Search results for "Cave"

showing 10 items of 606 documents

Interaction of Human Phagocytes with Pigmentless Aspergillus Conidia

2000

ABSTRACT A defect in the pksP gene of Aspergillus fumigatus is associated with the loss of conidial pigmentation, a profound change of the conidial surface structure, and reduced virulence. The structural change of the conidial surface structure was not observed in similar A. nidulans wA mutants. Our data indicate that the pigment of both species is important for scavenging reactive oxygen species and for protection of conidia against oxidative damage.

ImmunologyVirulencemedicine.disease_causeMicrobiologyAspergillus nidulansConidiumAspergillus fumigatusMicrobiologyMultienzyme ComplexesAspergillus nidulansmedicineskin and connective tissue diseaseschemistry.chemical_classificationPhagocytesAspergillusReactive oxygen speciesbiologyAspergillus fumigatusfungiFungal geneticsFree Radical ScavengersPigments BiologicalSpores FungalOxidantsbiology.organism_classificationInfectious DiseaseschemistryParasitologysense organsFungal and Parasitic InfectionsOxidative stressInfection and Immunity
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Kinetics of the lipoperoxyl radical-scavenging activity of indicaxanthin in solution and unilamellar liposomes

2007

Abstract The reaction of the phytochemical indicaxanthin with lipoperoxyl radicals generated in methyl linoleate methanol solution by 2,20-azobis(2,4-dimethylvaleronitrile), and in aqueous soybean phosphatidylcholine unilamellar liposomes by 2,20-azobis(2- amidinopropane)hydrochloride, was studied. The molecule acts as a chain-terminating lipoperoxyl radical scavenger in solution, with a calculated inhibition constant of 3.63 £ 105M21 s21, and a stoichiometric factor approaching 2. Indicaxanthin incorporated in liposomes prevented lipid oxidation, inducing clear-cut lag periods and decrease of the propagation rate. Both effects were concentration-dependent, but not linearly related to the p…

Indicaxanthin membranes radical scavenger liposomesLipid PeroxidesAntioxidant12-DipalmitoylphosphatidylcholinePyridinesmedicine.medical_treatmentRadicalLipid Bilayersalpha-TocopherolAmidinesContext (language use)In Vitro TechniquesBiochemistryAntioxidantsLipid peroxidationchemistry.chemical_compoundLipid oxidationSuspensionsPhosphatidylcholineNitrilesmedicineOrganic chemistryLiposomeDose-Response Relationship DrugMolecular StructureMethanolDrug SynergismGeneral MedicineFree Radical ScavengersBetaxanthinsSolutionsKineticschemistryLinoleic AcidsLiposomesPhosphatidylcholinesSolventsLipid PeroxidationIndicaxanthinAzo CompoundsOxidation-ReductionNuclear chemistry
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Dinotrema cavernicola sp. n. (Hymenoptera, Braconidae, Alysiinae), a new species of the genus Dinotrema Foerster from caves of Spain

2014

Dinotrema cavernicola sp. n. was collected in two caves in Spain. This is the first Dinotrema species known to occur in caves. This new species is described and compared to D. affine (Fischer, 1973) and D. collybiae Munk & Peris-Felipo, 2014, species sharing a mid-longitudinal carina on the propodeum.

InsectaKulbastaviaDinotremaHymenopteraCarbotripluridaBraconidaetaxonomyGenusPropodeumlcsh:ZoologyBilaterialcsh:QL1-991AlysiinaePterygotageography.geographical_feature_categorybiologyCephalornisCircumscriptional namesCavernicolaBoltonocostidaeIchneumonoideaTiphiinaeCircumscriptional nameBraconidaeCoelenterataArthropodaHymenopteridaNephrozoaProtostomiaBasalZoologyDinotrema cavernicolaAnimaliaCircumscriptional names of the taxon undercavesCaveEumetabolaBraconidaeCephalornisEcology Evolution Behavior and SystematicsAlysiinaeCystomastacoides kiddoAlysiinaeAnimalianew speciesgeographyHymenopteraAnimaliaDipteraStrashila incredibilisbiology.organism_classificationHymenopteraNotchiaInsect ScienceAlysiiniEcdysozoaJournal of Hymenoptera Research
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Internalization of Echovirus 1 in Caveolae

