Search results for "CONST"
showing 10 items of 7706 documents
Point d'action sociale ut singuli possible contre les dirigeants d'association
2022
Minimal clinically important difference for asthma endpoints: an expert consensus report
2020
Minimal clinically important difference (MCID) can be defined as the smallest change or difference in an outcome measure that is perceived as beneficial and would lead to a change in the patient's medical management.The aim of the current expert consensus report is to provide a “state-of-the-art” review of the currently available literature evidence about MCID for end-points to monitor asthma control, in order to facilitate optimal disease management and identify unmet needs in the field to guide future research.A series of MCID cut-offs are currently available in literature and validated among populations of asthmatic patients, with most of the evidence focusing on outcomes as patient repo…
Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothal…
2015
Endocannabinoids participate in the control of neurogenesis, neural cell death and gliosis. The pharmacological effect of the fatty acid amide hydrolase (FAAH) inhibitor URB597, which limits the endocannabinoid degradation, was investigated in the present study. Cell proliferation (phospho-H3(+) or BrdU(+) cells) of the main adult neurogenic zones as well as apoptosis (cleaved caspase-3(+)), astroglia (GFAP(+)), and microglia (Iba1(+) cells) were analyzed in the hippocampus, hypothalamus and striatum of rats intraperitoneally treated with URB597 (0.3 mg/kg/day) at one dose/4-days resting or 5 doses (1 dose/day). Repeated URB597 treatment increased the plasma levels of the N-acylethanolamine…
Reconstruction of inclined air showers detected with the Pierre Auger Observatory
2014
We describe the method devised to reconstruct inclined cosmic-ray air showers with zenith angles greater than $60^\circ$ detected with the surface array of the Pierre Auger Observatory. The measured signals at the ground level are fitted to muon density distributions predicted with atmospheric cascade models to obtain the relative shower size as an overall normalization parameter. The method is evaluated using simulated showers to test its performance. The energy of the cosmic rays is calibrated using a sub-sample of events reconstructed with both the fluorescence and surface array techniques. The reconstruction method described here provides the basis of complementary analyses including an…
Testing standard and nonstandard neutrino physics with cosmological data
2012
Cosmological constraints on the sum of neutrino masses and on the effective number of neutrino species in standard and nonstandard scenarios are computed using the most recent available cosmological data. Our cosmological data sets include the measurement of the baryonic acoustic oscillation (BAO) feature in the data release 9 CMASS sample of the baryon oscillation spectroscopic survey. We study in detail the different degeneracies among the parameters, as well as the impact of the different data sets used in the analyses. When considering bounds on the sum of the three active neutrino masses, the information in the BAO signal from galaxy clustering measurements is approximately equally pow…
New horizons for fundamental physics with LISA
2022
K. G. Arun et al.
Constraint preserving boundary conditions for the Z4c formulation of general relativity
2010
We discuss high order absorbing constraint preserving boundary conditions for the Z4c formulation of general relativity coupled to the moving puncture family of gauges. We are primarily concerned with the constraint preservation and absorption properties of these conditions. In the frozen coefficient approximation, with an appropriate first order pseudo-differential reduction, we show that the constraint subsystem is boundary stable on a four dimensional compact manifold. We analyze the remainder of the initial boundary value problem for a spherical reduction of the Z4c formulation with a particular choice of the puncture gauge. Numerical evidence for the efficacy of the conditions is prese…
(Standard model) universe dominated by the right matter
2009
14 pages, 3 figures. References on late time enthropy release included, several points clarified. PACS numbers: 14.60.Pq, 98.80.Cq. ArXiv pre-print available at http://arxiv.org/abs/0806.4389
Cosmological lepton asymmetry with a nonzero mixing angle \theta13
2012
While the baryon asymmetry of the Universe is nowadays well measured by cosmological observations, the bounds on the lepton asymmetry in the form of neutrinos are still significantly weaker. We place limits on the relic neutrino asymmetries using some of the latest cosmological data, taking into account the effect of flavor oscillations. We present our results for two different values of the neutrino mixing angle \theta_{13}, and show that for large \theta_{13} the limits on the total neutrino asymmetry become more stringent, diluting even large initial flavor asymmetries. In particular, we find that the present bounds are still dominated by the limits coming from Big Bang Nucleosynthesis, …
Discontinuous Gradient Constraints and the Infinity Laplacian
2012
Motivated by tug-of-war games and asymptotic analysis of certain variational problems, we consider a gradient constraint problem involving the infinity Laplace operator. We prove that this problem always has a solution that is unique if a certain regularity condition on the constraint is satisfied. If this regularity condition fails, then solutions obtained from game theory and $L^p$-approximation need not coincide.