Search results for "CCC"
showing 10 items of 21 documents
Influenza della concentrazione iodica dei mezzi di contrasto sulla caratterizzazione della placca aterosclerotica coronarica valutata mediante TC Mul…
2010
Studying students ́satisfaction at music schools in the Valencian Region
2017
[EN] Satisfaction is a key construct but complex to be measured. Within the cultural context and from the discipline of marketing, satisfaction consists of assessing some experiences without considering consumers ́ expectations. From this approach, this paper deals with an empirical research aiming at analyzing satisfaction among students of music conservatoires and schools. The research, qualitative and quantitative in nature, allowed to know users ́ assessment of different variables: studies, teaching staff, information technologies, premises and administration procedures. To do so, a self-administered survey was conducted using a structured questionnaire. Univariate and multivariate anal…
Expression of a Truncated Yeast Ccc1 Vacuolar Transporter Increases the Accumulation of Endogenous Iron
2021
Iron is an essential micronutrient for all eukaryotic organisms because it participates as a redox cofactor in multiple metabolic processes. Iron bioavailability is highly restricted due to the low solubility of its oxidized form, frequently leading to iron deficiency anemia. The baker’s yeast Saccharomyces cerevisiae is used as a model organism for iron homeostasis studies, but also as a food supplement and fermentative microorganism in the food industry. Yeast cells use the vacuolar Ccc1 transporter to detoxify and store excess iron in the vacuoles. Here, we modulate CCC1 expression and properties to increase iron extraction from the environment. We show that constitutive expression of fu…
p8 (candidate of metasiasis 1) drives ER-stress/autophagy/apoptosis axis induced by the synthetic cannabinoid WIN in HCC cells.
2010
Background: Today, evidence is emerging for the role of autophagy in the regulation of life and death of tumour cells and its relationship with ER-stress signaling. Our previous results demonstrated that hepatoma HepG2 cells are sensitive to apoptotic effects induced by WIN, a synthetic cannabinoid, which acts through a mechanism involving the reduction in the levels of some survival factors and the activation of pro-apoptotic ones. Since WIN effects were observed after 36−48 hours of treatment, we investigated the possible activation of ER-stress and autophagic process in the first hours of WIN treatment focusing our attention on p8, a factor whose expression is upregulated in response to …
The Epochal Paradigm Shift in Italian Accounting: from a 'Stock' to a 'Flow' Approach
2012
This paper attempts to outline the important shift that Italy faced at the beginning of the XX century in the accounting theory field. We refer in particular to the new approach that saw the 'flow' as main category to be explored instead of the old approach that saw the 'stock' as main object to be investigated.
Il Codex DCCCIX (DCCCXIII) della Biblioteca Capitolare di Verona: «prima trascrizione delle Istituzioni di Gaio» o «copia del tutto inservibile»?
2016
Partendo da una considerazione critica della tesi avanzata da Briguglio nel libro intitolato "La prima trascrizione delle Istituzioni di Gaio. Il Codex DCCCIX (DCCCXIII) Gaii Institutionum Libri della Biblioteca Capitolare di Verona" (2013), si contesta l'idea che la trascrizione parziale delle Istituzioni di Gaio ancor oggi custodita nella Biblioteca Capitolare di Verona (Codex DCCCIX) sia la prima versione in bella copia dei lavori di trascrizione del palinsesto gaiano (Verona, Biblioteca Capitolare, Codex XVI. Un esame più completo del Codex DCCCIX confrontato con le trascrizioni complete conservate nella Staatsbibliothek zu Berlin (Ms. lat. Fol. 308), infatti, dimostra che tale tesi non…
Le prime trascrizioni del palinsesto di Gaio e il presunto «mistero» delle schede veronesi (BCapVr, Cod. DCCCIX)
2014
This paper addresses the question of the origin of the partial transcription of Gaius’ palimpsest still preserved in the Capitular Library of Verona (BCapVr, Cod. DCCCIX) and allows to solve the pretended «mystery» about its presence in this library. A comparison with the fair copy (Reinschrift) of the transcription belonging to the Berlin State Library – Prussian Cultural Heritage (SBB-PK, Ms. lat. fol. 308, K. 1, Konv. 1) shows that the Cod. DCCCIX of the Capitular Library can not be regarded as a forgotten copy or a gift. Similarly, the idea that the manuscript was the first fair copy of the transcription works is not plausible. Anyway, a neglected information provided by one of the Prus…
Monticchio Lakes
2020
The crater lakes are a natural hazard for the population living near them because they can generate liminic explosions, like as the disaster of Nyos lake (Cameroon 1986), in which 1476 people and thousands of animals died. Crater lakes are able to store magmatic and hydrothermal gases and solubilising them into the water. An overpressure of the dissolved gases can generate a limnic eruption. Italy is characterised by an intense volcanic and seismic activity. Evidences of this past volcanism are the numerous crater lakes in Lazio and Campania. The most famous are Bolsena lakes, Vico, Bracciano, Monticchio lakes, Mezzano, Martignano, Albano, Nemi, Averno. The Monticchio lakes (Piccolo Lake (L…
Cambiamenti climatici e diritti umani. Il paradigma della Giustizia climatica e il ruolo delle climate litigations per la protezione dei diritti uman…
2021
In che misura i sempre più diffusi, pervasivi e drammatici impatti dei cambiamenti climatici, che interessano con geometrie variabili tutte le latitudini e longitudini del globo, mettono a rischio la tenuta del sistema dei diritti umani universalmente riconosciuti? La ricerca si pone l'obiettivo di rispondere a tale quesito ragionando su quali sfide essi pongano e su quali siano, nell'attuale panorama, gli strumenti giuridici utili a garantire la piena tutela dei diritti fondamentali nel nuovo contesto clima- alterato. La fondatezza e l’attendibilità delle ricerche scientifiche che avvalorano l’esistenza del cambiamento climatico antropogenico si pongono come presupposto fattuale dell'inter…
Korkean käytettävyyden tekniikoiden hyödyntäminen tehohoidon ja anestesiologian tietojärjestelmissä
2016
Kyselytutkimuksella selvitettiin sitä, onko korkean käytettävyyden teknologioista hyötyä teho- ja anestesiologian tietojärjestelmissä. Erityisesti tutkittiin sitä, vaarantuuko potilaiden turvallisuus tietojärjestelmien avainhenkilöiden mielestä käyttökatkossa, ja jos vaarantuu, niin miten ja millaisia vaaratilanteita syntyy. Lisäksi selvitettiin sitä, kokevatko pääkäyttäjät ja ylläpitäjät nykyiset varajärjestelyt käyttökatkojen osalta riittävinä. Tutkimus selvitti myös teknisiä vaihtoehtoja saatavuuden nostamiseksi ja arvioi niiden kustannuksia ja hyötyjä. Tutkimus osoitti, että vastaajat kokivat nykytilanteen tietojärjestelmän käyttökatkojen osalta tyypillisesti hyvänä. Oli kuitenkin tunni…