2002

ABSTRACT Echovirus 1 (EV1) is a human pathogen which belongs to the Picornaviridae family of RNA viruses. We have analyzed the early events of infection after EV1 binding to its receptor α2β1 integrin and elucidated the route by which EV1 gains access to the host cell. EV1 binding onto the cell surface and subsequent entry resulted in conformational changes of the viral capsid as demonstrated by sucrose gradient sedimentation analysis. After 15 min to 2 h postinfection (p.i.) EV1 capsid proteins were seen in vesicular structures that were negative for markers of the clathrin-dependent endocytic pathway. In contrast, immunofluorescence confocal microscopy showed that EV1, α2β1 integrin, and …

IntegrinsReceptors CollagenEchovirusmedia_common.quotation_subjectCaveolin 1ImmunologyIntegrinCaveolaemedicine.disease_causeCaveolinsMicrobiologyClathrin03 medical and health sciencesCapsidVirologyCaveolaeCaveolinEnterovirus InfectionsTumor Cells CulturedmedicineAnimalsHumansInternalization030304 developmental biologymedia_common0303 health sciencesMicroscopy Confocalbiology030302 biochemistry & molecular biologyMolecular biologyClathrinEnterovirus B HumanVirus-Cell InteractionsCell biologyMicroscopy ElectronViral replicationInsect ScienceCaveolin 1biology.proteinRabbitsbeta 2-MicroglobulinJournal of Virology
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Télécollaboration asymétrique en réalité virtuelle

2016

National audience; Nous présentons une première étude de combinaison de deux systèmes asymétriques de réalité virtuelle dans un contexte de travail collaboratif : un système de type CAVE et un casque immersif. L’architecture, de type serveur-client, permet une collaboration entre plusieurs utilisateurs. Les expériences sur une tâche de construction de puzzles en un temps limité, seul et en collaboration, montrent que l’utilisation combinée de systèmes asymétriques CAVE et casques permet d’améliorer les performances des utilisateurs. Par ailleurs les utilisateurs préfèrent le travail en collaboration et sont plus efficaces ensemble. Ces résultats ouvrent des perspectives intéressantes de com…

InteractionRéalité virtuelleSynthèse d'image et réalité virtuelle [Informatique]Casque immersif[INFO.INFO-GR] Computer Science [cs]/Graphics [cs.GR]CAVE[ INFO.INFO-GR ] Computer Science [cs]/Graphics [cs.GR]Collaboration[INFO.INFO-GR]Computer Science [cs]/Graphics [cs.GR]
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Sulfuric Acid Caves of Italy: An Overview

2016

ItalyH2SSettore GEO/04 - Geografia Fisica E GeomorfologiaSAS caveGypsum
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Dissolution‐corrosion measurements with limestone and gypsum tablets in active sulphuric acid caves of southern Italy

2022

Dissolution‐corrosion (DC) represents an important factor for speleogenesis, and can be measured monitoring weight variation over time of carbonate and gypsum tablets exposed in underground environments. The oxidation of H2S produces H2SO4, which in carbonate host rock induces the surface of carbonate tablets to be rapidly corroded by sulphuric acid, whereby CaCO3 is replaced by CaSO4∙2H2O, producing a significant weight gain. We describe preliminary results of DC monitoring in four still‐active SAS systems, including Ninfe Cave and Terme Sibarite (Calabria), Fetida Cave (Apulia), and Acqua Fitusa Spring Cave (Sicily). The tablets have been set inside the caves, in three different condition…

ItalySettore GEO/04 - Geografia Fisica E GeomorfologiaDissolution‐corrosionsulphuric acid cavelimestone tabletSettore GEO/08 - Geochimica E Vulcanologia
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Potential Antipsoriatic Avarol Derivatives as Antioxidants and Inhibitors of PGE2 Generation and Proliferation in the HaCaT Cell Line

