Search results for "CHIP"

Autochthonous organic matter promotes DNRA and suppresses N2O production in sediments of the coastal Baltic Sea

2021

Coastal environments are nitrogen (N) removal hot spots, which regulate the amount of land-derived N reaching the open sea. However, mixing between freshwater and seawater creates gradients of inorganic N and bioavailable organic matter, which affect N cycling. In this study, we compare nitrate reduction processes between estuary and offshore archipelago environments in the coastal Baltic Sea. Denitrification rates were similar in both environments, despite lower nitrate and carbon concentrations in the offshore archipelago. However, DNRA (dissimilatory nitrate reduction to ammonium) rates were higher at the offshore archipelago stations, with a higher proportion of autochthonous carbon. Th…

A new set of DNA macrochips for the yeast Saccharomyces cerevisiae: features and uses

2004

The yeast Saccharomyces cerevisiae has been widely used for the implementation of DNA chip technologies. For this reason and due to the extensive use of this organism for basic and applied studies, yeast DNA chips are being used by many laboratories for expression or genomic analyses. While membrane arrays (macroarrays) offer several advantages, for many laboratories they are not affordable. Here we report that a cluster of four Spanish molecular-biology yeast laboratories, with relatively small budgets, have developed a complete set of probes for the genome of S. cerevisiae. These have been used to produce a new type of macroarray on a nylon surface. The macroarrays have been evaluated and…

The “Seili-index” For The Prediction of Chlorophyll-α Levels In The Archipelago Sea of The Northern Baltic Sea, Southwest Finland

2021

AbstractTo build a forecasting tool for the state of eutrophication in the Archipelago Sea, we fitted a Generalized Additive Mixed Model (GAMM) to marine environmental monitoring data, which were collected over the years 2011–2019 by an automated profiling buoy at the Seili ODAS-station. The resulting “Seili-index” can be used to predict the chlorophyll-α (chl-a) concentration in the seawater a number of days ahead by using the temperature forecast as a covariate. An array of test predictions with two separate models on the 2019 data set showed that the index is adept at predicting the amount of chl-a especially in the upper water layer. The visualization with 10 days of chl-a level predict…

Norway-Russia disaster diplomacy for Svalbard

2020

Abstract The Arctic is frequently framed as a region of disaster and conflict, as well as of opportunity and cooperation. Disaster diplomacy is one approach for examining how dealing with disasters might or might not affect conflict and cooperation, yet little work on Arctic disaster diplomacy has been completed, especially regarding specific bilateral relations. This paper contributes to filling in this gap by focusing on the post-USSR era to provide the first examination of the prospects and relevance of Norway-Russia disaster-related interaction for the Svalbard archipelago. As a discussion paper focusing on one case study, Norway-Russia disaster diplomacy is analysed in the context of S…

Functional Near Infrared Spectroscopy System Validation for Simultaneous EEG-FNIRS Measurements

2019

Functional near-infrared spectroscopy (fNIRS) applied to brain monitoring has been gaining increasing relevance in the last years due to its not invasive nature and the capability to work in combination with other well–known techniques such as the EEG. The possible use cases span from neural-rehabilitation to early diagnosis of some neural diseases. In this work a wireline FPGA–based fNIRS system, that use SiPM sensors and dual-wavelength LED sources, has been designed and validated to work with a commercial EEG machine without reciprocal interference.

NF-ĸB as node for signal amplification during weaning.

2011

Post-lactational involution has been reported to share common features with breast tumor development. A deep characterization of the signaling triggered after weaning would help to unveil the complex relationship between involution and breast cancer. NF-κB, a crucial factor in the involuting gland, might be an important regulatory node for signal amplification after weaning; however there is limited information about the identity of NF-κB-target genes and the molecular mechanisms leading to the selection of genes involved in a particular biological process. We identified 4532 target genes in mammary gland at 48h weaning, by genome-wide analysis of regions bound by RelA(p65)-NF-κB in vivo. I…

Controlled Ovarian Stimulation Induces a Functional Genomic Delay of the Endometrium with Potential Clinical Implications

2008

Context: Controlled ovarian stimulation induces morphological, biochemical, and functional genomic modifications of the human endometrium during the window of implantation. Objective: Our objective was to compare the gene expression profile of the human endometrium in natural vs. controlled ovarian stimulation cycles throughout the early-mid secretory transition using microarray technology. Method: Microarray data from 49 endometrial biopsies obtained from LH+1 to LH+9 (n = 25) in natural cycles and from human chorionic gonadotropin (hCG) +1 to hCG+9 in controlled ovarian stimulation cycles (n = 24) were analyzed using different methods, such as clustering, profiling of biological processes…

Solution processed micro- and nano-arrays for multiplexed biosensing

2012

Comprehensive analysis of interacting proteins and genome-wide location studies of the Sas3-dependent NuA3 histone acetyltransferase complex

2014

Highlights • We characterise Sas3p and Gcn5p active HAT complexes in WT and deleted TAP-strains. • We confirm that Pdp3p interacts with NuA3, histones and chromatin regulators. • Pdp3p MS-analysis reveals its phosphorylation, ubiquitination and methylation. • Sas3p can substitute Gcn5p in acetylation of histone H3K14 but not of H3K9. • Genome-wide profiling of Sas3p supports its involvement in transcriptional elongation.

Maldivas y el delicado equilibrio entre India y China

2019

Maldivas es la nación más pequeña de Asia Meridional en términos de población, superficie y PBI. A pesar de ello, este pequeño archipiélago tiene una gran importancia estratégica, en virtud de su ubicación en medio de las rutas marítimas internacionales del océano Índico, y en su cercanía a las costas de la India. La propuesta de este artículo es exponer los cambios que se produjeron en Maldivas durante la presidencia de Abdulla Yameen en cuanto a la política interna, como así también a las relaciones exteriores, y observar en qué momento estas dos tendencias se cruzan para formar parte de una misma trama. A su vez, analizar finalmente las consecuencias que esto tiene para el país y para la…