Search results for "Cero"

The mechanism of aquaporin inhibition by gold compounds elucidated by biophysical and computational methods

2017

The inhibition of water and glycerol permeation via human aquaglyceroporin-3 (AQP3) by gold(iii) complexes has been studied by stopped-flow spectroscopy and, for the first time, its mechanism has been described using molecular dynamics (MD), combined with density functional theory (DFT) and electrochemical studies. The obtained MD results showed that the most effective gold-based inhibitor, anchored to Cys40 in AQP3, is able to induce shrinkage of pores preventing glycerol and water permeation. Moreover, the good correlation between the affinity of the Au(iii) complex to Cys binding and AQP3 inhibition effects was highlighted, while no influence of the different oxidative character of the c…

La spada di Tuberone. Una citazione della pro Ligario nell’Institutio oratoria di Quintiliano

2018

Cicero's Pro Ligario is frequently mentioned in Quintilian’s Institutio Oratoria. The author is very aware of the importance of the text for the social and historical context in which it was pronounced and for the ambiguous presence of Caesar. Among these quotations stands out in the treaty the evocation of the sword of Tubero (Cic. Lig. 9) in five different contexts that confirm the Quintilian’s remarkable interest for this text.

Diacylglycerol-containing oleic acid induces increases in [Ca(2+)](i) via TRPC3/6 channels in human T-cells.

2011

Though most of the studies have focused on the effects of free fatty acids on T-cell activation, fatty acids incorporated into plasma membrane phospholipids may also affect cell signaling via diacylglycerol (DAG), generally produced by phospholipid hydrolysis. In the present study, we have synthesized a DAG-containing oleic acid and studied its implication in the modulation of calcium signaling in human Jurkat T-cells. 1-palmitoyl-2-oleoyl-sn-glycerol (POG) induced a dose-dependent increase in [Ca(2+)](i). This effect was due to the presence of oleic acid at the sn-2 position as no differences were observed between POG and 1-stearoly-2-oleoyl-sn-glycerol (SOG). However, the substitution of …

Per un’edizione critica di Boezio, Commentaria in Topica Ciceronis.

2001

Sitne scripsisses an cavisses in Ciceronis Topicis (1, 4) legendum

1991

De codicis Halensis momento ad Ciceronis Topica edenda

2001

Glycerol selective oxidation to lactic acid over AuPt nanoparticles; Enhancing reaction selectivity and understanding by support modification

2020

2 Schemes, 3 Tables, 5 Figures.

The Effect of Long-Term Storage on the Biological and Histological Properties of Cryopreserved Amniotic Membrane

2011

Cryopreserved amniotic membrane (AM) is widely used in ophthalmology because of its anti-angiogenic, anti-inflammatory, and wound healing promoting capabilities. A common method to conserve the tissue is the storage in cryo-medium containing 50% glycerol at -80°C. The aim of this study was to examine the influence of storage time on the sterility as well as the histological and biological properties of cryopreserved AM.Amniotic membrane from different donors was stored in cell culture media containing 50% glycerol for different time periods, on average 4 months (group 1), 15 months (group 2), and 24 months (group 3), at -80°C. Samples of the tissue and cryo-medium were examined for bacteria…

Lipid and fatty acid variations inCiona intestinalis ovary after tri-n-butyltin(IV)chloride exposure

2005

Reduction of total lipids (TL) content and significant variations of triglyceride (TG) and phospholipid (PL) fractions were observed as a consequence of exposure of Ciona intestinalis ovaries to tributyltin chloride (TBTCL) solutions. In particular, an evident TG decrease and a PL increase were observed, which probably provoked an increment in membrane fluidity, because of the high concentration of long chain fatty acids and, as a consequence, PL. This could be a cell adaptive standing mechanism towards the pollutants, as observed in Saccharomyces cerevisiae. Also the increase in the content of the polyunsaturated fatty acids (PUFA), important in the synthesis of compounds such as prostagla…

Análisis del comportamiento espacio-temporal intradestino mediante GPS : Una aproximación de los visitantes independientes de crucero en la ciudad de…

2020

El presente trabajo tiene como objetivo profundizar en el análisis de los patrones de comportamiento espacio-temporal de los visitantes en destino, una escala de trabajo insuficientemente desarrollada. La investigación aplica un enfoque multimétodo, que combina el uso de GPS con una encuesta, al conocimiento de los patrones espaciales de los cruceristas que visitan la ciudad de Valencia de manera independiente. Los resultados obtenidos evidencian la polarización de los flujos en el centro histórico de la ciudad, dentro de un patrón mayoritario de único nodo, una dinámica que conviene gestionar adecuadamente para prevenir la congestión y poner en valor otros atractivos urbanos. La redistribu…