2004

The synthesis and structure-activity relationships for a series of 14 new avarol derivatives as antioxidants and inhibitors of cell proliferation and PGE(2) generation in human keratinocytes are described. Compound 6 (thiosalicylic derivative) was the most potent inhibitor of superoxide generation in human neutrophils and also potently inhibited PGE(2) generation in the human keratinocyte HaCaT cell line. Compound 7(3'-methylaminoavarone) presented the best antiproliferative profile, by the inhibition of (3)H-thymidine incorporation in HaCaT cells, with potency similar to the reference compound anthralin. None of the avarol derivatives showed any sign of cytotoxicity measured as LDH release…

KeratinocytesPharmaceutical ScienceAntioxidantsDinoprostoneAnalytical ChemistryInhibitory Concentration 50Structure-Activity Relationshipchemistry.chemical_compoundDrug DiscoverymedicineHumansStructure–activity relationshipCytotoxicityPharmacologyL-Lactate DehydrogenaseSuperoxideCell growthOrganic ChemistryFree Radical ScavengersSalicylatesIn vitroHaCaTmedicine.anatomical_structureItalyComplementary and alternative medicinechemistryBiochemistryCell cultureMolecular MedicineKeratinocyteSesquiterpenesJournal of Natural Products
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Holocene interaction of maritime and continental climate in Central Europe: New speleothem evidence from Central Germany

2019

Central European climate is strongly influenced by North Atlantic (Westerlies) and Siberian High circulation patterns, which govern precipitation and temperature dynamics and induce heterogeneous climatic conditions, with distinct boundaries between climate zones. These climate boundaries are not stationary and shift geographically, depending on long-term atmospheric conditions. So far, little is known about past shifts of these climate boundaries and the local to regional environmental response prior to the instrumental era.\ud \ud High resolution multi-proxy data (stable oxygen and carbon isotope ratios, S/Ca and Sr/Ca) from two Holocene stalagmites from Bleßberg Cave (Thuringia) are used…

L700Global and Planetary Changegeographygeography.geographical_feature_category010504 meteorology & atmospheric sciencesOceanic climateSpeleothemF800020206 networking & telecommunicationsStalagmiteWesterlies02 engineering and technology15. Life on landOceanography01 natural sciencesSiberian HighCave13. Climate actionNorth Atlantic oscillation0202 electrical engineering electronic engineering information engineeringPhysical geographyHoloceneGeology0105 earth and related environmental sciencesGlobal and Planetary Change
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Reply to the “Comment by Delmelle et al. (2013) on ‘Scavenging of sulfur, halogens and trace metals by volcanic ash: The 2010 Eyjafjallajökull erupti…

2014

Abstract With this short communication we address the principal issues raised by Delmelle et al. (2014) in relation to the work of Bagnato et al. (2013) concerning the 2010 eruption of Eyjafjallajokull, Iceland. The principal conclusions of the work of Bagnato et al. (2013) include the observation that protracted gas-aerosol interaction in the plume promotes selective leaching of cation species from ash, with alkalis and Ca (and, among trace elements, Zn and Cu) being more rapidly re-mobilized (and transferred to soluble surface salts) relative to more inert elements (Mg, Ti). They also observed that adsorption onto ash surfaces is a major atmospheric sink of volcanic acidic gases, with 282…

LEACHING OF ASHgeographygeography.geographical_feature_categoryChemistryMineralogychemistry.chemical_elementexplosive volcanismSulfurSettore GEO/08 - Geochimica E VulcanologiaPlumeexplosive volcanism; VOLCANIC ASH; EyjafjallajökullAdsorptionEyjafjallajökullVolcanoVOLCANIC ACID GASGeochemistry and PetrologyINTERACTION ASH-PLUMEHalogenddc:5502010 EYJAFJALLAJOKULL ERUPTIONSelective leachingVOLCANIC ASHScavengingVolcanic ashGeochimica et Cosmochimica Acta
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