Search results for "Center"
showing 10 items of 1724 documents
GABA, receptor mediated fast synaptic inhibition in the rabbit brain-stem respiratory system
1991
The involvement of GABA mediated neurotransmission in the central control of respiration was investigated by administration of the specific GABAA receptor agonist muscimol and the specific GABAA receptor antagonist biculline into the fourth cerebral ventricle of the rabbit. Cycle-triggered averaging of the phrenic nerve activity (PNA) was used to quantify drug-induced changes of the central respiratory pattern. Muscimol reduced the peak amplitude of PNA and increased the duration of the respiratory phases. High amounts of muscimol led to a long-lasting but reversible central apnea. Bicuculline very effectively blocked the effects of externally applied muscimol. Blockade of intrinsically act…
Agora Center on yliopiston monitieteinen projektitoimisto
2014
Agora Centerin missio on ihmistä palvelevan teknologian sovellusten ja yhteiskuntaa hyödyttävien innovaatioiden kehittäminen ja tutkimus. Kansainvälisiä läpimurtoja tai vaikuttavia tutkimustuloksia on saatu mm. oppimisvaikeuksiin, teollisiin prosesseihin, sosiaali- ja terveyssektorin kehittämiseen sekä turvallisuuteen liittyvillä alueilla. Tutkimuksen kohteena ovat maailmanlaajuiset ihmiskuntaa koskettavat toimintamallit ja innovaatiot. nonPeerReviewed
Estimating economic severity of Air Traffic Flow Management regulations
2021
The development of trajectory-based operations and the rolling network operations plan in European air traffic management network implies a move towards more collaborative, strategic flight planning. This opens up the possibility for inclusion of additional information in the collaborative decision-making process. With that in mind, we define the indicator for the economic risk of network elements (e.g., sectors or airports) as the expected costs that the elements impose on airspace users due to Air Traffic Flow Management (ATFM) regulations. The definition of the indicator is based on the analysis of historical ATFM regulations data, that provides an indication of the risk of accruing dela…
Perdre le fil: labyrinthes de la littérature française moderne
2009
From the day when Theseus killed the Minotaur, the Maze turned into a form in search of meaning, and became useless. As a result, one was enjoined to ascribe nw meanings to the empty strcuture. Modern writers, when confronted with such a void, will have explored all its possibilities: while some of them, like Michel Butor, dismiss the sacred dimensions, others, like Serge Doubrovsky, see in it the image of the self (the body, the psyche...), and others still, like Raymond Roussel, Alain Robbe-Grillet or Georges Pererc, make of the pure geometrical structure of the labyrinth an aesthetic model, and thus a mirror of the work of art. However, one still have to ask whether the labrinth is a val…
Catalytic Enantioselective Aza-Reformatsky Reaction with Cyclic Imines
2016
A catalytic highly enantioselective aza-Reformatsky reaction with cyclic aldimines and ketimines for the synthesis of chiral b-amino esters with good yields and excellent enantioselectivities is reported.Areadily available diaryl prolinol is used as a chiral ligand, ZnMe2 as a zinc source and ethyl iodoacetate as reagent in the presence of air atmosphere. The reaction with cyclic ketimines generates a quaternary stereocenter with excellent levels of enantioselectivity. Furthermore, five-membered N-sulfonyl ketimines were used as electrophiles with good enantiomeric excesses, under the optimized reaction conditions. Moreover, several chemical transformations were performed with the chiral b-…
GENERALIZED HYPERCENTERS IN INFINITE GROUPS
2011
We consider the so-called generalized center, defined by Agrawal, in the slightly wider context of periodic groups and try to find out where additional conditions are needed for refinements. In particular we consider the final terms of the corresponding ascending sequences.
Some generalizations of the center of a ring
1978
Si generalizza la nozione di ipercentro introdotta da Herstein in [3] e si trova una forma equivalente alla congettura di Koethe.
A Multicenter Trial of Specific Local Nasal Immunotherapy
2000
Objective: To assess the efficacy and safety of specific local nasal immunotherapy (LNIT) in powder form in patients with allergic rhinitis, using subjective and objective parameters. Study Design: A double-blind randomized multicenter trial of 102 patients with allergic rhinitis who were treated with specific LNIT for 8 consecutive months. Methods: After identifying allergens with the skin prick test and sensitization threshold dose with the specific nasal provocation test, 102 patients were selected, of whom 55 were allergic to mites and 47 were allergic to Graminaceae or Parietaria pollen. The specific treatments were self-administered using an insufflator in two phases (phase 1: increas…
Stereoselective synthesis of the naturally occurring 2-pyranone dodoneine
2008
The first total synthesis of the naturally occurring dihydropyranone dodoneine is reported. Asymmetric allylation reactions were used for the stereoselective generation of the two stereogenic centers. The pyranone ring was created by ring-closing metathesis. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Enantiodifferentiation of acyclic phosphonium salts in chiral liquid crystalline solutions
2006
Abstract The enantiodifferentiation of acyclic phosphonium salts bearing a stereogenic centre, whether on the phosphorus atom or on one of its substituents, was investigated by 2 H–{ 1 H}, 13 C–{ 1 H} and 31 P–{ 1 H} NMR in chiral liquid crystals composed of a polypeptide dissolved in an organic solvent. For the first time, the enantiomers of P-chirogenic phosphorus compounds were discriminated in these anisotropic media, affording good to excellent separation of the signals, allowing the determination of their proportion. While 31 P–{ 1 H} NMR spectra showed no chiral separation, 2 H–{ 1 H} NMR was efficient in the enantiodifferentiation of an isotopically labelled compound. Better still, …