Search results for "CSP"
showing 10 items of 26 documents
Preparing a revision of the International Code of Nomenclature of Prokaryotes
2020
The Editorial Board of the International Code of Nomenclature of Prokaryotes here explains the proposed procedure towards the production of the next revision of the Prokaryotic Code, to include public discussion of a draft version, to be prepared by the editors, followed by balloting of the members of the International Committee on Systematics of Prokaryotes.
The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor
2021
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-stress-regulated protein exhibiting cytoprotective properties through a poorly understood mechanism in various in vitro and in vivo models of neuronal and non-neuronal damage. Although initially characterized as a secreted neurotrophic factor for midbrain dopamine neurons, MANF has recently gained more interest for its intracellular role in regulating the ER homeostasis, including serving as a cofactor of the chaperone glucose-regulated protein 78 (GRP78). We aimed for a better understanding of the neuroprotective mechanisms of MANF. Here we show for the first time that MANF promotes the survival of …
The effect of CEOs’ turnover on the CSP of French firms
2016
International audience
La juridicisation de l’activité syndicale durant le Front populaire (CGT, CFTC, CSPF)
2014
National audience; Dans l’histoire du mouvement ouvrier, le Front populaire constitue un tournant puisque les syndicats tendent à s’affirmer en tant que véritables acteurs sociaux grâce à une représentativité nouvellement acquise dans le cadre d’une expérience unique d’un syndicalisme de masse. La signature des accords Matignon et les différentes dispositions juridiques qui suivent - loi sur la conciliation et l’arbitrage du 31 décembre 1936 et création de la Cour supérieure d’arbitrage en 1938 - ouvrent un chantier considérable en termes de droit du travail qui nécessite un investissement important des militants syndicaux désormais impliqués dans des procédures nouvelles (délégués-ouvriers…
MED parallel system powered by concentrating solar power (CSP): model and case study: Trapani, Sicily
2014
Abstract: This work presents an overlook on a new model that simulates the physical operation in steady state of a multi-effect distillation (MED) plant with parallel-feed (P) configuration. This model includes the consumption of steam with steam ejectors, and its validation was done using data from a real MED industrial plant using a thermal vapor compressor (TVC) operating in Italy, in the Sicilian city of Trapani. Results show that the MED model returns accurate predictions of the plant behavior, very useful for a first analysis on such type of investments. This MED model was also integrated into the system advisor model developed by the US National Renewable Energy Laboratory. Simulatio…
TRACE Code Analyses for the IAEA ICSP on “Integral PWR Design Natural Circulation Flow Stability and Thermo-Hydraulic Coupling of Containment and Pri…
2011
Considering the world energy demand increase in order to fulfill an environmental and economic sustainability, the energy policy of each country has to diversify the sources of energy and use stable, safe energy production option able of producing electricity in a clean way contributing in cutting the CO2 emission. In the framework of the sustainable development, today the use of advanced nuclear power plant, have an important role in the environmental and economic sustainability of country energy strategy. In the last 20 years, in fact, the international community, taking into account the operational experience of the nuclear reactors, starts the development of new advanced reactor designs…
Novel NG2-CreERT2 knock-in mice demonstrate heterogeneous differentiation potential of NG2 glia during development
2014
NG2 (nerve/glia antigen-2) is a type I transmembrane glycoprotein and also known as chondroitin sulfate proteoglycan 4. In the parenchyma of the central nervous system, NG2-expressing (NG2(+) ) cells have been identified as a novel type of glia with a strong potential to generate oligodendrocytes (OLs) in the developing white matter. However, the differentiation potential of NG2 glia remained controversial, largely attributable to shortcomings of transgenic mouse models used for fate mapping. To minimize these restrictions and to more faithfully mimic the endogenous NG2 expression in vivo, we generated a mouse line in which the open reading frame of the tamoxifen-inducible form of the Cre D…
Prostate health index (PHI) as a reliable biomarker for prostate cancer: a systematic review and meta-analysis.
2022
Abstract Objectives Prostate cancer (PCa) represents the second most common solid cancer in men worldwide. In the last decades, the prostate health index (PHI) emerged as a reliable biomarker for detecting PCa and differentiating between non-aggressive and aggressive forms. However, before introducing it in clinical practice, more evidence is required. Thus, we performed a systematic review and meta-analysis for assessing the diagnostic performance of PHI for PCa and for detecting clinically significant PCa (csPCa). Methods Relevant publications were identified by a systematic literature search on PubMed and Web of Science from inception to January 11, 2022. Results Sixty studies, including…
Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic
2021
Association of Surgeons in Training Surgical Summit, online, 17 Oct 2020 - 17 Oct 2020 2021 Virtual Annual Meeting / Surgical Research Society, online, 24 Mar 2021 - 25 Mar 2021, National Research Collaborative Meeting, online, 10 Dec 2020 - 10 Dec 2020, Royal Australasian College of Surgeons Annual Academic Surgery Conference, online, 5 Nov 2020 - 5 Nov 2020; The British journal of surgery : BJS 108(12), 1448-1464 (2021). doi:10.1093/bjs/znab336
Eliminating Factor H-Binding Activity of Borrelia burgdorferi CspZ Combined with Virus-Like Particle Conjugation Enhances Its Efficacy as a Lyme Dise…
2018
The spirochete Borrelia burgdorferi is the causative agent of Lyme disease, the most common tick-borne disease in the U.S and Europe. No potent human vaccine is currently available. The innate immune complement system is vital to host defense against pathogens, as complement activation on the surface of spirochetes results in bacterial killing. Complement system is inhibited by the complement regulator factor H. To escape killing, B. burgdorferi produces an outer surface protein CspZ that binds factor H to inhibit complement activation on the cell surface. Immunization with CspZ alone does not protect mice from infection, which we speculate is because factor H-binding cloaks potentially pro…