Search results for "CORT"

Fibromialgia: relación entre el estrés crónico, depresión, procesos inflamatorios y dolor.

2015

Por el término Fibromialgia (FM), asumimos un trastorno de etiología no conocida hasta el momento, aparentemente crónico, que se caracteriza por dolor muscular y articular generalizado incluyendo hipersensibilidad a numerosos estímulos como la presión, el frio o el calor. En la actualidad, la propia definición del cuadro, sus criterios diagnósticos y su etiopatogenia siguen siendo causa de debate. En los últimos años han ido apareciendo en la literatura numerosas hipótesis sobre el proceso de desarrollo de la FM que, aunque siguen aparentemente un patrón opuesto no se puede descartar que sean complementarias y se retroalimenten. En nuestro estudio nos hemos centrado en las hipótesis basadas…

Focal Cortical Lesions Induce Bidirectional Changes in the Excitability of Fast Spiking and Non Fast Spiking Cortical Interneurons

2014

A physiological brain function requires neuronal networks to operate within a well-defined range of activity. Indeed, alterations in neuronal excitability have been associated with several pathological conditions, ranging from epilepsy to neuropsychiatric disorders. Changes in inhibitory transmission are known to play a key role in the development of hyperexcitability. However it is largely unknown whether specific interneuronal subpopulations contribute differentially to such pathological condition. In the present study we investigated functional alterations of inhibitory interneurons embedded in a hyperexcitable cortical circuit at the border of chronically induced focal lesions in mouse …

Conferència "La figura humana de Sanchis Guarner en al seu temps"

2011

Conferència "La dedicació de Sanchis Guarner a la filologia". Homenatge al filòleg Manuel Sanchis Guarner.

Action in Perception: Prominent Visuo-Motor Functional Symmetry in Musicians during Music Listening.

2015

Musical training leads to sensory and motor neuroplastic changes in the human brain. Motivated by findings on enlarged corpus callosum in musicians and asymmetric somatomotor representation in string players, we investigated the relationship between musical training, callosal anatomy, and interhemispheric functional symmetry during music listening. Functional symmetry was increased in musicians compared to nonmusicians, and in keyboardists compared to string players. This increased functional symmetry was prominent in visual and motor brain networks. Callosal size did not significantly differ between groups except for the posterior callosum in musicians compared to nonmusicians. We conclude…

An extensive pattern of atypical neural speech-sound discrimination in newborns at risk of dyslexia.

2019

Objective: Identifying early signs of developmental dyslexia, associated with deficient speech-sound processing, is paramount to establish early interventions. We aimed to find early speech-sound processing deficiencies in dyslexia, expecting diminished and atypically lateralized event-related potentials (ERP) and mismatch responses (MMR) in newborns at dyslexia risk. Methods: ERPs were recorded to a pseudoword and its variants (vowel-duration, vowel-identity, and syllable-frequency changes) from 88 newborns at high or no familial risk. The response significance was tested, and group, laterality, and frontality effects were assessed with repeated-measures ANOVA. Results: An early positive a…

Structural changes induced by daily music listening in the recovering brain after middle cerebral artery stroke: a voxel-based morphometry study

2014

[Abstract.] Music is a highly complex and versatile stimulus for the brain that engages many temporal, frontal, parietal, cerebellar, and subcortical areas involved in auditory, cognitive, emotional, and motor processing. Regular musical activities have been shown to effectively enhance the structure and function of many brain areas, making music a potential tool also in neuro- logical rehabilitation. In our previous randomized controlled study, we found that listening to music on a daily basis can improve cognitive recovery and improve mood after an acute mid- dle cerebral artery stroke. Extending this study, a voxel-based morphometry (VBM) analysis utilizing cost function masking was perf…

Las cortes valencianas de la época foral. propuesta de edición.

1993

1982. Las elecciones del cambio. 28 de octubre de 1982. El triunfo del PSOE: 10.134.310 de votos (48,4%) y 202 diputados La hegemonía socialista

2014

"Las elecciones del cambio. 28 de octubre de 1982. El triunfo del PSOE: 10.134.310 de votos (48,4%) y 202 diputados. La hegemonía socialista" forma parte de la investigación que realice sobre el periodo histórico en que los socialistas valencianos fueron la fuerza política hegemónica en la Comunidad Valenciana. El presente capítulo forma parte de estudio realizado en los años 2005-2013 que formaban parte de los materiales complementarios de varias asignaturas de los estudios de Ciencias Políticas y de la Administración de la Universidad de Valencia y que lo titulo: "La hegemonía socialista en la Comunidad Valenciana. El PSPV-PSOE. 1982-1995". 1982 será el año del cambio político en España. …

El Valle de Ayora

1982

¿Qué es el Valle de Ayora? El Valle de Ayora forma una comarca situada en una espaciosa hoya rodeada de elevados montes. Consta de seis municipios: Cofrentes, Jalance, Jarafuel, Teresa de Cofrentes, Zarra y Ayora. Las villas están situadas en lugares estratégicos, coincidiendo en ellas alturas coronadas de castillos —a excepción de Zarra—, de larga tradición histórica. Todos estos castillos datan de siglos, algunos incluso de antiguos bastiones romanos. Durante la época musulmana el Valle tuvo mucha importancia por ser zona de tránsito entre reinos y frontera de los mismos. El Valle es una comarca natural con características muy comunes. Todas las villas de la comarca se encuentran en el ce…

Study of the population of immature neurons in the adult piriform cortex layer II

2019

Physiological studies indicate that the piriform or primary olfactory cortex of adult mammals exhibits a high degree of synaptic plasticity. Interestingly, a subpopulation of cells in the layer II of the adult piriform cortex expresses neurodevelopmental markers, such as the polysialylated form of neural cell adhesion molecule (PSA-NCAM) or doublecortin (DCX). This study analyzes the nature, origin, and potential function of these poorly understood cells in mice. As previously described in rats, most of the PSANCAM expressing cells in layer II could be morphologically classified as tangled cells and only a small proportion of larger cells could be considered semilunar-pyramidal transitional…