Search results for "COGNITIVE IMPAIRMENT"

Preclinical phase of Alzheimer's disease: Guideline for recognition and study of patients with mild cognitive impairment

2002

Walking Stroop carpet: an innovative dual-task concept for detecting cognitive impairment

2013

A Perrochon,1,2,5 G Kemoun,1,2 E Watelain,3,4 A Berthoz51ISIS, Research Institute on Handicap and Aging, Paris; 2Université de Poitiers, Laboratoire Mobilité, Vieillissement et Exercice (MOVE), EA 6314, 3Université de Valenciennes, LAMIH, UMR CNRS 8201, 4Université Sud Toulon Var, HandiBio, EA 4322, La Garde, 5LPPA, UMR CNRS 7152, Collège de France, Paris, FranceBackground: Several studies have reported the potential value of the dual-task concept during locomotion in clinical evaluation because cognitive decline is strongly associated with gait abnormalities. However, current dual-task tests appear to be insufficient for early diagnosi…

M.P.S. e M.C.I. segni e sintomi

2009

Laboratory-Based Gait Variability and Habitual Gait Entropy Do Not Differentiate Community-Dwelling Older Adults from Those with Subjective Memory Co…

2020

Background Age-related cognitive decline may be delayed with appropriate interventions if those at high risk can be identified prior to clinical symptoms arising. Gait variability assessment has emerged as a promising candidate prognostic indicator, however, it remains unclear how sensitive gait variability is to early changes in cognitive abilities. Research question Do community-dwelling adults over 65 years of age with subjective memory complaints differ from those with no subjective memory concerns in terms of laboratory-measured or free-living gait variability? Methods This cross-sectional study recruited 24 (age = 73.5(SD 6.4) years) community-dwelling people with subjective memory co…

Frequency and Correlates of Mild Cognitive Impairment in Myasthenia Gravis

2023

Background: Antibodies against acetylcholine receptors (AChRs) can also target nicotinic AChRs that are present throughout the central nervous system, thus leading to cognitive dysfunctions in patients with myasthenia gravis (MG). However, the presence of cognitive impairment in MG is controversial, and the factors that may influence this risk are almost completely unknown. In this study, the frequency of mild cognitive impairment (MCI) in MG, as well as the clinical, immunological, and behavioral correlates of MCI in MG were evaluated. Methods: A total of 52 patients with MG underwent a comprehensive assessment including motor and functional scales, serological testing, and neuropsychologi…

Clinical and Sociodemographic Variables and the Level of Social Support in People with Multiple Sclerosis

2019

Wstęp. Stwardnienie rozsiane (SM) jest przewlekłą, postępującą neurologiczną chorobą, która może prowadzić do znacznej niepełnosprawności. Istotnym zasobem w radzeniu sobie z SM i innymi chorobami przewlekłymi jest wsparcie społeczne.Cel. Celem badań było określenie związku pomiędzy zmiennymi klinicznymi i socjodemograficznymi a wsparciem społecznym u osób z SM.Materiał i metody. W badaniu wykorzystano Rozszerzoną Skalę Niewydolności Ruchowej (EDSS), Skalę Niepełnosprawności Neurologicznej Szpitala Guy (GNDS) oraz Berlińskie Skale Wsparcia Społecznego Grupę badaną stanowiło 137 osób ze zdiagnozowanym SM.Wyniki. Spostrzegane wsparcie społeczne nie jest powiązane ze zmiennymi klinicznymi, tak…

The Effect of Smartphone-Based Cognitive Training on the Functional/Cognitive Markers of Schizophrenia: A One-Year Randomized Study

2020

Background: Cognitive impairment is associated with long-term disability that results in the deterioration of both the social and professional status of individuals with schizophrenia. The impact of antipsychotic therapy on cognitive function is insufficient. Cognitive training is therefore proposed as a tool for cognitive rehabilitation in schizophrenia. In this study we investigated the effect of self-administered cognitive training using a smartphone-based application on the cognitive function of paranoid schizophrenia patients focusing on response time, correct answer rate, incorrect answer rate, and fatigability to check, if these functions can be functional markers of successful cogni…

The Clock'N Test as a Possible Measure of Emotions: Normative Data Collected on a Non-clinical Population.

2016

International audience; Objective: At present emotional experience and implicit emotion regulation (IER) abilities are mainly assessed though self -reports, which are subjected to several biases. The aim of the present studies was to validate the Clock'N test, a recently developed time estimation task employing emotional priming to assess implicitly emotional reactivity and IER. Methods: In Study 1, the Clock' N test was administered to 150 healthy participants with different age, laterality and gender, in order to ascertain whether these factors affected the test results. In phase 1 participant were asked to judge the duration of seven sounds. In phase 2, before judging the duration of the…

Quantitative EEG differentiates multiple sclerosis with and without cognitive impairment from healthy controls at the beginning of the disease: preli…

2018

Background and aims: The present study aims to assess possible qEEG differences between newly diagnosed multiple sclerosis (MS) patients with or without cognitive impairment (CI). Methods: We enrolled 22 patients (18-55-years-old) treated with first-line drugs for <6 months, and 11 healthy controls. All subjects underwent neuropsychological assessment including BICAMS and BDI. EEG recordings were performed during a cognitive task (computerised “SDMT” subtest of BICAMS) and at rest. Based on neuropsychological assessment, patients were considered as affected (MSCI group) or not (MS group) by cognitive impairment. We analysed data comparing MSCI patients matched by sex, age (±5years) and e…

Il ruolo della corteccia prefrontale dorsolaterale nella memoria di riconoscimento: uso dellla Stimolazione Magnetica Transcranica per il trattamento…

Il ruolo della corteccia prefrontale dorsolaterale (DLPFC) in compiti di memoria è stato largamente documentato. Una questione ancora molto dibattuta è il grado di lateralizzazione anatomica-funzionale dei processi di controllo esecutivo della DLPFC coinvolti nella memoria di riconoscimento. Il lavoro di tesi indaga le connessioni tra DLPFC e ippocampo mediante l’applicazione di tecniche di neuromodulazione dell’eccitabilità della DLPFC che consentano di accrescere l’attività ippocampale durante compiti di memoria di riconoscimento. I primi tre studi valutano gli effetti inibitori ed eccitatori della rTMS applicata alla DLPFC sulla performance in compiti di memoria di riconoscimento, in div…