific magnetic moments as determined by x-ray absorption using the total electron yield method are in disagreement with theoretical predictions for x = 0 but approach the predicted values as the Fe concentration increases. Surprisingly small Fe concentration increases the magnetic moments…

Acoustics and UltrasonicsCondensed matter physicsMagnetic momentMagnetic circular dichroismChemistryMagnetometerElectronDichroismCondensed Matter PhysicsSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialslaw.inventionMagnetizationFerromagnetismlawCircular magnetic dichroismJournal of Physics D: Applied Physics
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Off-stoichiometry in Co2FeSi thin films sputtered from stoichiometric targets revealed by nuclear magnetic resonance

2009

Co2FeSi is predicted to be a half-metallic ferromagnet with an extraordinary high magnetic moment and Curie temperature. However, a low tunnel magneto-resistance ratio, a lower spin polarization and a lower magnetic moment were experimentally observed in thin film samples. Consequently, thin Co2FeSi films of different groups were studied using spin-echo nuclear magnetic resonance (NMR). NMR probes the local hyperfine fields of the active atoms, which strongly depend on the local environment. NMR is thus able to reveal the next neighbouring shells of the Co-59 nuclei in the Co2FeSi thin films. As expected, our NMR study shows the main resonance line corresponding to Co-59 nuclei in the L2(1)…

Acoustics and UltrasonicsMagnetic momentCondensed matter physicsSpin polarizationChemistryResonanceCondensed Matter PhysicsFerromagnetic resonanceSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCondensed Matter::Materials ScienceNuclear magnetic resonanceSpin echoCurie temperatureCondensed Matter::Strongly Correlated ElectronsThin filmHyperfine structureJournal of Physics D: Applied Physics
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High spin polarization in Co2CrAl–Cr superlattice

2009

The electronic structure, magnetic properties and interface effects in Co2CrAl?Cr superstructures have been investigated by the use of first principle calculations. The results show that at the interface, a large magnetic moment and a high spin polarization can be induced by a strong ferromagnetic exchange interaction at the Cr?Co interface. However, at the CrAl?Cr interface, both the magnetic moment and the spin polarization of the Cr atoms are decreased due to a Cr?Cr antiferromagnetic interaction. It can also be found that the interface effect is only a short range effect. So, high spin polarization in Co2CrAl?Cr superlattice can be obtained. Based on this theoretical analysis, a large g…

Acoustics and UltrasonicsSpin polarizationCondensed matter physicsMagnetic momentMagnetoresistanceChemistryMagnetismSuperlatticeGiant magnetoresistanceCondensed Matter PhysicsSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCondensed Matter::Materials ScienceFerromagnetismAntiferromagnetismCondensed Matter::Strongly Correlated ElectronsComputer Science::DatabasesJournal of Physics D: Applied Physics
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The sustainable synthesis of levetiracetam by an enzymatic dynamic kinetic resolution and an ex-cell anodic oxidation

2021

Levetiracetam is an active pharmaceutical ingredient widely used to treat epilepsy. We describe a new synthesis of levetiracetam by a dynamic kinetic resolution and a ruthenium-catalysed ex-cell anodic oxidation. For the enzymatic resolution, we tailored a high throughput screening method to identify Comamonas testosteroni nitrile hydratase variants with high (S)-selectivity and activity. Racemic nitrile was applied in a fed-batch reaction and was hydrated to (S)-(pyrrolidine-1-yl)butaneamide. For the subsequent oxidation to levetiracetam, we developed a ligand-free ruthenium-catalysed method at a low catalyst loading. The oxidant was electrochemically generated in 86% yield. This route pro…

Active ingredientbiologyNitrile010405 organic chemistry010402 general chemistrybiology.organism_classification01 natural sciencesPollutionCombinatorial chemistry0104 chemical sciencesKinetic resolutionCatalysischemistry.chemical_compoundchemistryNitrile hydrataseYield (chemistry)medicineEnvironmental ChemistryComamonas testosteroniLevetiracetammedicine.drugGreen Chemistry
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Immersive Versus Non-immersive Experience: Exploring the Feasibility of Memory Assessment Through 360° Technology

2019

Episodic memory is essential to effectively perform a number of daily activities, as it enables individuals to consciously recall experiences within their spatial and temporal environments. Virtual Reality (VR) serves as an efficacious instrument to assess cognitive functions like attention and memory. Previous studies have adopted computer-simulated VR to assess memory, which realized greater benefits compared to traditional procedures (paper and pencil). One of the most recent trends of immersive VR experiences is the 360° technology. In order to evaluate its capabilities, this study aims to compare memory performance through two tasks: immersive task and non-immersive task. These tasks d…

Activities of daily livinglcsh:BF1-990360° camera; case-comparison; episodic memory; memory assessment; panorama technologymemory assessmentVirtual realityMemory performance050105 experimental psychologyTask (project management)03 medical and health sciences0302 clinical medicineHuman–computer interactionPsychologySettore M-PSI/01 - PSICOLOGIA GENERALE0501 psychology and cognitive sciencesEpisodic memoryGeneral PsychologyOriginal ResearchRecall05 social sciencesCase comparisonCognitionepisodic memorypanorama technology360° cameralcsh:Psychologycase-comparisonPsychology030217 neurology & neurosurgery
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